| Coexistence of passive and carrier-mediated processes in drug transport K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ... Nature reviews Drug discovery 9 (8), 597-614, 2010 | 507 | 2010 |
| Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure–activity relationship M Murias, N Handler, T Erker, K Pleban, G Ecker, P Saiko, T Szekeres, ... Bioorganic & medicinal chemistry 12 (21), 5571-5578, 2004 | 355 | 2004 |
| On the relationship between feature selection and classification accuracy A Janecek, W Gansterer, M Demel, G Ecker New challenges for feature selection in data mining and knowledge discovery …, 2008 | 340 | 2008 |
| Open PHACTS: semantic interoperability for drug discovery AJ Williams, L Harland, P Groth, S Pettifer, C Chichester, EL Willighagen, ... Drug discovery today 17 (21-22), 1188-1198, 2012 | 315 | 2012 |
| Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of toxicology 91 (11), 3477-3505, 2017 | 187 | 2017 |
| The importance of a nitrogen atom in modulators of multidrug resistance G Ecker, M Huber, D Schmid, P Chiba Molecular pharmacology 56 (4), 791-796, 1999 | 184 | 1999 |
| Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands L Richter, C De Graaf, W Sieghart, Z Varagic, M Mörzinger, IJP De Esch, ... Nature chemical biology 8 (5), 455, 2012 | 180 | 2012 |
| P-glycoprotein substrate binding domains are located at the transmembrane domain/transmembrane domain interfaces: a combined photoaffinity labeling-protein homology modeling … K Pleban, S Kopp, E Csaszar, M Peer, T Hrebicek, A Rizzi, GF Ecker, ... Molecular pharmacology 67 (2), 365-374, 2005 | 165 | 2005 |
| Prediction of drug–ABC-transporter interaction—Recent advances and future challenges F Montanari, GF Ecker Advanced drug delivery reviews 86, 17-26, 2015 | 141 | 2015 |
| Structural requirements for activity of propafenone-type modulators in P-glycoprotein-mediated multidrug resistance. P Chiba, G Ecker, D Schmid, J Drach, B Tell, S Goldenberg, V Gekeler Molecular Pharmacology 49 (6), 1122-1130, 1996 | 133 | 1996 |
| The N terminus of monoamine transporters is a lever required for the action of amphetamines S Sucic, S Dallinger, B Zdrazil, R Weissensteiner, TN Jørgensen, M Holy, ... Journal of Biological Chemistry 285 (14), 10924-10938, 2010 | 132 | 2010 |
| Reversal of antifungal resistance mediated by ABC efflux pumps from Candida albicans functionally expressed in yeast M Schuetzer-Muehlbauer, B Willinger, R Egner, G Ecker, K Kuchler International journal of antimicrobial agents 22 (3), 291-300, 2003 | 125 | 2003 |
| Evidence-based approach to assess passive diffusion and carrier-mediated drug transport L Di, P Artursson, A Avdeef, GF Ecker, B Faller, H Fischer, JB Houston, ... Drug discovery today 17 (15-16), 905-912, 2012 | 108 | 2012 |
| Kinetics for Drug Discovery: an industry-driven effort to target drug residence time DA Schuetz, WEA de Witte, YC Wong, B Knasmueller, L Richter, DB Kokh, ... Drug Discovery Today 22 (6), 896-911, 2017 | 105 | 2017 |
| Substituted 4-acylpyrazoles and 4-acylpyrazolones: synthesis and multidrug resistance-modulating activity P Chiba, W Holzer, M Landau, G Bechmann, K Lorenz, B Plagens, ... Journal of medicinal chemistry 41 (21), 4001-4011, 1998 | 103 | 1998 |
| Synthesis and in vitro multidrug resistance modulating activity of a series of dihydrobenzopyrans and tetrahydroquinolines R Hiessböck, C Wolf, E Richter, M Hitzler, P Chiba, M Kratzel, G Ecker Journal of medicinal chemistry 42 (11), 1921-1926, 1999 | 95 | 1999 |
| Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition D Smith, P Artursson, A Avdeef, L Di, GF Ecker, B Faller, JB Houston, ... Molecular pharmaceutics 11 (6), 1727-1738, 2014 | 94 | 2014 |
| Structure–activity relationship studies of propafenone analogs based on P-glycoprotein ATPase activity measurements D Schmid, G Ecker, S Kopp, M Hitzler, P Chiba Biochemical pharmacology 58 (9), 1447-1456, 1999 | 93 | 1999 |
| Structure–activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein I Jabeen, K Pleban, U Rinner, P Chiba, GF Ecker Journal of medicinal chemistry 55 (7), 3261-3273, 2012 | 92 | 2012 |
| A novel flow based hollow-fiber blood–brain barrier in vitro model with immortalised cell line PBMEC/C1–2 W Neuhaus, R Lauer, S Oelzant, UP Fringeli, GF Ecker, CR Noe Journal of biotechnology 125 (1), 127-141, 2006 | 88 | 2006 |
Barbara ZdrazilPrincipal Investigator at University of ViennaVerified email at univie.ac.at
