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Jun Huang
Jun Huang
Verified email at uchicago.edu - Homepage
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Cited by
Year
T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition
E Hui, J Cheung, J Zhu, X Su, MJ Taylor, HA Wallweber, DK Sasmal, ...
Science 355 (6332), 1428-1433, 2017
15222017
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
J Huang, VI Zarnitsyna, B Liu, LJ Edwards, N Jiang, BD Evavold, C Zhu
Nature 464 (7290), 932-936, 2010
5792010
A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4+ T cells
J Huang, M Brameshuber, X Zeng, J Xie, Q Li, Y Chien, S Valitutti, ...
Immunity 39 (5), 846-857, 2013
3872013
γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response
X Zeng, YL Wei, J Huang, EW Newell, H Yu, BA Kidd, MS Kuhns, ...
Immunity 37 (3), 524-534, 2012
2212012
Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination
N Jiang, J Huang, LJ Edwards, B Liu, Y Zhang, CD Beal, BD Evavold, ...
Immunity 34 (1), 13-23, 2011
1942011
High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+ T cell responses
JJ Sabatino Jr, J Huang, C Zhu, BD Evavold
Journal of Experimental Medicine 208 (1), 81-90, 2011
1922011
Antigen-presenting cell-intrinsic PD-1 neutralizes PD-L1 in cis to attenuate PD-1 signaling in T cells
Y Zhao, DL Harrison, Y Song, J Ji, J Huang, E Hui
Cell reports 24 (2), 379-390. e6, 2018
1682018
A self-illuminating nanoparticle for inflammation imaging and cancer therapy
X Xu, H An, D Zhang, H Tao, Y Dou, X Li, J Huang, J Zhang
Science advances 5 (1), eaat2953, 2019
1612019
Quantifying the effects of molecular orientation and length on two-dimensional receptor-ligand binding kinetics
J Huang, J Chen, SE Chesla, T Yago, P Mehta, RP McEver, C Zhu, ...
Journal of Biological Chemistry 279 (43), 44915-44923, 2004
1542004
CD8+ T cells and NK cells: parallel and complementary soldiers of immunotherapy
J Rosenberg, J Huang
Current opinion in chemical engineering 19, 9-20, 2018
1382018
A proresolving peptide nanotherapy for site‐specific treatment of inflammatory bowel disease by regulating proinflammatory microenvironment and gut microbiota
C Li, Y Zhao, J Cheng, J Guo, Q Zhang, X Zhang, J Ren, F Wang, J Huang, ...
Advanced science 6 (18), 1900610, 2019
1362019
Kinetics of MHC-CD8 interaction at the T cell membrane
J Huang, LJ Edwards, BD Evavold, C Zhu
The Journal of Immunology 179 (11), 7653-7662, 2007
1222007
Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer
J Huang, X Zeng, N Sigal, PJ Lund, LF Su, H Huang, Y Chien, MM Davis
Proceedings of the National Academy of Sciences 113 (13), E1890-E1897, 2016
1122016
Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets
HL Dugan, CT Stamper, L Li, S Changrob, NW Asby, PJ Halfmann, ...
Immunity 54 (6), 1290-1303. e7, 2021
1112021
Single-molecule fluorescence resonance energy transfer in molecular biology
DK Sasmal, LE Pulido, S Kasal, J Huang
Nanoscale 8 (48), 19928-19944, 2016
1072016
Measuring receptor–ligand binding kinetics on cell surfaces: from adhesion frequency to thermal fluctuation methods
W Chen, VI Zarnitsyna, KK Sarangapani, J Huang, C Zhu
Cellular and molecular bioengineering 1, 276-288, 2008
1012008
Cyclodextrin‐derived intrinsically bioactive nanoparticles for treatment of acute and chronic inflammatory diseases
J Guo, D Li, H Tao, G Li, R Liu, Y Dou, T Jin, L Li, J Huang, H Hu, J Zhang
Advanced Materials 31 (46), 1904607, 2019
842019
Insights from in situ analysis of TCR–pMHC recognition: response of an interaction network
C Zhu, N Jiang, J Huang, VI Zarnitsyna, BD Evavold
Immunological reviews 251 (1), 49-64, 2013
842013
Memory in receptor–ligand-mediated cell adhesion
VI Zarnitsyna, J Huang, F Zhang, YH Chien, D Leckband, C Zhu
Proceedings of the National Academy of Sciences 104 (46), 18037-18042, 2007
692007
T-cell mechanobiology: force sensation, potentiation, and translation
DL Harrison, Y Fang, J Huang
Frontiers in physics 7, 45, 2019
642019
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Articles 1–20