Alexandre Escargueil
Alexandre Escargueil
Sorbonne Université
Verified email at inserm.fr
TitleCited byYear
Catalytic topoisomerase II inhibitors in cancer therapy
AK Larsen, AE Escargueil, A Skladanowski
Pharmacology & therapeutics 99 (2), 167-181, 2003
4282003
Resistance mechanisms associated with altered intracellular distribution of anticancer agents
AK Larsen, AE Escargueil, A Skladanowski
Pharmacology & therapeutics 85 (3), 217-229, 2000
4262000
The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane
A Garrigues, AE Escargueil, S Orlowski
Proceedings of the National Academy of Sciences 99 (16), 10347-10352, 2002
2242002
Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743
DG Soares, AE Escargueil, V Poindessous, A Sarasin, A de Gramont, ...
Proceedings of the National Academy of Sciences 104 (32), 13062-13067, 2007
1762007
P-glycoprotein and ‘lipid rafts’: some ambiguous mutual relationships (floating on them, building them or meeting them by chance?)
S Orlowski, S Martin, A Escargueil
Cellular and Molecular Life Sciences CMLS 63 (9), 1038-1059, 2006
1212006
PARPs and the DNA damage response
FG Sousa, R Matuo, DG Soares, AE Escargueil, JAP Henriques, ...
Carcinogenesis 33 (8), 1433-1440, 2012
1172012
What histone code for DNA repair?
AE Escargueil, DG Soares, M Salvador, AK Larsen, JAP Henriques
Mutation Research/Reviews in Mutation Research 658 (3), 259-270, 2008
1082008
Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors
A Lorz, T Lorenzi, J Clairambault, A Escargueil, B Perthame
Bulletin of mathematical biology 77 (1), 1-22, 2015
872015
Mitotic phosphorylation of DNA topoisomerase II α by protein kinase CK2 creates the MPM-2 phosphoepitope on Ser-1469
AE Escargueil, SY Plisov, O Filhol, C Cochet, AK Larsen
Journal of Biological Chemistry 275 (44), 34710-34718, 2000
842000
Molecular cross-talk between the transcription, translation, and nonsense-mediated decay machineries
FJ Iborra, AE Escargueil, KY Kwek, A Akoulitchev, PR Cook
Journal of cell science 117 (6), 899-906, 2004
762004
Emergence of drug tolerance in cancer cell populations: an evolutionary outcome of selection, nongenetic instability, and stress-induced adaptation
RH Chisholm, T Lorenzi, A Lorz, AK Larsen, LN de Almeida, A Escargueil, ...
Cancer research 75 (6), 930-939, 2015
692015
From DNA damage to G~ 2 arrest: the many roles of topoisomerase II
AK Larsen, AE Escargeuil, A Skladanowski
PROGRESS IN CELL CYCLE RESEARCH. 5, 295-300, 2003
642003
Trabectedin and its C subunit modified analogue PM01183 attenuate nucleotide excision repair and show activity toward platinum-resistant cells
DG Soares, MS Machado, CJ Rocca, V Poindessous, D Ouaret, A Sarasin, ...
Molecular cancer therapeutics 10 (8), 1481-1489, 2011
622011
5‐Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line
R Matuo, FG Sousa, AE Escargueil, I Grivicich, D Garcia‐Santos, ...
Journal of Applied Toxicology 29 (4), 308-316, 2009
542009
EGFR-and VEGF (R)-targeted small molecules show synergistic activity in colorectal cancer models refractory to combinations of monoclonal antibodies
V Poindessous, D Ouaret, K El Ouadrani, A Battistella, VF Mégalophonos, ...
Clinical Cancer Research 17 (20), 6522-6530, 2011
522011
Intrinsic bevacizumab resistance is associated with prolonged activation of autocrine VEGF signaling and hypoxia tolerance in colorectal cancer cells and can be overcome by …
P Mésange, V Poindessous, M Sabbah, AE Escargueil, A de Gramont, ...
Oncotarget 5 (13), 4709, 2014
512014
Saccharomyces cerevisiae as a model system to study the response to anticancer agents
R Matuo, FG Sousa, DG Soares, D Bonatto, J Saffi, AE Escargueil, ...
Cancer chemotherapy and pharmacology 70 (4), 491-502, 2012
512012
Recruitment of cdc2 kinase by DNA topoisomerase II is coupled to chromatin remodeling
AE Escargueil, SY Plisov, A Skladanowski, A Borgne, L Meijer, ...
The FASEB Journal 15 (12), 2288-2290, 2001
352001
DNA repair pathways involved in repair of lesions induced by 5-fluorouracil and its active metabolite FdUMP
R Matuo, FG Sousa, AE Escargueil, DG Soares, I Grivicich, J Saffi, ...
Biochemical pharmacology 79 (2), 147-153, 2010
342010
Influence of irofulven, a transcription-coupled repair-specific antitumor agent, on RNA polymerase activity, stability and dynamics in living mammalian cells
AE Escargueil, V Poindessous, DG Soares, A Sarasin, PR Cook, ...
Journal of cell science 121 (8), 1275-1283, 2008
342008
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