A molecular roadmap of reprogramming somatic cells into iPS cells JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ... Cell 151 (7), 1617-1632, 2012 | 1023 | 2012 |
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes E Mariño, JL Richards, KH McLeod, D Stanley, YA Yap, J Knight, ... Nature immunology 18 (5), 552-562, 2017 | 702 | 2017 |
Class-switch recombination occurs infrequently in germinal centers JA Roco, L Mesin, SC Binder, C Nefzger, P Gonzalez-Figueroa, ... Immunity 51 (2), 337-350. e7, 2019 | 562 | 2019 |
A predictive computational framework for direct reprogramming between human cell types OJL Rackham, J Firas, H Fang, ME Oates, ML Holmes, AS Knaupp, ... Nature genetics 48 (3), 331-335, 2016 | 317 | 2016 |
Reprogramming roadmap reveals route to human induced trophoblast stem cells X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ... Nature 586 (7827), 101-107, 2020 | 184 | 2020 |
A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs C Pflueger, D Tan, T Swain, T Nguyen, J Pflueger, C Nefzger, JM Polo, ... Genome research 28 (8), 1193-1206, 2018 | 175 | 2018 |
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming X Liu, CM Nefzger, FJ Rossello, J Chen, AS Knaupp, J Firas, E Ford, ... Nature methods 14 (11), 1055-1062, 2017 | 174 | 2017 |
Mesenchymal niche-derived neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium T Jardé, WH Chan, FJ Rossello, TK Kahlon, M Theocharous, TK Arackal, ... Cell stem cell 27 (4), 646-662. e7, 2020 | 127 | 2020 |
Transient and permanent reconfiguration of chromatin and transcription factor occupancy drive reprogramming AS Knaupp, S Buckberry, J Pflueger, SM Lim, E Ford, MR Larcombe, ... Cell stem cell 21 (6), 834-845. e6, 2017 | 126 | 2017 |
Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy G Kaur, MW Costa, CM Nefzger, J Silva, JC Fierro-González, JM Polo, ... Nature communications 4 (1), 1637, 2013 | 91 | 2013 |
Identification of dynamic undifferentiated cell states within the male germline HM La, JA Mäkelä, AL Chan, FJ Rossello, CM Nefzger, JMD Legrand, ... Nature Communications 9 (1), 2819, 2018 | 87 | 2018 |
Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells X Sun, B Cao, M Naval-Sanchez, T Pham, YBY Sun, B Williams, ... Nature communications 12 (1), 2665, 2021 | 81 | 2021 |
Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells RDW Kelly, AE Rodda, A Dickinson, A Mahmud, CM Nefzger, W Lee, ... Stem Cells 31 (4), 703-716, 2013 | 75 | 2013 |
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium K Horvay, T Jardé, F Casagranda, VM Perreau, K Haigh, CM Nefzger, ... The EMBO journal 34 (10), 1319-1335, 2015 | 67 | 2015 |
SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program M Ratnadiwakara, SK Archer, CI Dent, I Ruiz De Los Mozos, TH Beilharz, ... Elife 7, e37419, 2018 | 61 | 2018 |
Cell type of origin dictates the route to pluripotency CM Nefzger, FJ Rossello, J Chen, X Liu, AS Knaupp, J Firas, JM Paynter, ... Cell reports 21 (10), 2649-2660, 2017 | 58 | 2017 |
TAF5L and TAF6L maintain self-renewal of embryonic stem cells via the MYC regulatory network D Seruggia, M Oti, P Tripathi, MC Canver, L LeBlanc, DC Di Giammartino, ... Molecular Cell 74 (6), 1148-1163. e7, 2019 | 49 | 2019 |
Transient naive reprogramming corrects hiPS cells functionally and epigenetically S Buckberry, X Liu, D Poppe, JP Tan, G Sun, J Chen, TV Nguyen, ... Nature 620 (7975), 863-872, 2023 | 45 | 2023 |
A versatile strategy for isolating a highly enriched population of intestinal stem cells CM Nefzger, T Jardé, FJ Rossello, K Horvay, AS Knaupp, DR Powell, ... Stem Cell Reports 6 (3), 321-329, 2016 | 40 | 2016 |
Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells CM Nefzger, CT Su, SA Fabb, BJ Hartley, SJ Beh, WR Zeng, JM Haynes, ... Stem Cells 30 (7), 1349-1361, 2012 | 37 | 2012 |