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Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease JC Crosby, GM Peloso, PL Auer, et al. New England Journal of Medicine 371, 22-31, 2014 | 685 | 2014 |
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction R Do, NO Stitziel, HH Won, AB Jørgensen, S Duga, P Angelica Merlini, ... Nature 518 (7537), 102-106, 2015 | 643 | 2015 |
Polygenic risk scores for prediction of breast cancer and breast cancer subtypes N Mavaddat, K Michailidou, J Dennis, M Lush, L Fachal, A Lee, JP Tyrer, ... The American Journal of Human Genetics 104 (1), 21-34, 2019 | 521 | 2019 |
Rare and low-frequency coding variants alter human adult height E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ... Nature 542 (7640), 186-190, 2017 | 496 | 2017 |
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ... Nature 590 (7845), 290-299, 2021 | 494 | 2021 |
Statistical design and analysis of RNA sequencing data PL Auer, RW Doerge Genetics 185 (2), 405-416, 2010 | 467 | 2010 |
Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease NO Stitziel, HH Won, AC Morrison, GM Peloso, R Do, LA Lange, ... The New England Journal of Medicine 371, 2072-2082, 2014 | 403* | 2014 |
Exome-wide association study of plasma lipids in> 300,000 individuals DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ... Nature genetics 49 (12), 1758-1766, 2017 | 399 | 2017 |
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture HF Zheng, V Forgetta, YH Hsu, K Estrada, A Rosello‐Diez, PJ Leo, ... Nature 526 (7571), 112-117, 2015 | 383 | 2015 |
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators New England Journal of Medicine 374 (12), 1134-1144, 2016 | 338 | 2016 |
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks GM Peloso, PL Auer, JC Bis, A Voorman, AC Morrison, NO Stitziel, ... The American Journal of Human Genetics 94 (2), 223-232, 2014 | 337 | 2014 |
Breast cancer risk from modifiable and nonmodifiable risk factors among white women in the United States P Maas, M Barrdahl, AD Joshi, PL Auer, MM Gaudet, RL Milne, ... JAMA oncology 2 (10), 1295-1302, 2016 | 291 | 2016 |
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ... Nature genetics 49 (12), 1767-1778, 2017 | 249 | 2017 |
The fate of duplicated genes in a polyploid plant genome A Roulin, PL Auer, M Libault, J Schlueter, A Farmer, G May, G Stacey, ... The Plant Journal 73 (1), 143-153, 2013 | 249 | 2013 |
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity V Turcot, Y Lu, HM Highland, C Schurmann, AE Justice, RS Fine, ... Nature genetics 50 (1), 26-41, 2018 | 232 | 2018 |
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol LA Lange, Y Hu, H Zhang, C Xue, EM Schmidt, ZZ Tang, C Bizon, ... The American Journal of Human Genetics 94 (2), 233-245, 2014 | 213 | 2014 |
Rare variant association studies: considerations, challenges and opportunities PL Auer, G Lettre Genome medicine 7 (1), 1-11, 2015 | 209 | 2015 |
Meta-analysis of gene-level tests for rare variant association DJ Liu, GM Peloso, X Zhan, OL Holmen, M Zawistowski, S Feng, ... Nature genetics 46 (2), 200-204, 2014 | 203 | 2014 |
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci C Liu, AT Kraja, JA Smith, JA Brody, N Franceschini, JC Bis, K Rice, ... Nature genetics 48 (10), 1162-1170, 2016 | 196 | 2016 |