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Magdalena Malm
Magdalena Malm
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The human secretome
M Uhlén, MJ Karlsson, A Hober, AS Svensson, J Scheffel, D Kotol, ...
Science signaling 12 (609), eaaz0274, 2019
3742019
Evolution from adherent to suspension: systems biology of HEK293 cell line development
M Malm, R Saghaleyni, M Lundqvist, M Giudici, V Chotteau, R Field, ...
Scientific reports 10 (1), 18996, 2020
1032020
Combining phage and staphylococcal surface display for generation of ErbB3-specific Affibody molecules
N Kronqvist, M Malm, L Göstring, E Gunneriusson, M Nilsson, ...
Protein Engineering, Design & Selection 24 (4), 385-396, 2011
982011
Inhibiting HER3-mediated tumor cell growth with affibody molecules engineered to low picomolar affinity by position-directed error-prone PCR-like diversification
M Malm, N Kronqvist, H Lindberg, L Gudmundsdotter, T Bass, FY Frejd, ...
Plos one 8 (5), e62791, 2013
892013
Engineering of a bispecific affibody molecule towards HER2 and HER3 by addition of an albumin‐binding domain allows for affinity purification and in vivo half‐life extension
M Malm, T Bass, L Gudmundsdotter, M Lord, FY Frejd, S Ståhl, J Löfblom
Biotechnology journal 9 (9), 1215-1222, 2014
732014
Small-scale bioreactor supports high density HEK293 cell perfusion culture for the production of recombinant Erythropoietin
H Schwarz, Y Zhang, C Zhan, M Malm, R Field, R Turner, C Sellick, ...
Journal of Biotechnology 309, 44-52, 2020
612020
Imaging of HER3-expressing xenografts in mice using a 99mTc(CO)3-HEHEHE-ZHER3:08699 affibody molecule
A Orlova, M Malm, M Rosestedt, Z Varasteh, K Andersson, RK Selvaraju, ...
European journal of nuclear medicine and molecular imaging 41, 1450-1459, 2014
612014
Cellular effects of HER3-specific affibody molecules
L Göstring, M Malm, I Höidén-Guthenberg, FY Frejd, S Ståhl, J Löfblom, ...
PloS one 7 (6), e40023, 2012
592012
Targeting HER3 using mono-and bispecific antibodies or alternative scaffolds
M Malm, FY Frejd, S Ståhl, J Löfblom
MAbs 8 (7), 1195-1209, 2016
562016
Low shear stress increases recombinant protein production and high shear stress increases apoptosis in human cells
C Zhan, G Bidkhori, H Schwarz, M Malm, A Mebrahtu, R Field, C Sellick, ...
IScience 23 (11), 2020
372020
Comparative evaluation of 111In-labeled NOTA‑conjugated affibody molecules for visualization of HER3 expression in malignant tumors
KG Andersson, M Rosestedt, Z Varasteh, M Malm, M Sandström, ...
Oncology Reports 34 (2), 1042-1048, 2015
372015
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins
M Malm, CC Kuo, MM Barzadd, A Mebrahtu, N Wistbacka, R Razavi, ...
Metabolic engineering 72, 171-187, 2022
282022
Staphylococcal surface display in combinatorial protein engineering and epitope mapping of antibodies
N Kronqvist, M Malm, J Rockberg, B Hjelm, M Uhlén, S Stahl, J Lofblom
Recent Patents on Biotechnology 4 (3), 171-182, 2010
252010
The human secretome–the proteins secreted from human cells
M Uhlen, H Tegel, Å Sivertsson, CC Kuo, JM Gutierrez, NE Lewis, ...
BioRxiv, 465815, 2018
162018
Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells
R Saghaleyni, M Malm, N Moruzzi, J Zrimec, R Razavi, N Wistbacka, ...
Cell reports 39 (11), 2022
112022
Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells
MM Barzadd, M Lundqvist, C Harris, M Malm, AL Volk, N Thalén, ...
New Biotechnology 68, 68-76, 2022
82022
Display of a naïve affibody library on staphylococci for selection of binders by means of flow cytometry sorting
CD Leitao, AM Borras, A Jonsson, M Malm, N Kronqvist, F Fleetwood, ...
Biochemical and Biophysical Research Communications 655, 75-81, 2023
32023
Author Correction: Evolution from adherent to suspension: systems biology of HEK293 cell line development
M Malm, R Saghaleyni, M Lundqvist, M Giudici, V Chotteau, R Field, ...
Scientific Reports 11 (1), 5407, 2021
32021
HER3 binding polypeptides
M Malm, J Löfblom, S Ståhl
US Patent 9,745,350, 2017
32017
Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold
NB Thalén, MM Barzadd, M Lundqvist, J Rodhe, M Andersson, G Bidkhori, ...
Metabolic engineering 81, 157-166, 2024
22024
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