| Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol JP Schaller, D Keller, L Poget, P Pratte, E Kaelin, D McHugh, G Cudazzo, ... Regulatory Toxicology and Pharmacology 81, S27-S47, 2016 | 385 | 2016 |
| Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation D McHugh, R Flemming, SZ Xu, AL Perraud, DJ Beech Journal of Biological Chemistry 278 (13), 11002-11006, 2003 | 321 | 2003 |
| Upregulated TRPC1 channel in vascular injury in vivo and its role in human neointimal hyperplasia B Kumar, K Dreja, SS Shah, A Cheong, SZ Xu, P Sukumar, J Naylor, ... Circulation research 98 (4), 557-563, 2006 | 244 | 2006 |
| A Sphingosine-1–phosphate-activated calcium channel controlling vascular smooth muscle cell motility SZ Xu, K Muraki, F Zeng, J Li, P Sukumar, S Shah, AM Dedman, ... Circulation research 98 (11), 1381-1389, 2006 | 177 | 2006 |
| Inhibition of cardiac L-type calcium channels by protein kinase C phosphorylation of two sites in the N-terminal domain D McHugh, EM Sharp, T Scheuer, WA Catterall Proceedings of the National Academy of Sciences 97 (22), 12334-12338, 2000 | 173 | 2000 |
| TRPC1 store-operated cationic channel subunit DJ Beech, SZ Xu, D McHugh, R Flemming Cell calcium 33 (5-6), 433-440, 2003 | 156 | 2003 |
| Human TRPC5 channel activated by a multiplicity of signals in a single cell F Zeng, SZ Xu, PK Jackson, D McHugh, B Kumar, SJ Fountain, DJ Beech The Journal of physiology 559 (3), 739-750, 2004 | 155 | 2004 |
| Calcium‐sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowth H Hui, D McHugh, M Hannan, F Zeng, SZ Xu, SH Khan, R Levenson, ... The Journal of physiology 572 (1), 165-172, 2006 | 120 | 2006 |
| Modulation of Ca2+ channel activity by ATP metabolism and internal Mg2+ in guinea‐pig basilar artery smooth muscle cells. D McHugh, DJ Beech The Journal of Physiology 492 (2), 359-376, 1996 | 39 | 1996 |
| Block of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A S Surah‐Narwal, SZ Xu, D McHugh, RL McDonald, E Hough, A Cheong, ... British journal of pharmacology 128 (3), 667-672, 1999 | 37 | 1999 |
| An electrophysiological characterization of naturally occurring tobacco alkaloids and their action on human α4β2 and α7 nicotinic acetylcholine receptors O Alijevic, D McHugh, L Rufener, A Mazurov, J Hoeng, M Peitsch Phytochemistry 170, 112187, 2020 | 26 | 2020 |
| Lysosomotropic-related limitations of the BALB/c 3T3 cell-based neutral red uptake assay and an alternative testing approach for assessing e-liquid cytotoxicity G Cudazzo, DJ Smart, D McHugh, P Vanscheeuwijck Toxicology In Vitro 61, 104647, 2019 | 24 | 2019 |
| Protein kinase C requirement of Ca2+ channel stimulation by intracellular ATP in guinea‐pig basilar artery smooth muscle cells. D McHugh, DJ Beech The Journal of Physiology 500 (2), 311-317, 1997 | 20 | 1997 |
| Inhibition of delayed rectifier K+‐current by levcromakalim in single intestinal smooth muscle cells: effects of cations and dependence on K+‐flux D McHugh, DJ Beech British journal of pharmacology 114 (2), 391-399, 1995 | 19 | 1995 |
| Development of an integrated assay in human TK6 cells to permit comprehensive genotoxicity analysis in vitro DJ Smart, FR Helbling, M Verardo, A Huber, D McHugh, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 849, 503129, 2020 | 16 | 2020 |
| Mode‐of‐action analysis of the effects induced by nicotine in the in vitro micronucleus assay DJ Smart, FR Helbling, M Verardo, D McHugh, P Vanscheeuwijck Environmental and Molecular Mutagenesis 60 (9), 778-791, 2019 | 12 | 2019 |
| Evidence that TASK1 channels contribute to the background current in AH/type II neurons of the guinea-pig intestine H Matsuyama, TV Nguyen, B Hunne, M Thacker, K Needham, D McHugh, ... Neuroscience 155 (3), 738-750, 2008 | 11 | 2008 |
| Xu SZ, McHugh D, and Flemming R DJ Beech TRPC1 store-operated cationic channel subunit. Cell Calcium 33, 433-440, 2003 | 7 | 2003 |
| Workshop Series to Identify, Discuss, and Develop Recommendations for the Optimal Generation and Use of In Vitro Assay Data for Tobacco Product Evaluation … MM Moore, J Clements, P Desai, U Doshi, M Gaca, X Guo, T Hashizume, ... Applied in vitro Toxicology 6 (2), 49-63, 2020 | 6 | 2020 |
| Sharp EM, Scheuer T, Catterall WA D McHugh Inhibition of cardiac L-type calcium channels by protein kinase C …, 2000 | 6 | 2000 |
