| The non‐immunosuppressive cyclosporin DEBIO‐025 is a potent inhibitor of hepatitis C virus replication in vitro J Paeshuyse, A Kaul, E De Clercq, B Rosenwirth, JM Dumont, P Scalfaro, ... Hepatology 43 (4), 761-770, 2006 | 343 | 2006 |
| DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A L Coelmont, X Hanoulle, U Chatterji, C Berger, J Snoeck, M Bobardt, ... PloS one 5 (10), e13687, 2010 | 216 | 2010 |
| Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically … L Coelmont, S Kaptein, J Paeshuyse, I Vliegen, JM Dumont, G Vuagniaux, ... Antimicrobial agents and chemotherapy 53 (3), 967-976, 2009 | 153 | 2009 |
| Ribavirin for the treatment of chronic hepatitis C virus infection: a review of the proposed mechanisms of action J Paeshuyse, K Dallmeier, J Neyts Current opinion in virology 1 (6), 590-598, 2011 | 148 | 2011 |
| Statins potentiate the in vitro anti‐hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development L Delang, J Paeshuyse, I Vliegen, P Leyssen, S Obeid, D Durantel, ... Hepatology 50 (1), 6-16, 2009 | 139 | 2009 |
| Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus P Roelandt, S Obeid, J Paeshuyse, J Vanhove, A Van Lommel, ... Journal of hepatology 57 (2), 246-251, 2012 | 122 | 2012 |
| Mechanistic characterization of GS-9190 (Tegobuvir), a novel nonnucleoside inhibitor of hepatitis C virus NS5B polymerase I Shih, I Vliegen, B Peng, H Yang, C Hebner, J Paeshuyse, G Pürstinger, ... Antimicrobial agents and chemotherapy 55 (9), 4196-4203, 2011 | 107 | 2011 |
| Synthesis and primary antiviral activity evaluation of 3-hydrazono-5-nitro-2-indolinone derivatives N Terzioglu, N Karali, A Gursoy, C Pannecouque, P Leysen, J Paeshuyse, ... Arkivoc 1 (109-118), 2006 | 104 | 2006 |
| Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: From anti-pestivirus to anti-hepatitis C virus activity G Puerstinger, J Paeshuyse, E De Clercq, J Neyts Bioorganic & medicinal chemistry letters 17 (2), 390-393, 2007 | 101 | 2007 |
| Synthesis and Anti-BVDV Activity of Acridones As New Potential Antiviral Agents 1 O Tabarrini, G Manfroni, A Fravolini, V Cecchetti, S Sabatini, E De Clercq, ... Journal of medicinal chemistry 49 (8), 2621-2627, 2006 | 100 | 2006 |
| Synthesis and antiviral activity of an imidazo[1,2-a]pyrrolo[2,3-c]pyridine series against the bovine viral diarrhea virus JM Chezal, J Paeshuyse, V Gaumet, D Canitrot, A Maisonial, C Lartigue, ... European journal of medicinal chemistry 45 (5), 2044-2047, 2010 | 91 | 2010 |
| The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication L Delang, J Paeshuyse, J Neyts Biochemical pharmacology 84 (11), 1400-1408, 2012 | 89 | 2012 |
| Ribavirin antagonizes the in vitro anti-hepatitis C virus activity of 2′-C-methylcytidine, the active component of valopicitabine L Coelmont, J Paeshuyse, MP Windisch, E De Clercq, R Bartenschlager, ... Antimicrobial agents and chemotherapy 50 (10), 3444-3446, 2006 | 88 | 2006 |
| A novel highly selective inhibitor of pestivirus replication that targets the viral RNA dependent RNA polymerase J Paeshuyse, P Leyssen, E Mabery, N Boddeker, R Donis, IH Ansari, ... Antiviral Research 62 (2), A84-A85, 2004 | 87 | 2004 |
| A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase J Paeshuyse, P Leyssen, E Mabery, N Boddeker, R Vrancken, M Froeyen, ... Journal of virology 80 (1), 149-160, 2006 | 85 | 2006 |
| Interferons, interferon inducers, and interferon-ribavirin in treatment of flavivirus-induced encephalitis in mice P Leyssen, C Drosten, M Paning, N Charlier, J Paeshuyse, E De Clercq, ... Antimicrobial agents and chemotherapy 47 (2), 777-782, 2003 | 84 | 2003 |
| A multifaceted study of Pseudomonas aeruginosa shutdown by virulent podovirus LUZ19 R Lavigne, E Lecoutere, J Wagemans, W Cenens, A Aertsen, L Schoofs, ... MBio 4 (2), e00061-13, 2013 | 83 | 2013 |
| A multifaceted study of R Lavigne, E Lecoutere, J Wagemans, W Cenens, A Aertsen, L Schoofs, ... Pseudomonas aeruginosa, 00061-13, 2013 | 83* | 2013 |
| Hemin potentiates the anti-hepatitis C virus activity of the antimalarial drug artemisinin J Paeshuyse, L Coelmont, I Vliegen, J Vandenkerckhove, E Peys, B Sas, ... Biochemical and biophysical research communications 348 (1), 139-144, 2006 | 73 | 2006 |
| Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor G Manfroni, J Paeshuyse, S Massari, S Zanoli, B Gatto, G Maga, ... Journal of medicinal chemistry 52 (10), 3354-3365, 2009 | 64 | 2009 |
