Reactive oxygen species enhance insulin sensitivity K Loh, H Deng, A Fukushima, X Cai, B Boivin, S Galic, C Bruce, ... Cell metabolism 10 (4), 260-272, 2009 | 665 | 2009 |
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers CG Fedele, LM Ooms, M Ho, J Vieusseux, SA O'Toole, EK Millar, ... Proceedings of the National Academy of Sciences 107 (51), 22231-22236, 2010 | 319 | 2010 |
The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease LM Ooms, KA Horan, P Rahman, G Seaton, R Gurung, DS Kethesparan, ... Biochemical Journal 419 (1), 29-49, 2009 | 268 | 2009 |
The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin JM Dyson, CJ O'Malley, J Becanovic, AD Munday, MC Berndt, ID Coghill, ... The Journal of cell biology 155 (6), 1065-1080, 2001 | 181 | 2001 |
A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9) J Sun, L Ooms, CH Bird, VR Sutton, JA Trapani, PI Bird Journal of Biological Chemistry 272 (24), 15434-15441, 1997 | 142 | 1997 |
Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1: localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and … S Brown, MJ McGrath, LM Ooms, R Gurung, MM Maimone, CA Mitchell Journal of Biological Chemistry 274 (38), 27083-27091, 1999 | 119 | 1999 |
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization: the inositol 5-phosphatase SKIP localizes to … R Gurung, A Tan, LM Ooms, MJ McGrath, RD Huysmans, AD Munday, ... Journal of Biological Chemistry 278 (13), 11376-11385, 2003 | 116 | 2003 |
Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network AM Kong, CJ Speed, CJ O'Malley, MJ Layton, T Meehan, KL Loveland, ... Journal of Biological Chemistry 275 (31), 24052-24064, 2000 | 116 | 2000 |
Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases SJ Rodgers, DT Ferguson, CA Mitchell, LM Ooms Bioscience reports 37 (1), BSR20160432, 2017 | 114 | 2017 |
The inositol polyphosphate 5-phosphatase PIPP regulates AKT1-dependent breast cancer growth and metastasis LM Ooms, LC Binge, EM Davies, P Rahman, JRW Conway, R Gurung, ... Cancer cell 28 (2), 155-169, 2015 | 110 | 2015 |
The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis JC Whisstock, S Romero, R Gurung, H Nandurkar, LM Ooms, ... Journal of Biological Chemistry 275 (47), 37055-37061, 2000 | 92 | 2000 |
The inositol polyphosphate 5-phosphatase, PIPP, is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation LM Ooms, CG Fedele, MV Astle, I Ivetac, V Cheung, RB Pearson, ... Molecular biology of the cell 17 (2), 607-622, 2006 | 87 | 2006 |
The inositol polyphosphate 5-phosphatases: traffic controllers, waistline watchers and tumour suppressors? MV Astle, KA Horan, LM Ooms, CA Mitchell Biochemical Society Symposia 74, 161-181, 2007 | 70 | 2007 |
Inositol polyphosphate 5‐phosphatases: lipid phosphatases with flair CA Mitchell, R Gurung, AM Kong, JM Dyson, A Tan, LM Ooms Iubmb Life 53 (1), 25-36, 2002 | 61 | 2002 |
The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4, 5 … LM Ooms, BK McColl, F Wiradjaja, APW Wijayaratnam, P Gleeson, ... Molecular and Cellular Biology 20 (24), 9376-9390, 2000 | 58 | 2000 |
Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML S Rijal, S Fleming, N Cummings, NK Rynkiewicz, LM Ooms, NYN Nguyen, ... Blood, The Journal of the American Society of Hematology 125 (18), 2815-2824, 2015 | 56 | 2015 |
The phosphatidylinositol (3, 4, 5)-trisphosphate-dependent Rac exchanger 1· Ras-related C3 botulinum toxin substrate 1 (P-Rex1· Rac1) complex reveals the basis of Rac1 … CM Lucato, ML Halls, LM Ooms, HJ Liu, CA Mitchell, JC Whisstock, ... Journal of Biological Chemistry 290 (34), 20827-20840, 2015 | 55 | 2015 |
P-Rex1–a multidomain protein that regulates neurite differentiation JAE Waters, MV Astle, LM Ooms, D Balamatsias, R Gurung, CA Mitchell Journal of cell science 121 (17), 2892-2903, 2008 | 53 | 2008 |
P-Rex1 and P-Rex2 RacGEFs and cancer N Srijakotre, J Man, LM Ooms, CM Lucato, AM Ellisdon, CA Mitchell Biochemical Society Transactions 45 (4), 963-977, 2017 | 45 | 2017 |
A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart SSM Manji, LH Williams, KA Miller, LM Ooms, M Bahlo, CA Mitchell, ... PLoS One 6 (3), e17607, 2011 | 45 | 2011 |