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Zhenyao Luo
Zhenyao Luo
Verified email at uq.edu.au
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Year
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration
MD Figley, W Gu, JD Nanson, Y Shi, Y Sasaki, K Cunnea, AK Malde, X Jia, ...
Neuron 109 (7), 1118-1136. e11, 2021
1972021
Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae
SL Begg, BA Eijkelkamp, Z Luo, RM Counago, JR Morey, MJ Maher, ...
Nature communications 6 (1), 6418, 2015
1252015
An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis
TM Ryan, J Trewhella, JM Murphy, JR Keown, L Casey, FG Pearce, ...
Journal of applied crystallography 51 (1), 97-111, 2018
772018
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules
Y Shi, PS Kerry, JD Nanson, T Bosanac, Y Sasaki, R Krauss, FK Saikot, ...
Molecular cell 82 (9), 1643-1659. e10, 2022
712022
Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ...
Elife 10, e72823, 2021
292021
Molecular basis of regio-and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines
C Sun, Z Luo, W Zhang, W Tian, H Peng, Z Lin, Z Deng, B Kobe, X Jia, ...
Nature Communications 11 (1), 6251, 2020
292020
Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach
M Bajaj, SK Mamidyala, J Zuegg, SL Begg, MP Ween, Z Luo, JX Huang, ...
ACS chemical biology 10 (6), 1511-1520, 2015
262015
Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB
SJ Hancock, MD Phan, Z Luo, AW Lo, KM Peters, NTK Nhu, BM Forde, ...
Nature Microbiology 5 (11), 1340-1348, 2020
222020
Potent activation of SARM1 by NMN analogue VMN underlies vacor neurotoxicity
A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ...
BioRxiv, 2020.09. 18.304261, 2020
152020
Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nat Commun 6: 6418
SL Begg, BA Eijkelkamp, Z Luo, RM Couñago, JR Morey, MJ Maher, ...
132015
A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA
Z Luo, JR Morey, E Deplazes, A Motygullina, A Tan, K Ganio, SL Neville, ...
Mbio 12 (1), 10.1128/mbio. 01958-20, 2021
122021
Structure and Metal Binding Properties of Chlamydia trachomatis YtgA
Z Luo, SL Neville, R Campbell, JR Morey, S Menon, M Thomas, ...
Journal of Bacteriology 202 (1), 10.1128/jb. 00580-19, 2019
122019
Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake in Streptococcus pneumoniae
ML Župan, Z Luo, K Ganio, VG Pederick, SL Neville, E Deplazes, B Kobe, ...
Frontiers in Cellular and Infection Microbiology 11, 729981, 2021
102021
Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes
MA Struwe, P Kalimuthu, Z Luo, Q Zhong, D Ellis, J Yang, KC Khadanand, ...
Journal of Biological Chemistry 296, 2021
82021
Heterogeneous nucleation is required for crystallization of the ZnuA domain of pneumococcal AdcA
Z Luo, JR Morey, CA McDevitt, B Kobe
Acta Crystallographica Section F: Structural Biology Communications 71 (12 …, 2015
62015
AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans
MSI Wizrah, SMH Chua, Z Luo, MK Manik, M Pan, JML Whyte, ...
Journal of Biological Chemistry 298 (10), 2022
52022
The impact of chromate on Pseudomonas aeruginosa molybdenum homeostasis
EA Maunders, DHY Ngu, K Ganio, SI Hossain, BYJ Lim, MG Leeming, ...
Frontiers in Microbiology 13, 903146, 2022
52022
Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing
W Gu, Z Luo, C Vonrhein, X Jia, T Ve, JD Nanson, B Kobe
Acta Crystallographica Section F: Structural Biology Communications 77 (10 …, 2021
42021
Structural characterisation of the HT3 motif of the polyhistidine triad protein D from Streptococcus pneumoniae
Z Luo, VG Pederick, JC Paton, CA McDevitt, B Kobe
FEBS letters 592 (13), 2341-2350, 2018
42018
Structural and biochemical characterization of Acinetobacter baumannii ZnuA
S Alquethamy, K Ganio, Z Luo, SI Hossain, AJ Hayes, T Ve, MR Davies, ...
Journal of Inorganic Biochemistry 231, 111787, 2022
32022
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