| Cylindrospermopsin genotoxicity and cytotoxicity: role of cytochrome P-450 and oxidative stress AR Humpage, F Fontaine, S Froscio, P Burcham, IR Falconer Journal of Toxicology and Environmental Health, Part A 68 (9), 739-753, 2005 | 242 | 2005 |
| Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products PC Burcham, LM Kaminskas, FR Fontaine, DR Petersen, SM Pyke Toxicology 181, 229-236, 2002 | 144 | 2002 |
| Pharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles F Fontaine, J Overman, M François Cell regeneration 4 (1), 1-12, 2015 | 86 | 2015 |
| VEGFD regulates blood vascular development by modulating SOX18 activity T Duong, K Koltowska, C Pichol-Thievend, L Le Guen, F Fontaine, ... Blood, The Journal of the American Society of Hematology 123 (7), 1102-1112, 2014 | 84 | 2014 |
| The antihypertensive hydralazine is an efficient scavenger of acrolein PC Burcham, PG Kerr, F Fontaine Redox Report 5 (1), 47-49, 2000 | 82 | 2000 |
| Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity PC Burcham, FR Fontaine, LM Kaminskas, DR Petersen, SM Pyke Molecular pharmacology 65 (3), 655-664, 2004 | 77 | 2004 |
| Ircinialactams: subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae W Balansa, R Islam, F Fontaine, AM Piggott, H Zhang, TI Webb, DF Gilbert, ... Bioorganic & medicinal chemistry 18 (8), 2912-2919, 2010 | 68 | 2010 |
| Role of cytochrome P450 3A in the metabolism of mefloquine in human and animal hepatocytes F Fontaine, G de Sousa, PC Burcham, P Duchene, R Rahmani Life sciences 66 (22), 2193-2212, 2000 | 64 | 2000 |
| Modulating transcription factor activity: Interfering with protein-protein interaction networks M Francois, P Donovan, F Fontaine Seminars in cell & developmental biology 99, 12-19, 2020 | 61 | 2020 |
| Cytochrome 1A1 induction by primaquine in human hepatocytes and HepG2 cells: absence of binding to the aryl hydrocarbon receptor F Fontaine, C Delescluse, G de Sousa, P Lesca, R Rahmani Biochemical pharmacology 57 (3), 255-262, 1999 | 57 | 1999 |
| Natural product libraries: assembly, maintenance, and screening. MS Butler, F Fontaine, MA Cooper Planta medica 80 (14), 1161-1170, 2014 | 54 | 2014 |
| Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator W Balansa, R Islam, DF Gilbert, F Fontaine, X Xiao, H Zhang, AM Piggott, ... Bioorganic & medicinal chemistry 21 (14), 4420-4425, 2013 | 54 | 2013 |
| Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice J Overman, F Fontaine, M Moustaqil, D Mittal, E Sierecki, N Sacilotto, ... Elife 6, e21221, 2017 | 51 | 2017 |
| Extensive protein carbonylation precedes acrolein‐mediated cell death in mouse hepatocytes PC Burcham, F Fontaine Journal of biochemical and molecular toxicology 15 (6), 309-316, 2001 | 49 | 2001 |
| Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia W Balansa, R Islam, F Fontaine, AM Piggott, H Zhang, X Xiao, TI Webb, ... Organic & biomolecular chemistry 11 (28), 4695-4701, 2013 | 48 | 2013 |
| R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma J Overman, F Fontaine, J Wylie-Sears, M Moustaqil, L Huang, M Meurer, ... Elife 8, e43026, 2019 | 45 | 2019 |
| Small-Molecule Inhibitors of the SOX18 Transcription Factor F Fontaine, J Overman, M Moustaqil, S Mamidyala, A Salim, ... Cell Chemical Biology 24 (3), 346-359, 2017 | 44 | 2017 |
| A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor Z Dekan, S Sianati, A Yousuf, KJ Sutcliffe, A Gillis, C Mallet, P Singh, ... Proceedings of the National Academy of Sciences 116 (44), 22353-22358, 2019 | 40 | 2019 |
| Effects of macrolide antibiotics on CYP3A expression in human and rat hepatocytes: interspecies differences in response to troleandomycin N Ledirac, G de Sousa, F Fontaine, C Agouridas, J Gugenheim, ... Drug metabolism and disposition 28 (12), 1391-1393, 2000 | 33 | 2000 |
| Non–beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma CT Seebauer, MS Graus, L Huang, A McCann, J Wylie-Sears, F Fontaine, ... The Journal of clinical investigation 132 (3), 2022 | 32 | 2022 |
Philip BurchamAssociate Professor of Pharmacology & Toxicology, University of Western AustraliaVerified email at uwa.edu.au
