The 4 Å X-ray structure of a tubulin: stathmin-like domain complex B Gigant, PA Curmi, C Martin-Barbey, E Charbaut, S Lachkar, L Lebeau, ... Cell 102 (6), 809-816, 2000 | 324 | 2000 |
S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression DA Skoufias, S DeBonis, Y Saoudi, L Lebeau, I Crevel, R Cross, ... Journal of biological chemistry 281 (26), 17559-17569, 2006 | 303 | 2006 |
In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities S Debonis, DA Skoufias, L Lebeau, R Lopez, G Robin, RL Margolis, ... Molecular cancer therapeutics 3 (9), 1079-1090, 2004 | 274 | 2004 |
Interaction of the mitotic inhibitor monastrol with human kinesin Eg5 S DeBonis, JP Simorre, I Crevel, L Lebeau, DA Skoufias, A Blangy, ... Biochemistry 42 (2), 338-349, 2003 | 239 | 2003 |
New chemical tools for investigating human mitotic kinesin Eg5 E Klein, S DeBonis, B Thiede, DA Skoufias, F Kozielski, L Lebeau Bioorganic & medicinal chemistry 15 (19), 6474-6488, 2007 | 180 | 2007 |
Efficient in vitro and in vivo pulmonary delivery of nucleic acid by carbon dot-based nanocarriers P Pierrat, R Wang, D Kereselidze, M Lux, P Didier, A Kichler, F Pons, ... Biomaterials 51, 290-302, 2015 | 169 | 2015 |
Dimeric surfactants: first synthesis of an asymmetrical gemini compound P Renouf, C Mioskowski, L Lebeau, D Hebrault, JR Desmurs Tetrahedron Letters 39 (11), 1357-1360, 1998 | 110 | 1998 |
Molecular organization of bovine rod cGMP-phosphodiesterase 6 JFK Tcheudji, L Lebeau, N Virmaux, CG Maftei, RH Cote, C Lugnier, ... Journal of molecular biology 310 (4), 781-791, 2001 | 109 | 2001 |
Ligand-and DNA-induced dissociation of RXR tetramers ZP Chen, J Iyer, W Bourguet, P Held, C Mioskowski, L Lebeau, N Noy, ... Journal of molecular biology 275 (1), 55-65, 1998 | 89 | 1998 |
Two-dimensional crystallization of a membrane protein on a detergent-resistant lipid monolayer L Lebeau, F Lach, C Vénien-Bryan, A Renault, J Dietrich, T Jahn, ... Journal of molecular biology 308 (4), 639-647, 2001 | 88 | 2001 |
Long-range attraction between nucleosides with short-range specificity: Direct measurements F Pincet, E Perez, G Bryant, L Lebeau, C Mioskowski Physical review letters 73 (20), 2780, 1994 | 88 | 1994 |
Density of surface charge is a more predictive factor of the toxicity of cationic carbon nanoparticles than zeta potential M Weiss, J Fan, M Claudel, T Sonntag, P Didier, C Ronzani, L Lebeau, ... Journal of nanobiotechnology 19, 1-19, 2021 | 79 | 2021 |
Synthesis of New Phospholipids Linked to Steroid‐Hormone Derivatives Designed for Two‐Dimensional Crystallization of Proteins L Lebeau, P Oudet, C Mioskowski Helvetica chimica acta 74 (8), 1697-1706, 1991 | 73 | 1991 |
Selective monodeprotection of phosphate, phosphite, phosphonate, and phosphoramide benzyl esters M Saady, L Lebeau, C Mioskowski The Journal of Organic Chemistry 60 (9), 2946-2947, 1995 | 70 | 1995 |
Synthesis and surface-active properties of a series of new anionic gemini compounds P Renouf, D Hebrault, JR Desmurs, JM Mercier, C Mioskowski, L Lebeau Chemistry and Physics of Lipids 99 (1), 21-32, 1999 | 63 | 1999 |
Hydrolysis and Hydrogenolysis of Formamidines: N,N-Dimethyl and N,N-Dibenzyl Formamidines as Protective Groups for Primary Amines S Vincent, C Mioskowski, L Lebeau The Journal of Organic Chemistry 64 (3), 991-997, 1999 | 58 | 1999 |
First Use of Benzyl Phosphites in the Michaelis‐Arbuzov Reaction synthesis of mono‐, Di‐, and triphosphate analogs M Saady, L Lebeau, C Mioskowski Helvetica chimica acta 78 (3), 670-678, 1995 | 55 | 1995 |
Development of a direct assay for measuring intracellular AZT triphosphate in humans peripheral blood mononuclear cells F Becher, D Schlemmer, A Pruvost, MC Nevers, C Goujard, S Jorajuria, ... Analytical chemistry 74 (16), 4220-4227, 2002 | 52 | 2002 |
“HFP” fluorinated cationic lipids for enhanced lipoplex stability and gene delivery E Klein, M Ciobanu, J Klein, V Machi, C Leborgne, T Vandamme, B Frisch, ... Bioconjugate chemistry 21 (2), 360-371, 2010 | 49 | 2010 |
Three-dimensional model of Escherichia coli gyrase B subunit crystallized in two-dimensions on novobiocin-linked phospholipid films H Celia, L Hoermann, P Schultz, L Lebeau, V Mallouh, DB Wigley, ... Journal of molecular biology 236 (2), 618-628, 1994 | 49 | 1994 |