The human secretome M Uhlén, MJ Karlsson, A Hober, AS Svensson, J Scheffel, D Kotol, ... Science signaling 12 (609), eaaz0274, 2019 | 374 | 2019 |
Evolution from adherent to suspension: systems biology of HEK293 cell line development M Malm, R Saghaleyni, M Lundqvist, M Giudici, V Chotteau, R Field, ... Scientific reports 10 (1), 18996, 2020 | 103 | 2020 |
Combining phage and staphylococcal surface display for generation of ErbB3-specific Affibody molecules N Kronqvist, M Malm, L Göstring, E Gunneriusson, M Nilsson, ... Protein Engineering, Design & Selection 24 (4), 385-396, 2011 | 98 | 2011 |
Inhibiting HER3-mediated tumor cell growth with affibody molecules engineered to low picomolar affinity by position-directed error-prone PCR-like diversification M Malm, N Kronqvist, H Lindberg, L Gudmundsdotter, T Bass, FY Frejd, ... Plos one 8 (5), e62791, 2013 | 89 | 2013 |
Engineering of a bispecific affibody molecule towards HER2 and HER3 by addition of an albumin‐binding domain allows for affinity purification and in vivo half‐life extension M Malm, T Bass, L Gudmundsdotter, M Lord, FY Frejd, S Ståhl, J Löfblom Biotechnology journal 9 (9), 1215-1222, 2014 | 73 | 2014 |
Small-scale bioreactor supports high density HEK293 cell perfusion culture for the production of recombinant Erythropoietin H Schwarz, Y Zhang, C Zhan, M Malm, R Field, R Turner, C Sellick, ... Journal of Biotechnology 309, 44-52, 2020 | 61 | 2020 |
Imaging of HER3-expressing xenografts in mice using a 99mTc(CO)3-HEHEHE-ZHER3:08699 affibody molecule A Orlova, M Malm, M Rosestedt, Z Varasteh, K Andersson, RK Selvaraju, ... European journal of nuclear medicine and molecular imaging 41, 1450-1459, 2014 | 61 | 2014 |
Cellular effects of HER3-specific affibody molecules L Göstring, M Malm, I Höidén-Guthenberg, FY Frejd, S Ståhl, J Löfblom, ... PloS one 7 (6), e40023, 2012 | 59 | 2012 |
Targeting HER3 using mono-and bispecific antibodies or alternative scaffolds M Malm, FY Frejd, S Ståhl, J Löfblom MAbs 8 (7), 1195-1209, 2016 | 56 | 2016 |
Low shear stress increases recombinant protein production and high shear stress increases apoptosis in human cells C Zhan, G Bidkhori, H Schwarz, M Malm, A Mebrahtu, R Field, C Sellick, ... IScience 23 (11), 2020 | 37 | 2020 |
Comparative evaluation of 111In-labeled NOTA‑conjugated affibody molecules for visualization of HER3 expression in malignant tumors KG Andersson, M Rosestedt, Z Varasteh, M Malm, M Sandström, ... Oncology Reports 34 (2), 1042-1048, 2015 | 37 | 2015 |
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins M Malm, CC Kuo, MM Barzadd, A Mebrahtu, N Wistbacka, R Razavi, ... Metabolic engineering 72, 171-187, 2022 | 28 | 2022 |
Staphylococcal surface display in combinatorial protein engineering and epitope mapping of antibodies N Kronqvist, M Malm, J Rockberg, B Hjelm, M Uhlén, S Stahl, J Lofblom Recent Patents on Biotechnology 4 (3), 171-182, 2010 | 25 | 2010 |
The human secretome–the proteins secreted from human cells M Uhlen, H Tegel, Å Sivertsson, CC Kuo, JM Gutierrez, NE Lewis, ... BioRxiv, 465815, 2018 | 16 | 2018 |
Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells R Saghaleyni, M Malm, N Moruzzi, J Zrimec, R Razavi, N Wistbacka, ... Cell reports 39 (11), 2022 | 11 | 2022 |
Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells MM Barzadd, M Lundqvist, C Harris, M Malm, AL Volk, N Thalén, ... New Biotechnology 68, 68-76, 2022 | 8 | 2022 |
Display of a naïve affibody library on staphylococci for selection of binders by means of flow cytometry sorting CD Leitao, AM Borras, A Jonsson, M Malm, N Kronqvist, F Fleetwood, ... Biochemical and Biophysical Research Communications 655, 75-81, 2023 | 3 | 2023 |
Author Correction: Evolution from adherent to suspension: systems biology of HEK293 cell line development M Malm, R Saghaleyni, M Lundqvist, M Giudici, V Chotteau, R Field, ... Scientific Reports 11 (1), 5407, 2021 | 3 | 2021 |
HER3 binding polypeptides M Malm, J Löfblom, S Ståhl US Patent 9,745,350, 2017 | 3 | 2017 |
Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold NB Thalén, MM Barzadd, M Lundqvist, J Rodhe, M Andersson, G Bidkhori, ... Metabolic engineering 81, 157-166, 2024 | 2 | 2024 |