| Phase-plate cryo-EM structure of a class B GPCR–G-protein complex YL Liang, M Khoshouei, M Radjainia, Y Zhang, A Glukhova, J Tarrasch, ... Nature 546 (7656), 118-123, 2017 | 481 | 2017 |
| Structure of the adenosine-bound human adenosine A 1 receptor–G i complex CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ... Nature 558 (7711), 559-563, 2018 | 320 | 2018 |
| Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex YL Liang, M Khoshouei, A Glukhova, SGB Furness, P Zhao, L Clydesdale, ... Nature 555 (7694), 121-125, 2018 | 298 | 2018 |
| Beyond mere markers: functions for CD34 family of sialomucins in hematopoiesis SGB Furness, K McNagny Immunologic research 34, 13-32, 2006 | 183 | 2006 |
| Receptor activity-modifying proteins differentially modulate the G protein-coupling efficiency of amylin receptors M Morfis, N Tilakaratne, SGB Furness, G Christopoulos, TD Werry, ... Endocrinology 149 (11), 5423-5431, 2008 | 146 | 2008 |
| The extracellular surface of the GLP-1 receptor is a molecular trigger for biased agonism D Wootten, CA Reynolds, KJ Smith, JC Mobarec, C Koole, EE Savage, ... Cell 165 (7), 1632-1643, 2016 | 144 | 2016 |
| Activation of the GLP-1 receptor by a non-peptidic agonist P Zhao, YL Liang, MJ Belousoff, G Deganutti, MM Fletcher, FS Willard, ... Nature 577 (7790), 432-436, 2020 | 131 | 2020 |
| Ligand-dependent modulation of G protein conformation alters drug efficacy SGB Furness, YL Liang, CJ Nowell, ML Halls, PJ Wookey, E Dal Maso, ... Cell 167 (3), 739-749. e11, 2016 | 126 | 2016 |
| Differential GLP-1R binding and activation by peptide and non-peptide agonists X Zhang, MJ Belousoff, P Zhao, AJ Kooistra, TT Truong, SY Ang, ... Molecular Cell 80 (3), 485-500. e7, 2020 | 120 | 2020 |
| The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors SGB Furness, MJ Lees, ML Whitelaw FEBS letters 581 (19), 3616-3625, 2007 | 107 | 2007 |
| Dominant negative G proteins enhance formation and purification of agonist-GPCR-G protein complexes for structure determination YL Liang, P Zhao, C Draper-Joyce, JA Baltos, A Glukhova, TT Truong, ... ACS Pharmacology & Translational Science 1 (1), 12-20, 2018 | 92 | 2018 |
| Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP‐1R activation K Pabreja, MA Mohd, C Koole, D Wootten, SGB Furness British journal of pharmacology 171 (5), 1114-1128, 2014 | 87 | 2014 |
| Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics AE Cook, SN Mistry, KJ Gregory, SGB Furness, PM Sexton, PJ Scammells, ... British journal of pharmacology 172 (1), 185-200, 2015 | 86 | 2015 |
| Recent advances in understanding GLP-1R (glucagon-like peptide-1 receptor) function C Koole, K Pabreja, EE Savage, D Wootten, SGB Furness, LJ Miller, ... Biochemical Society Transactions 41 (1), 172-179, 2013 | 85 | 2013 |
| Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity … YL Liang, MJ Belousoff, MM Fletcher, X Zhang, M Khoshouei, G Deganutti, ... ACS Pharmacology & Translational Science, 2020 | 73 | 2020 |
| The pleiotropy of dioxin toxicity—Xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles SGB Furness, F Whelan Pharmacology & therapeutics 124 (3), 336-353, 2009 | 72 | 2009 |
| Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allostery KG Harikumar, D Wootten, DI Pinon, C Koole, AM Ball, SGB Furness, ... Proceedings of the National Academy of Sciences 109 (45), 18607-18612, 2012 | 71 | 2012 |
| A hydrogen-bonded polar network in the core of the glucagon-like peptide-1 receptor is a fulcrum for biased agonism: lessons from class B crystal structures D Wootten, CA Reynolds, C Koole, KJ Smith, JC Mobarec, J Simms, ... Molecular pharmacology 89 (3), 335-347, 2016 | 70 | 2016 |
| Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias KV Andreassen, ST Hjuler, SG Furness, PM Sexton, A Christopoulos, ... PloS one 9 (3), e92042, 2014 | 70 | 2014 |
| Small molecule allosteric modulation of the glucagon-like peptide-1 receptor enhances the insulinotropic effect of oxyntomodulin FS Willard, D Wootten, AD Showalter, EE Savage, J Ficorilli, TB Farb, ... Molecular pharmacology 82 (6), 1066-1073, 2012 | 70 | 2012 |
Denise WoottenMonash Institute of Pharmaceutical SciencesVerified email at monash.edu
