Targeting adenosine receptor signaling in cancer immunotherapy K Sek, C Mølck, GD Stewart, L Kats, PK Darcy, PA Beavis International journal of molecular sciences 19 (12), 3837, 2018 | 186 | 2018 |
Differential GLP-1R binding and activation by peptide and non-peptide agonists X Zhang, MJ Belousoff, P Zhao, AJ Kooistra, TT Truong, SY Ang, ... Molecular Cell 80 (3), 485-500. e7, 2020 | 120 | 2020 |
CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy L Giuffrida, K Sek, MA Henderson, J Lai, AXY Chen, D Meyran, KL Todd, ... Nature communications 12 (1), 3236, 2021 | 118 | 2021 |
A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain PD Ramírez-García, JS Retamal, P Shenoy, W Imlach, M Sykes, N Truong, ... Nature Nanotechnology 14 (12), 1150-1159, 2019 | 115 | 2019 |
Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity GD Stewart, C Valant, SJ Dowell, D Mijaljica, RJ Devenish, PJ Scammells, ... Journal of Pharmacology and Experimental Therapeutics 331 (1), 277-286, 2009 | 64 | 2009 |
Murine GPRC6A mediates cellular responses to L-amino acids, but not osteocalcin variants P Rueda, E Harley, Y Lu, GD Stewart, S Fabb, N Diepenhorst, B Cremers, ... PloS one 11 (1), e0146846, 2016 | 49 | 2016 |
Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery K Sengmany, J Singh, GD Stewart, PJ Conn, A Christopoulos, KJ Gregory Neuropharmacology 115, 60-72, 2017 | 47 | 2017 |
Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics DL Spark, A Fornito, CJ Langmead, GD Stewart Translational Psychiatry 12 (1), 147, 2022 | 34 | 2022 |
Detection of Novel Functional Selectivity at M3 Muscarinic Acetylcholine Receptors Using a Saccharomyces cerevisiae Platform GD Stewart, PM Sexton, A Christopoulos ACS chemical biology 5 (4), 365-375, 2010 | 32 | 2010 |
The A2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation and ROS production in colorectal cancer cells via adenosine receptor-independent mechanism C Mølck, J Ryall, LM Failla, JL Coates, JM Pascussi, JK Heath, G Stewart, ... Cancer Letters 383 (1), 135-143, 2016 | 29 | 2016 |
Pharmacology of 5HT2C receptor-mediated ERK1/2 phosphorylation: agonist-specific activation pathways and the impact of RNA editing TD Werry, GD Stewart, MF Crouch, A Watts, PM Sexton, A Christopoulos Biochemical pharmacology 76 (10), 1276-1287, 2008 | 26 | 2008 |
Prediction of functionally selective allosteric interactions at an M3 muscarinic acetylcholine receptor mutant using Saccharomyces cerevisiae GD Stewart, PM Sexton, A Christopoulos Molecular pharmacology 78 (2), 205-214, 2010 | 24 | 2010 |
Allosteric interactions between GABAB1 subunits control orthosteric binding sites occupancy within GABAB oligomers GD Stewart, L Comps-Agrar, LB Nørskov-Lauritsen, JP Pin, J Kniazeff Neuropharmacology 136, 92-101, 2018 | 18 | 2018 |
SUMMARY OF PRODUCT CHARACTERISTICS.^« C Oral, GB Park | 9 | 2010 |
Targeting appetite and satiety in diabetes and obesity, via G protein-coupled receptors NBC Piper, EA Whitfield, GD Stewart, X Xu, SGB Furness Biochemical Pharmacology 202, 115115, 2022 | 7 | 2022 |
Translation-focused approaches to GPCR drug discovery for cognitive impairments associated with schizophrenia CJ Hatzipantelis, M Langiu, TH Vandekolk, TL Pierce, J Nithianantharajah, ... ACS Pharmacology & Translational Science 3 (6), 1042-1062, 2020 | 7 | 2020 |
β-Arrestin-2-dependent mechanism of GPR52 signaling in frontal cortical neurons CJ Hatzipantelis, Y Lu, DL Spark, CJ Langmead, GD Stewart ACS Chemical Neuroscience 11 (14), 2077-2084, 2020 | 7 | 2020 |
In the loop: Extrastriatal regulation of spiny projection neurons by GPR52 DL Spark, M Mao, S Ma, M Sarwar, CJ Nowell, DM Shackleford, ... ACS Chemical Neuroscience 11 (14), 2066-2076, 2020 | 6 | 2020 |
Metabotropic Receptors for Glutamate and GABA G Stewart, J Kniazeff, L Prézeau, P Rondard, JP Pin, C Goudet Pharmacology, 2012 | 3 | 2012 |
Development of gas micro-strip chambers for high rate radiation detection and tracking R Bouclier, A Pansky, M Heidrich, GK Oakham, A Trombini, JA Armitage, ... | 3 | 1992 |