| Spontaneous Inward Opening of the Dopamine Transporter Is Triggered by PIP2-Regulated Dynamics of the N-Terminus G Khelashvili, N Stanley, MA Sahai, J Medina, MV LeVine, L Shi, ... ACS chemical neuroscience 6 (11), 1825-1837, 2015 | 106 | 2015 |
| NbIT-a new information theory-based analysis of allosteric mechanisms reveals residues that underlie function in the leucine transporter LeuT MV LeVine, H Weinstein PLoS computational biology 10 (5), e1003603, 2014 | 98 | 2014 |
| Ligand modulation of sidechain dynamics in a wild-type human GPCR LD Clark, I Dikiy, K Chapman, KEJ Rödström, J Aramini, MV LeVine, ... Elife 6, e28505, 2017 | 87 | 2017 |
| A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2 JM Perez-Aguilar, J Shan, MV LeVine, G Khelashvili, H Weinstein Journal of the American Chemical Society 136 (45), 16044-16054, 2014 | 87 | 2014 |
| Allosteric mechanisms of molecular machines at the membrane: transport by sodium-coupled symporters MV LeVine, MA Cuendet, G Khelashvili, H Weinstein Chemical reviews 116 (11), 6552-6587, 2016 | 75 | 2016 |
| A new computational method for membrane compressibility: Bilayer mechanical thickness revisited M Doktorova, MV LeVine, G Khelashvili, H Weinstein Biophysical journal 116 (3), 487-502, 2019 | 67 | 2019 |
| Computational approaches to detect allosteric pathways in transmembrane molecular machines S Stolzenberg, M Michino, MV LeVine, H Weinstein, L Shi Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (7), 1652-1662, 2016 | 61 | 2016 |
| A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport DS Terry, RA Kolster, M Quick, MV LeVine, G Khelashvili, Z Zhou, ... Nature communications 9 (1), 230, 2018 | 41 | 2018 |
| Molecular dynamics simulations related to Sars-Cov-2 DE Shaw DE Shaw Research Technical Data, 2020 | 39 | 2020 |
| X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release K Gotfryd, T Boesen, JS Mortensen, G Khelashvili, M Quick, DS Terry, ... Nature Communications 11 (1), 1005, 2020 | 36 | 2020 |
| The membrane protein LeuT in micellar systems: aggregation dynamics and detergent binding to the S2 site G Khelashvili, MV LeVine, L Shi, M Quick, JA Javitch, H Weinstein Journal of the American Chemical Society 135 (38), 14266-14275, 2013 | 34 | 2013 |
| The allostery landscape: Quantifying thermodynamic couplings in biomolecular systems MA Cuendet, H Weinstein, MV LeVine Biophysical Journal 112 (3), 354a, 2017 | 32 | 2017 |
| Development of force field parameters for the simulation of single-and double-stranded DNA molecules and DNA–protein complexes MR Tucker, S Piana, D Tan, MV LeVine, DE Shaw The Journal of Physical Chemistry B 126 (24), 4442-4457, 2022 | 31 | 2022 |
| The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor MV LeVine, DS Terry, G Khelashvili, ZS Siegel, M Quick, JA Javitch, ... Proceedings of the National Academy of Sciences 116 (32), 15947-15956, 2019 | 22 | 2019 |
| AIM for allostery: using the Ising model to understand information processing and transmission in allosteric biomolecular systems MV LeVine, H Weinstein Entropy 17 (5), 2895-2918, 2015 | 22 | 2015 |
| Thermodynamic coupling function analysis of allosteric mechanisms in the human dopamine transporter MV LeVine, MA Cuendet, AM Razavi, G Khelashvili, H Weinstein Biophysical Journal 114 (1), 10-14, 2018 | 16 | 2018 |
| Role of annular lipids in the functional properties of leucine transporter LeuT proteomicelles MV LeVine, G Khelashvili, L Shi, M Quick, JA Javitch, H Weinstein Biochemistry 55 (6), 850-859, 2016 | 14 | 2016 |
| N-body information theory (NbIT) analysis of rigid-body dynamics in intracellular loop 2 of the 5-HT2A receptor MV LeVine, JM Perez-Aguilar, H Weinstein arXiv preprint arXiv:1406.4730, 2014 | 9 | 2014 |
| The allosteric mechanism leading to an open-groove lipid conductive state of the TMEM16F scramblase G Khelashvili, E Kots, X Cheng, MV Levine, H Weinstein Communications Biology 5 (1), 990, 2022 | 8 | 2022 |
| Effects of dextromethorphan on zebrafish larval development F Scalzo, M Levine Neurotoxicology and Teratology 4 (31), 250, 2009 | 1 | 2009 |
Harel WeinsteinProfessor of Professor of Physiology and Biophysics, Weill Cornell Medicine, Cornell U.Verified email at med.cornell.edu
