Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization JH Reed, J Jackson, D Christ, CC Goodnow Journal of Experimental Medicine 213 (7), 1255-1265, 2016 | 160 | 2016 |
Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination DL Burnett, DB Langley, P Schofield, JR Hermes, TD Chan, J Jackson, ... Science 360 (6385), 223-226, 2018 | 140 | 2018 |
B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle S Rizzetto, DNP Koppstein, J Samir, M Singh, JH Reed, CH Cai, AR Lloyd, ... Bioinformatics 34 (16), 2846-2847, 2018 | 100 | 2018 |
Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody M Singh, KJL Jackson, JJ Wang, P Schofield, MA Field, D Koppstein, ... Cell 180 (5), 878-894. e19, 2020 | 92 | 2020 |
IgD attenuates the IgM-induced anergy response in transitional and mature B cells Z Sabouri, S Perotti, E Spierings, P Humburg, M Yabas, H Bergmann, ... Nature communications 7 (1), 13381, 2016 | 81 | 2016 |
A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block D Alvarez, P Briassouli, RM Clancy, J Zavadil, JH Reed, RG Abellar, ... Journal of Biological Chemistry 286 (35), 30444-30454, 2011 | 80 | 2011 |
DNA hypermethylation encroachment at CpG island borders in cancer is predisposed by H3K4 monomethylation patterns K Skvortsova, E Masle-Farquhar, PL Luu, JZ Song, W Qu, E Zotenko, ... Cancer cell 35 (2), 297-314. e8, 2019 | 77 | 2019 |
Ro60 requires Y3 RNA for cell surface exposure and inflammation associated with cardiac manifestations of neonatal lupus JH Reed, S Sim, SL Wolin, RM Clancy, JP Buyon The Journal of Immunology 191 (1), 110-116, 2013 | 57 | 2013 |
Different temporal expression of immunodominant Ro60/60 kDa-SSA and La/SSB apotopes JH Reed, PJ Neufing, MW Jackson, RM Clancy, PJ Macardle, JP Buyon, ... Clinical & Experimental Immunology 148 (1), 153-160, 2007 | 57 | 2007 |
Complement Receptor 3 Influences Toll-like Receptor 7/8-Dependent Inflammation JH Reed, M Jain, K Lee, ER Kandimalla, MH Faridi, JP Buyon, V Gupta, ... Journal of Biological Chemistry 288 (13), 9077-9083, 2013 | 56 | 2013 |
Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity DL Burnett, JH Reed, D Christ, CC Goodnow Immunological reviews 292 (1), 61-75, 2019 | 55 | 2019 |
Umbilical cord blood levels of maternal antibodies reactive with p200 and full‐length Ro 52 in the assessment of risk for cardiac manifestations of neonatal lupus JH Reed, RM Clancy, KH Lee, A Saxena, PM Izmirly, JP Buyon Arthritis care & research 64 (9), 1373-1381, 2012 | 49 | 2012 |
Ro 60 functions as a receptor for β2‐glycoprotein I on apoptotic cells JH Reed, B Giannakopoulos, MW Jackson, SA Krilis, TP Gordon Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 44 | 2009 |
AB cell apotope of Ro 60 in systemic lupus erythematosus JH Reed, MW Jackson, TP Gordon Arthritis & Rheumatism 58 (4), 1125-1129, 2008 | 42 | 2008 |
B cell apotopes of the 60-kDa Ro/SSA and La/SSB autoantigens JH Reed, MW Jackson, TP Gordon Journal of Autoimmunity 31 (3), 263-267, 2008 | 41 | 2008 |
Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production A Lau, DT Avery, K Jackson, H Lenthall, S Volpi, H Brigden, AJ Russell, ... Journal of Experimental Medicine 217 (2), 2020 | 38 | 2020 |
Pathogenicity and proteomic signatures of autoantibodies to Ro and La R Lindop, G Arentz, LA Thurgood, JH Reed, MW Jackson, TP Gordon Immunology and Cell Biology 90 (3), 304-309, 2012 | 38 | 2012 |
An autoantibody in narcolepsy disrupts colonic migrating motor complexes MW Jackson, JH Reed, AJF Smith, TP Gordon Journal of Neuroscience 28 (49), 13303-13309, 2008 | 36 | 2008 |
β2-Glycoprotein I and Protection from Anti-SSA/Ro60–Associated Cardiac Manifestations of Neonatal Lupus JH Reed, RM Clancy, AW Purcell, MY Kim, TP Gordon, JP Buyon The Journal of Immunology 187 (1), 520-526, 2011 | 35 | 2011 |
Molecular signature of a public clonotypic autoantibody in primary Sjögren's syndrome: A “forbidden” clone in systemic autoimmunity R Lindop, G Arentz, TK Chataway, LA Thurgood, MW Jackson, JH Reed, ... Arthritis & Rheumatism 63 (11), 3477-3486, 2011 | 29 | 2011 |