| Design, synthesis, and evaluation of multitarget-directed resveratrol derivatives for the treatment of Alzheimer’s disease C Lu, Y Guo, J Yan, Z Luo, HB Luo, M Yan, L Huang, X Li Journal of Medicinal Chemistry 56 (14), 5843-5859, 2013 | 252 | 2013 |
| Synthesis and evaluation of multi-target-directed ligands against Alzheimer’s disease based on the fusion of donepezil and ebselen Z Luo, J Sheng, Y Sun, C Lu, J Yan, A Liu, H Luo, L Huang, X Li Journal of medicinal chemistry 56 (22), 9089-9099, 2013 | 181 | 2013 |
| Multitarget-directed benzylideneindanone derivatives: anti-β-amyloid (Aβ) aggregation, antioxidant, metal chelation, and monoamine oxidase B (MAO-B) inhibition properties … L Huang, C Lu, Y Sun, F Mao, Z Luo, T Su, H Jiang, W Shan, X Li Journal of medicinal chemistry 55 (19), 8483-8492, 2012 | 163 | 2012 |
| Benzenediol-berberine hybrids: Multifunctional agents for Alzheimer’s disease H Jiang, X Wang, L Huang, Z Luo, T Su, K Ding, X Li Bioorganic & medicinal chemistry 19 (23), 7228-7235, 2011 | 101 | 2011 |
| Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids L Huang, T Su, W Shan, Z Luo, Y Sun, F He, X Li Bioorganic & medicinal chemistry 20 (9), 3038-3048, 2012 | 94 | 2012 |
| Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase L Huang, Z Luo, F He, J Lu, X Li Bioorganic & medicinal chemistry 18 (12), 4475-4484, 2010 | 84 | 2010 |
| O-Hydroxyl-or o-amino benzylamine-tacrine hybrids: Multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation F Mao, L Huang, Z Luo, A Liu, C Lu, Z Xie, X Li Bioorganic & medicinal chemistry 20 (19), 5884-5892, 2012 | 79 | 2012 |
| Syntheses and in vitro evaluation of new S1PR1 compounds and initial evaluation of a lead F-18 radiotracer in rodents Z Luo, AJ Rosenberg, H Liu, J Han, Z Tu European journal of medicinal chemistry 150, 796-808, 2018 | 78 | 2018 |
| Synthesis and biological evaluation of a new series of ebselen derivatives as glutathione peroxidase (GPx) mimics and cholinesterase inhibitors against Alzheimer’s disease Z Luo, L Liang, J Sheng, Y Pang, J Li, L Huang, X Li Bioorganic & medicinal chemistry 22 (4), 1355-1361, 2014 | 70 | 2014 |
| Novel tacrine–ebselen hybrids with improved cholinesterase inhibitory, hydrogen peroxide and peroxynitrite scavenging activity F Mao, J Chen, Q Zhou, Z Luo, L Huang, X Li Bioorganic & medicinal chemistry letters 23 (24), 6737-6742, 2013 | 69 | 2013 |
| Berberine derivatives, with substituted amino groups linked at the 9-position, as inhibitors of acetylcholinesterase/butyrylcholinesterase L Huang, Z Luo, F He, A Shi, F Qin, X Li Bioorganic & medicinal chemistry letters 20 (22), 6649-6652, 2010 | 49 | 2010 |
| PET imaging study of S1PR1 expression in a rat model of multiple sclerosis H Liu, H Jin, X Yue, Z Luo, C Liu, AJ Rosenberg, Z Tu Molecular imaging and biology 18, 724-732, 2016 | 44 | 2016 |
| The Ru-catalyzed enantioselective preparation of chiral halohydrins and their application in the synthesis of (R)-clorprenaline and (S)-sotalol C Lu, Z Luo, L Huang, X Li Tetrahedron: Asymmetry 22 (7), 722-727, 2011 | 37 | 2011 |
| Dual β2-adrenoceptor agonists-PDE4 inhibitors for the treatment of asthma and COPD WJ Shan, L Huang, Q Zhou, HL Jiang, ZH Luo, K Lai, XS Li Bioorganic & medicinal chemistry letters 22 (4), 1523-1526, 2012 | 33 | 2012 |
| Hybrids consisting of the pharmacophores of salmeterol and roflumilast or phthalazinone: dual β2-adrenoceptor agonists-PDE4 inhibitors for the treatment of COPD A Liu, L Huang, Z Wang, Z Luo, F Mao, W Shan, J Xie, K Lai, X Li Bioorganic & medicinal chemistry letters 23 (5), 1548-1552, 2013 | 24 | 2013 |
| An efficient and promising method to prepare Ladostigil (TV3326) via asymmetric transfer hydrogenation catalyzed by Ru–Cs-DPEN in an HCOONa–H2O–surfactant system Z Luo, F Qin, S Yan, X Li Tetrahedron: Asymmetry 23 (5), 333-338, 2012 | 24 | 2012 |
| Computer-assisted designed “selenoxy–chinolin”: a new catalytic mechanism of the GPx-like cycle and inhibition of metal-free and metal-associated Aβ aggregation Z Wang, Y Wang, W Li, Z Liu, Z Luo, Y Sun, R Wu, L Huang, X Li Dalton Transactions 44 (48), 20913-20925, 2015 | 18 | 2015 |
| In vivo Characterization of Four 18F-Labeled S1PR1 Tracers for Neuroinflammation H Liu, Z Luo, J Gu, H Jiang, S Joshi, KI Shoghi, Y Zhou, RJ Gropler, ... Molecular imaging and biology 22, 1362-1369, 2020 | 17 | 2020 |
| Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation X Yue, DD Dhavale, J Li, Z Luo, J Liu, H Yang, RH Mach, PT Kotzbauer, ... Bioorganic & medicinal chemistry letters 28 (6), 1011-1019, 2018 | 17 | 2018 |
| Design, synthesis, and in vitro bioactivity evaluation of fluorine-containing analogues for sphingosine-1-phosphate 2 receptor Z Luo, H Liu, RS Klein, Z Tu Bioorganic & medicinal chemistry 27 (16), 3619-3631, 2019 | 12 | 2019 |
