SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration MD Figley, W Gu, JD Nanson, Y Shi, Y Sasaki, K Cunnea, AK Malde, X Jia, ... Neuron 109 (7), 1118-1136. e11, 2021 | 197 | 2021 |
Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae SL Begg, BA Eijkelkamp, Z Luo, RM Counago, JR Morey, MJ Maher, ... Nature communications 6 (1), 6418, 2015 | 125 | 2015 |
An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis TM Ryan, J Trewhella, JM Murphy, JR Keown, L Casey, FG Pearce, ... Journal of applied crystallography 51 (1), 97-111, 2018 | 77 | 2018 |
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules Y Shi, PS Kerry, JD Nanson, T Bosanac, Y Sasaki, R Krauss, FK Saikot, ... Molecular cell 82 (9), 1643-1659. e10, 2022 | 71 | 2022 |
Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1 A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ... Elife 10, e72823, 2021 | 29 | 2021 |
Molecular basis of regio-and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines C Sun, Z Luo, W Zhang, W Tian, H Peng, Z Lin, Z Deng, B Kobe, X Jia, ... Nature Communications 11 (1), 6251, 2020 | 29 | 2020 |
Discovery of novel pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach M Bajaj, SK Mamidyala, J Zuegg, SL Begg, MP Ween, Z Luo, JX Huang, ... ACS chemical biology 10 (6), 1511-1520, 2015 | 26 | 2015 |
Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB SJ Hancock, MD Phan, Z Luo, AW Lo, KM Peters, NTK Nhu, BM Forde, ... Nature Microbiology 5 (11), 1340-1348, 2020 | 22 | 2020 |
Potent activation of SARM1 by NMN analogue VMN underlies vacor neurotoxicity A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ... BioRxiv, 2020.09. 18.304261, 2020 | 15 | 2020 |
Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nat Commun 6: 6418 SL Begg, BA Eijkelkamp, Z Luo, RM Couñago, JR Morey, MJ Maher, ... | 13 | 2015 |
A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA Z Luo, JR Morey, E Deplazes, A Motygullina, A Tan, K Ganio, SL Neville, ... Mbio 12 (1), 10.1128/mbio. 01958-20, 2021 | 12 | 2021 |
Structure and Metal Binding Properties of Chlamydia trachomatis YtgA Z Luo, SL Neville, R Campbell, JR Morey, S Menon, M Thomas, ... Journal of Bacteriology 202 (1), 10.1128/jb. 00580-19, 2019 | 12 | 2019 |
Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake in Streptococcus pneumoniae ML Župan, Z Luo, K Ganio, VG Pederick, SL Neville, E Deplazes, B Kobe, ... Frontiers in Cellular and Infection Microbiology 11, 729981, 2021 | 10 | 2021 |
Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes MA Struwe, P Kalimuthu, Z Luo, Q Zhong, D Ellis, J Yang, KC Khadanand, ... Journal of Biological Chemistry 296, 2021 | 8 | 2021 |
Heterogeneous nucleation is required for crystallization of the ZnuA domain of pneumococcal AdcA Z Luo, JR Morey, CA McDevitt, B Kobe Acta Crystallographica Section F: Structural Biology Communications 71 (12 …, 2015 | 6 | 2015 |
AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans MSI Wizrah, SMH Chua, Z Luo, MK Manik, M Pan, JML Whyte, ... Journal of Biological Chemistry 298 (10), 2022 | 5 | 2022 |
The impact of chromate on Pseudomonas aeruginosa molybdenum homeostasis EA Maunders, DHY Ngu, K Ganio, SI Hossain, BYJ Lim, MG Leeming, ... Frontiers in Microbiology 13, 903146, 2022 | 5 | 2022 |
Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing W Gu, Z Luo, C Vonrhein, X Jia, T Ve, JD Nanson, B Kobe Acta Crystallographica Section F: Structural Biology Communications 77 (10 …, 2021 | 4 | 2021 |
Structural characterisation of the HT3 motif of the polyhistidine triad protein D from Streptococcus pneumoniae Z Luo, VG Pederick, JC Paton, CA McDevitt, B Kobe FEBS letters 592 (13), 2341-2350, 2018 | 4 | 2018 |
Structural and biochemical characterization of Acinetobacter baumannii ZnuA S Alquethamy, K Ganio, Z Luo, SI Hossain, AJ Hayes, T Ve, MR Davies, ... Journal of Inorganic Biochemistry 231, 111787, 2022 | 3 | 2022 |