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William Lees
William Lees
Birkbeck, University of London
Verified email at lees.org.uk
Title
Cited by
Cited by
Year
Inferred allelic variants of immunoglobulin receptor genes: a system for their evaluation, documentation, and naming
M Ohlin, C Scheepers, M Corcoran, WD Lees, CE Busse, D Bagnara, ...
Frontiers in immunology 10, 441872, 2019
582019
A computational analysis of the antigenic properties of haemagglutinin in influenza A H3N2
WD Lees, DS Moss, AJ Shepherd
Bioinformatics 26 (11), 1403-1408, 2010
562010
Diversity in immunogenomics: the value and the challenge
K Peng, Y Safonova, M Shugay, AB Popejoy, OL Rodriguez, F Breden, ...
Nature methods 18 (6), 588-591, 2021
482021
Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences
E Smakaj, L Babrak, M Ohlin, M Shugay, B Briney, D Tosoni, C Galli, ...
Bioinformatics 36 (6), 1731-1739, 2020
452020
OGRDB: a reference database of inferred immune receptor genes
W Lees, CE Busse, M Corcoran, M Ohlin, C Scheepers, FA Matsen IV, ...
Nucleic acids research 48 (D1), D964-D970, 2020
382020
Germline immunoglobulin genes: disease susceptibility genes hidden in plain sight?
AM Collins, G Yaari, AJ Shepherd, W Lees, CT Watson
Current Opinion in Systems Biology 24, 100-108, 2020
342020
VDJbase: an adaptive immune receptor genotype and haplotype database
A Omer, O Shemesh, A Peres, P Polak, AJ Shepherd, CT Watson, ...
Nucleic acids research 48 (D1), D1051-D1056, 2020
322020
T cell receptor beta germline variability is revealed by inference from repertoire data
A Omer, A Peres, OL Rodriguez, CT Watson, W Lees, P Polak, AM Collins, ...
Genome medicine 14, 1-19, 2022
272022
sumrep: A Summary Statistic Framework for Immune Receptor Repertoire Comparison and Model Validation
BJ Olson, P Moghimi, CA Schramm, A Obraztsova, D Ralph, ...
Frontiers in immunology 10, 2533, 2019
272019
Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein
L Stejskal, WD Lees, DS Moss, M Palor, RJ Bingham, AJ Shepherd, ...
PLOS Computational Biology 16 (2), e1007710, 2020
222020
Commentary on Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: relevance in infectious diseases and vaccination studies in human populations
AM Collins, A Peres, MM Corcoran, CT Watson, G Yaari, WD Lees, ...
Genes & Immunity 22 (7), 335-338, 2021
202021
Evaluation of a novel multi-immunogen vaccine strategy for targeting 4E10/10E8 neutralizing epitopes on HIV-1 gp41 membrane proximal external region
S Banerjee, H Shi, M Banasik, H Moon, W Lees, Y Qin, A Harley, ...
Virology 505, 113-126, 2017
192017
Utilities for high-throughput analysis of B-cell clonal lineages
WD Lees, AJ Shepherd
Journal of immunology research 2015, 2015
172015
investigating substitutions in antibody–antigen complexes Using Molecular Dynamics: a case study with Broad-spectrum, influenza a antibodies
WD Lees, L Stejskal, DS Moss, AJ Shepherd
Frontiers in Immunology 8, 244887, 2017
152017
N-Linked glycans on influenza A H3N2 hemagglutinin constrain binding of host antibodies, but shielding is limited
K Pentiah, WD Lees, DS Moss, AJ Shepherd
Glycobiology 25 (1), 124-132, 2015
142015
Analysis of antigenically important residues in human influenza A virus in terms of B-cell epitopes
WD Lees, DS Moss, AJ Shepherd
Journal of virology 85 (17), 8548-8555, 2011
142011
An entropic safety catch controls hepatitis C virus entry and antibody resistance
L Stejskal, MD Kalemera, CB Lewis, M Palor, L Walker, T Daviter, ...
Elife 11, e71854, 2022
102022
A BALB/c IGHV reference set, defined by haplotype analysis of long-read VDJ-c sequences from F1 (BALB/cx C57BL/6) mice
KJL Jackson, JT Kos, W Lees, WS Gibson, ML Smith, A Peres, G Yaari, ...
Frontiers in Immunology 13, 888555, 2022
102022
Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop …
R Pan, Y Qin, M Banasik, W Lees, AJ Shepherd, MW Cho, XP Kong
Journal of virology 92 (7), 10.1128/jvi. 01894-17, 2018
102018
Studying antibody repertoires with next-generation sequencing
WD Lees, AJ Shepherd
Bioinformatics: Volume II: Structure, Function, and Applications, 257-270, 2017
92017
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Articles 1–20