| Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity RJ Mortishire-Smith, GL Skiles, JW Lawrence, S Spence, AW Nicholls, ... Chemical research in toxicology 17 (2), 165-173, 2004 | 177 | 2004 |
| Identification of TNO155, an allosteric SHP2 inhibitor for the treatment of cancer MJ LaMarche, M Acker, A Argintaru, D Bauer, J Boisclair, H Chan, ... Journal of medicinal chemistry 63 (22), 13578-13594, 2020 | 130 | 2020 |
| The heart rate-corrected QT interval of conscious beagle dogs: a formula based on analysis of covariance S Spence, K Soper, CM Hoe, J Coleman Toxicological Sciences 45 (2), 247-258, 1998 | 129 | 1998 |
| An autoradiographic analysis of neurogenesis in the chick retinain vitro andin vivo SG Spence, JA Robson Neuroscience 32 (3), 801-812, 1989 | 111 | 1989 |
| Fibulin is localized at sites of epithelial-mesenchymal transitions in the early avian embryo SG Spence, WS Argraves, L Walters, JE Hungerford, CD Little Developmental biology 151 (2), 473-484, 1992 | 95 | 1992 |
| Defining the susceptible period of developmental toxicity for the AT1‐selective angiotensin II receptor antagonist Losartan in rats SG Spence, HL Allen, MA Cukierski, JM Manson, RT Robertson, ... Teratology 51 (6), 367-382, 1995 | 91 | 1995 |
| 6-Amino-3-methylpyrimidinones as potent, selective, and orally efficacious SHP2 inhibitors P Sarver, M Acker, JT Bagdanoff, Z Chen, YN Chen, H Chan, B Firestone, ... Journal of medicinal chemistry 62 (4), 1793-1802, 2019 | 83 | 2019 |
| Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor F Kinose, G Roscilli, S Lamartina, KD Anderson, F Bonelli, SG Spence, ... Mol Vis 11, 366-373, 2005 | 68 | 2005 |
| Optimization of fused bicyclic allosteric SHP2 inhibitors JT Bagdanoff, Z Chen, M Acker, YN Chen, H Chan, M Dore, B Firestone, ... Journal of medicinal chemistry 62 (4), 1781-1792, 2019 | 66 | 2019 |
| Teratogenic effects of the endothelin receptor antagonist L-753,037 in the rat S Spence, C Anderson, M Cukierski, D Patrick Reproductive Toxicology 13 (1), 15-29, 1999 | 63 | 1999 |
| Effects of the class III antiarrhythmic, dofetilide (UK‐68,798) on the heart rate of midgestation rat embryos, in vitro SG Spence, C Vetter, CM Hoe Teratology 49 (4), 282-292, 1994 | 52 | 1994 |
| Histone deacetylase inhibitors prolong cardiac repolarization through transcriptional mechanisms S Spence, M Deurinck, H Ju, M Traebert, LA McLean, J Marlowe, ... Toxicological Sciences 153 (1), 39-54, 2016 | 49 | 2016 |
| Developing blood vessels and associated extracellular matrix as substrates for neural crest migration in Japanese quail, Coturnix coturnix japonica. SG Spence, TJ Poole The International journal of developmental biology 38 (1), 85-98, 1994 | 44 | 1994 |
| Toxicokinetic analysis of losartan during gestation and lactation in the rat SG Spence, AG Zacchei, LL Lee, CL Baldwin, RA Berna, BA Mattson, ... Teratology 53 (4), 245-252, 1996 | 35 | 1996 |
| Evaluation of the reproductive and developmental toxicity of the AT1‐selective angiotensin II receptor antagonist Losartan in rats SG Spence, MA Cukierski, JM Manson, RT Robertson, RS Eydelloth Teratology 51 (6), 383-397, 1995 | 32 | 1995 |
| An alternative Alcian blue dye variant for the evaluation of fetal cartilage BG Redfern, L David Wise, S Spence Birth Defects Research Part B: Developmental and Reproductive Toxicology 80 …, 2007 | 27 | 2007 |
| Effects of VLA‐4 antagonists in rat whole embryo culture S Spence, C Vetter, WK Hagmann, G Van Riper, H Williams, RA Mumford, ... Teratology 65 (1), 26-37, 2002 | 22 | 2002 |
| Abstract ND09: The discovery and characterization of CFT8634: A potent and selective degrader of BRD9 for the treatment of SMARCB1-perturbed cancers KL Jackson, RV Agafonov, MW Carlson, P Chaturvedi, D Cocozziello, ... Cancer Research 82 (12_Supplement), ND09-ND09, 2022 | 20 | 2022 |
| Assessment of female and male fertility in Sprague–Dawley rats administered vorinostat, a histone deacetylase inhibitor LD Wise, S Spence, LP Saldutti, JS Kerr Birth Defects Research Part B: Developmental and Reproductive Toxicology 83 …, 2008 | 19 | 2008 |
| The Dutch‐Belted rabbit: An alternative breed for developmental toxicity testing S Spence Birth Defects Research Part B: Developmental and Reproductive Toxicology 68 …, 2003 | 19 | 2003 |
Jeremy K NicholsonAustralian National Phenome Center, Murdoch University + Imperial College LondonVerified email at murdoch.edu.au
