Rowena Martin
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Chloroquine transport via the malaria parasite’s chloroquine resistance transporter
RE Martin, RV Marchetti, AI Cowan, SM Howitt, S Bröer, K Kirk
science 325 (5948), 1680-1682, 2009
Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance
PG Bray, RE Martin, L Tilley, SA Ward, K Kirk, DA Fidock
Molecular microbiology 56 (2), 323-333, 2005
The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily
RE Martin, K Kirk
Molecular biology and evolution 21 (10), 1938-1949, 2004
Functional profiling of a Plasmodium genome reveals an abundance of essential genes
E Bushell, AR Gomes, T Sanderson, B Anar, G Girling, C Herd, T Metcalf, ...
Cell 170 (2), 260-272. e8, 2017
The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum
RE Martin, RI Henry, JL Abbey, JD Clements, K Kirk
Genome biology 6 (3), R26, 2005
Transport of the essential nutrient isoleucine in human erythrocytes infected with the malaria parasite Plasmodium falciparum
RE Martin, K Kirk
Blood 109 (5), 2217-2224, 2007
Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies
MI Veiga, SK Dhingra, PP Henrich, J Straimer, N Gnädig, AC Uhlemann, ...
Nature communications 7 (1), 1-12, 2016
Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite
KJ Saliba, RE Martin, A Bröer, RI Henry, CS McCarthy, MJ Downie, ...
Nature 443 (7111), 582-585, 2006
Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics
RL Summers, MN Nash, RE Martin
Cellular and Molecular Life Sciences 69 (12), 1967-1995, 2012
Membrane transport proteins of the malaria parasite
RE Martin, H Ginsburg, K Kirk
Molecular microbiology 74 (3), 519-528, 2009
Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum …
VK Zishiri, MC Joshi, R Hunter, K Chibale, PJ Smith, RL Summers, ...
Journal of medicinal chemistry 54 (19), 6956-6968, 2011
Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter
RL Summers, A Dave, TJ Dolstra, S Bellanca, RV Marchetti, MN Nash, ...
Proceedings of the National Academy of Sciences 111 (17), E1759-E1767, 2014
Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents
S Gemma, C Camodeca, M Brindisi, S Brogi, G Kukreja, S Kunjir, ...
Journal of medicinal chemistry 55 (23), 10387-10404, 2012
Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite’s food vacuole and alter drug sensitivities
S Pulcini, HM Staines, AH Lee, SH Shafik, G Bouyer, CM Moore, ...
Scientific reports 5 (1), 1-16, 2015
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure–activity relationships, in vivo studies, and preliminary toxicity profiling
S Gemma, C Camodeca, S Sanna Coccone, BP Joshi, M Bernetti, ...
Journal of medicinal chemistry 55 (15), 6948-6967, 2012
A lactate and formate transporter in the intraerythrocytic malaria parasite, Plasmodium falciparum
RV Marchetti, AM Lehane, SH Shafik, M Winterberg, RE Martin, K Kirk
Nature communications 6 (1), 1-7, 2015
Transport properties of the host cell membrane
K Kirk, HM Staines, RE Martin, KJ Saliba
Novartis Foundation Symposium, 55-73, 1999
Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites
S Bellanca, RL Summers, M Meyrath, A Dave, MN Nash, M Dittmer, ...
Journal of Biological Chemistry 289 (52), 36336-36351, 2014
Quinine Dimers Are Potent Inhibitors of the Plasmodium falciparum Chloroquine Resistance Transporter and Are Active against Quinoline-Resistant P. falciparum
CA Hrycyna, RL Summers, AM Lehane, MM Pires, H Namanja, K Bohn, ...
ACS chemical biology 9 (3), 722-730, 2014
Methionine transport in the malaria parasite Plasmodium falciparum
SA Cobbold, RE Martin, K Kirk
International journal for parasitology 41 (1), 125-135, 2011
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