c-Abl mediated tyrosine phosphorylation of Aha1 activates its co-chaperone function in cancer cells DM Dunn, MR Woodford, AW Truman, SM Jensen, J Schulman, T Caza, ... Cell reports 12 (6), 1006-1018, 2015 | 63 | 2015 |
Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors H Zhao, G Garg, J Zhao, E Moroni, A Girgis, LS Franco, S Singh, ... European journal of medicinal chemistry 89, 442-466, 2015 | 47 | 2015 |
Identification of LASSBio-1945 as an inhibitor of SARS-CoV-2 main protease (M PRO) through in silico screening supported by molecular docking and a fragment-based pharmacophore … LS Franco, RC Maia, EJ Barreiro RSC medicinal chemistry 12 (1), 110-119, 2021 | 18 | 2021 |
Chemical intuition in drug design and discovery JGB Pedreira, LS Franco, EJ Barreiro Current topics in medicinal chemistry 19 (19), 1679-1693, 2019 | 18 | 2019 |
Synthesis of 1,4‐Anthracene‐9,10‐dione Derivatives and Their Regulation of Nitric Oxide, IL‐1β and TNF‐α in Activated RAW264.7 Cells TA Corrêa, CCS Alves, SBR Castro, EE Oliveira, LS Franco, AP Ferreira, ... Chemical Biology & Drug Design 82 (4), 463-467, 2013 | 9 | 2013 |
The Magic Methyl and Its Tricks in Drug Discovery and Development PSM Pinheiro, LS Franco, CAM Fraga Pharmaceuticals 16 (8), 1157, 2023 | 6 | 2023 |
Novel phosphatidylinositol 4-kinases III beta (PI4KIIIβ) inhibitors discovered by virtual screening using free energy models NM Colodette, LS Franco, RC Maia, HH Fokoue, CMR Sant’Anna, ... Journal of Computer-Aided Molecular Design 34, 1091-1103, 2020 | 5 | 2020 |
Discovery of Putative Dual Inhibitor of Tubulin and EGFR by Phenotypic Approach on LASSBio-1586 Homologs G Barbosa, LGV Gelves, CMX Costa, LS Franco, JAL de Lima, ... Pharmaceuticals 15 (8), 913, 2022 | 3 | 2022 |
LASSBio Chemical Library Diversity and FLT3 New Ligand Identification LS Franco, RC Maia, EJ Barreiro Journal of the Brazilian Chemical Society 35 (10), e-20240059, 2024 | | 2024 |
Molecular hybridization: a powerful tool for multitarget drug discovery P de Sena Murteira Pinheiro, LS Franco, TL Montagnoli, CAM Fraga Expert Opinion on Drug Discovery 19 (4), 451-470, 2024 | | 2024 |
Stereochemical insights into β-amino-N-acylhydrazones and their impact on DPP-4 inhibition E Reina, LS Franco, TR Carneiro, EJ Barreiro, LM Lima RSC advances 14 (10), 6617-6626, 2024 | | 2024 |
LASSBio Chemical Library: molecular properties profile and repurposing studies LS Franco, R do Maia, EJ Barreiro Galoá, 2022 | | 2022 |