Christiane A. Opitz
Christiane A. Opitz
Group Leader, Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ)
Verified email at dkfz.de - Homepage
Title
Cited by
Cited by
Year
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
CA Opitz, UM Litzenburger, F Sahm, M Ott, I Tritschler, S Trump, ...
Nature 478 (7368), 197-203, 2011
12362011
Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts
I Makarenko, CA Opitz, MC Leake, C Neagoe, M Kulke, JK Gwathmey, ...
Circulation research 95 (7), 708-716, 2004
3482004
Toll‐like receptor engagement enhances the immunosuppressive properties of human bone marrow‐derived mesenchymal stem cells by inducing indoleamine‐2, 3‐dioxygenase‐1 via …
CA Opitz, UM Litzenburger, C Lutz, TV Lanz, I Tritschler, A Köppel, ...
Stem cells 27 (4), 909-919, 2009
3272009
Isoform diversity of giant proteins in relation to passive and active contractile properties of rabbit skeletal muscles
LG Prado, I Makarenko, C Andresen, M Krüger, CA Opitz, WA Linke
The Journal of general physiology 126 (5), 461-480, 2005
2812005
Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness
C Neagoe, CA Opitz, I Makarenko, WA Linke
Journal of Muscle Research & Cell Motility 24 (2), 175-189, 2003
2092003
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
M Platten, EAA Nollen, UF Röhrig, F Fallarino, CA Opitz
Nature reviews Drug discovery 18 (5), 379-401, 2019
1812019
Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart
CA Opitz, MC Leake, I Makarenko, V Benes, WA Linke
Circulation research 94 (7), 967-975, 2004
1812004
Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR
UM Litzenburger, CA Opitz, F Sahm, KJ Rauschenbach, S Trump, ...
Oncotarget 5 (4), 1038, 2014
1632014
Damped elastic recoil of the titin spring in myofibrils of human myocardium
CA Opitz, M Kulke, MC Leake, C Neagoe, H Hinssen, RJ Hajjar, WA Linke
Proceedings of the National Academy of Sciences 100 (22), 12688-12693, 2003
1412003
The indoleamine-2, 3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells
CA Opitz, UM Litzenburger, U Opitz, F Sahm, K Ochs, C Lutz, W Wick, ...
PloS one 6 (5), e19823, 2011
1312011
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress
F Sahm, I Oezen, CA Opitz, B Radlwimmer, A Von Deimling, T Ahrendt, ...
Cancer research 73 (11), 3225-3234, 2013
1052013
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress
F Sahm, I Oezen, CA Opitz, B Radlwimmer, A Von Deimling, T Ahrendt, ...
Cancer research 73 (11), 3225-3234, 2013
1052013
Tryptophan degradation in autoimmune diseases
CA Opitz, W Wick, L Steinman, M Platten
Cellular and Molecular Life Sciences 64 (19), 2542-2563, 2007
872007
Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma
K Ochs, F Sahm, CA Opitz, TV Lanz, I Oezen, PO Couraud, ...
Journal of neuroimmunology 265 (1-2), 106-116, 2013
692013
Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2, 3-dioxygenase 1 (IDO1)
TV Lanz, CA Opitz, PP Ho, A Agrawal, C Lutz, M Weller, AL Mellor, ...
Stem cells and development 19 (5), 657-668, 2010
562010
Pirfenidone inhibits TGF-β expression in malignant glioma cells
I Burghardt, F Tritschler, CA Opitz, B Frank, M Weller, W Wick
Biochemical and biophysical research communications 354 (2), 542-547, 2007
542007
Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental autoimmune encephalomyelitis
TV Lanz, S Becker, M Osswald, S Bittner, MK Schuhmann, CA Opitz, ...
Proceedings of the National Academy of Sciences 110 (36), 14735-14740, 2013
442013
Suppression of TDO‐mediated tryptophan catabolism in glioblastoma cells by a steroid‐responsive FKBP52‐dependent pathway
M Ott, UM Litzenburger, KJ Rauschenbach, L Bunse, K Ochs, F Sahm, ...
Glia 63 (1), 78-90, 2015
432015
Microenvironmental clues for glioma immunotherapy
M Platten, K Ochs, D Lemke, C Opitz, W Wick
Current neurology and neuroscience reports 14 (4), 440, 2014
402014
Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation
T Kessler, F Sahm, A Sadik, D Stichel, A Hertenstein, G Reifenberger, ...
Neuro-oncology 20 (3), 367-379, 2018
362018
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