| Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes D Beck, JAI Thoms, D Perera, J Schütte, A Unnikrishnan, K Knezevic, ... Blood, The Journal of the American Society of Hematology 122 (14), e12-e22, 2013 | 153 | 2013 |
| Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells D Jing, VA Bhadri, D Beck, JAI Thoms, NA Yakob, JWH Wong, K Knezevic, ... Blood, The Journal of the American Society of Hematology 125 (2), 273-283, 2015 | 135 | 2015 |
| Integrative genomics identifies the molecular basis of resistance to azacitidine therapy in myelodysplastic syndromes A Unnikrishnan, E Papaemmanuil, D Beck, NP Deshpande, A Verma, ... Cell reports 20 (3), 572-585, 2017 | 118 | 2017 |
| ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer JAI Thoms, Y Birger, S Foster, K Knezevic, Y Kirschenbaum, ... Blood, The Journal of the American Society of Hematology 117 (26), 7079-7089, 2011 | 114 | 2011 |
| Targeting of a tropomyosin isoform to short microfilaments associated with the Golgi complex JM Percival, JAI Hughes, DL Brown, G Schevzov, K Heimann, B Vrhovski, ... Molecular biology of the cell 15 (1), 268-280, 2004 | 97 | 2004 |
| Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia E Diffner, D Beck, E Gudgin, JAI Thoms, K Knezevic, C Pridans, S Foster, ... Blood, The Journal of the American Society of Hematology 121 (12), 2289-2300, 2013 | 89 | 2013 |
| Functional mutations form at CTCF-cohesin binding sites in melanoma due to uneven nucleotide excision repair across the motif RC Poulos, JAI Thoms, YF Guan, A Unnikrishnan, JE Pimanda, ... Cell reports 17 (11), 2865-2872, 2016 | 79 | 2016 |
| Functional analysis of the actin-binding protein, tropomyosin 1, in neuroblastoma ML Yager, JAI Hughes, FJ Lovicu, PW Gunning, RP Weinberger, ... British journal of cancer 89 (5), 860-863, 2003 | 74 | 2003 |
| High‐molecular‐weight tropomyosins localize to the contractile rings of dividing CNS cells but are absent from malignant pediatric and adult CNS tumors JAI Hughes, CM Cooke‐Yarborough, NC Chadwick, G Schevzov, ... Glia 42 (1), 25-35, 2003 | 70 | 2003 |
| A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients SH Oram, JAI Thoms, C Pridans, ME Janes, SJ Kinston, S Anand, ... Oncogene 29 (43), 5796-5808, 2010 | 46 | 2010 |
| The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1 CL Carmichael, J Wang, T Nguyen, O Kolawole, A Benyoucef, ... Blood, The Journal of the American Society of Hematology 136 (8), 957-973, 2020 | 42 | 2020 |
| A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients D Beck, JAI Thoms, C Palu, T Herold, A Shah, J Olivier, L Boelen, ... Leukemia 32 (2), 263-272, 2018 | 38 | 2018 |
| Cytoskeletal responsiveness to progestins is dependent on progesterone receptor A levels EM McGowan, RP Weinberger, JD Graham, HD Hill, JAI Hughes, ... Journal of molecular endocrinology 31 (2), 241-254, 2003 | 37 | 2003 |
| Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells JAI Thoms, P Truong, S Subramanian, K Knezevic, G Harvey, Y Huang, ... Blood, The Journal of the American Society of Hematology 138 (16), 1441-1455, 2021 | 32 | 2021 |
| Systematic Screening of Promoter Regions Pinpoints Functional Cis-Regulatory Mutations in a Cutaneous Melanoma Genome RC Poulos, JAI Thoms, A Shah, D Beck, JE Pimanda, JWH Wong Molecular Cancer Research 13 (8), 1218-1226, 2015 | 30 | 2015 |
| Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias ML Tursky, D Beck, JAI Thoms, Y Huang, A Kumari, A Unnikrishnan, ... Leukemia 29 (4), 819-827, 2015 | 28 | 2015 |
| OncoCis: Annotation of cis-regulatory mutations in cancer D Perera, D Chacon, JAI Thoms, RC Poulos, A Shilen, D Beck, ... Genome Biology 15, 485, 2014 | 27 | 2014 |
| MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation Y Huang, JAI Thoms, ML Tursky, K Knezevic, D Beck, V Chandrakanthan, ... Leukemia 30 (7), 1552-1561, 2016 | 26 | 2016 |
| Demethylation and up-regulation of an oncogene after hypomethylating therapy YC Liu, J Kwon, E Fabiani, Z Xiao, YV Liu, MY Follo, J Liu, H Huang, ... New England Journal of Medicine 386 (21), 1998-2010, 2022 | 25 | 2022 |
| A tropomyosin 1 induced defect in cytokinesis can be rescued by elevated expression of cofilin JAI Thoms, HM Loch, JR Bamburg, PW Gunning, RP Weinberger Cell Motility and the Cytoskeleton 65 (12), 979-990, 2008 | 25 | 2008 |
john pimandaUNSW SYDNEYVerified email at unsw.edu.au
