Christian Nefzger
Christian Nefzger
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A molecular roadmap of reprogramming somatic cells into iPS cells
JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ...
Cell 151 (7), 1617-1632, 2012
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes
E Mariño, JL Richards, KH McLeod, D Stanley, YA Yap, J Knight, ...
Nature immunology 18 (5), 552-562, 2017
Class-switch recombination occurs infrequently in germinal centers
JA Roco, L Mesin, SC Binder, C Nefzger, P Gonzalez-Figueroa, ...
Immunity 51 (2), 337-350. e7, 2019
A predictive computational framework for direct reprogramming between human cell types
OJL Rackham, J Firas, H Fang, ME Oates, ML Holmes, AS Knaupp, ...
Nature genetics 48 (3), 331-335, 2016
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming
X Liu, CM Nefzger, FJ Rossello, J Chen, AS Knaupp, J Firas, E Ford, ...
Nature methods 14 (11), 1055-1062, 2017
A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs
C Pflueger, D Tan, T Swain, T Nguyen, J Pflueger, C Nefzger, JM Polo, ...
Genome research 28 (8), 1193-1206, 2018
Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy
G Kaur, MW Costa, CM Nefzger, J Silva, JC Fierro-González, JM Polo, ...
Nature communications 4 (1), 1-13, 2013
Transient and permanent reconfiguration of chromatin and transcription factor occupancy drive reprogramming
AS Knaupp, S Buckberry, J Pflueger, SM Lim, E Ford, MR Larcombe, ...
Cell stem cell 21 (6), 834-845. e6, 2017
Reprogramming roadmap reveals route to human induced trophoblast stem cells
X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ...
Nature 586 (7827), 101-107, 2020
Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells
RDW Kelly, AE Rodda, A Dickinson, A Mahmud, CM Nefzger, W Lee, ...
Stem Cells 31 (4), 703-716, 2013
Identification of dynamic undifferentiated cell states within the male germline
HM La, JA Mäkelä, AL Chan, FJ Rossello, CM Nefzger, J Legrand, ...
Nature Communications 9 (1), 1-18, 2018
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium
K Horvay, T Jardé, F Casagranda, VM Perreau, K Haigh, CM Nefzger, ...
The EMBO journal 34 (10), 1319-1335, 2015
Mesenchymal niche-derived neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium
T Jardé, WH Chan, FJ Rossello, TK Kahlon, M Theocharous, TK Arackal, ...
Cell Stem Cell 27 (4), 646-662. e7, 2020
SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program
M Ratnadiwakara, SK Archer, CI Dent, IR De Los Mozos, TH Beilharz, ...
Elife 7, e37419, 2018
Cell type of origin dictates the route to pluripotency
CM Nefzger, FJ Rossello, J Chen, X Liu, AS Knaupp, J Firas, JM Paynter, ...
Cell reports 21 (10), 2649-2660, 2017
Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells
CM Nefzger, CT Su, SA Fabb, BJ Hartley, SJ Beh, WR Zeng, JM Haynes, ...
Stem Cells 30 (7), 1349-1361, 2012
A versatile strategy for isolating a highly enriched population of intestinal stem cells
CM Nefzger, T Jardé, FJ Rossello, K Horvay, AS Knaupp, DR Powell, ...
Stem Cell Reports 6 (3), 321-329, 2016
TAF5L and TAF6L maintain self-renewal of embryonic stem cells via the MYC regulatory network
D Seruggia, M Oti, P Tripathi, MC Canver, L LeBlanc, DC Di Giammartino, ...
Molecular Cell 74 (6), 1148-1163. e7, 2019
Directed expression of Gata2, Mash1, and Foxa2 synergize to induce the serotonergic neuron phenotype during in vitro differentiation of embryonic stem cells
CM Nefzger, JM Haynes, CW Pouton
Stem Cells 29 (6), 928-939, 2011
New monoclonal antibodies to defined cell surface proteins on human pluripotent stem cells
CM O'Brien, HS Chy, Q Zhou, S Blumenfeld, JW Lambshead, X Liu, J Kie, ...
Stem Cells 35 (3), 626-640, 2017
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