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Chuang Guo
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COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas
X Ren, W Wen, X Fan, W Hou, B Su, P Cai, J Li, Y Liu, F Tang, F Zhang, ...
Cell 184 (7), 1895-1913. e19, 2021
6112021
Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm
C Guo, B Li, H Ma, X Wang, P Cai, Q Yu, L Zhu, L Jin, C Jiang, J Fang, ...
Nature communications 11 (1), 3924, 2020
1892020
Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution
B Li, W Zhang, C Guo, H Xu, L Li, M Fang, Y Hu, X Zhang, X Yao, M Tang, ...
Nature methods 19 (6), 662-670, 2022
1662022
IGF-1 promotes the development and cytotoxic activity of human NK cells
F Ni, R Sun, B Fu, F Wang, C Guo, Z Tian, H Wei
Nature communications 4 (1), 1479, 2013
982013
Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss
C Guo, P Cai, L Jin, Q Sha, Q Yu, W Zhang, C Jiang, Q Liu, D Zong, K Li, ...
Cell Discovery 7 (1), 1-15, 2021
952021
MicroRNA-362-5p promotes tumor growth and metastasis by targeting CYLD in hepatocellular carcinoma
F Ni, H Zhao, H Cui, Z Wu, L Chen, Z Hu, C Guo, Y Liu, Z Chen, X Wang, ...
Cancer letters 356 (2), 809-818, 2015
802015
Tocilizumab treatment in severe COVID-19 patients attenuates the inflammatory storm incited by monocyte centric immune interactions revealed by single-cell analysis
C Guo, B Li, H Ma, X Wang, P Cai, Q Yu, L Zhu, L Jin, C Jiang, J Fang, ...
BioRxiv, 2020.04. 08.029769, 2020
612020
MicroRNA transcriptomes of distinct human NK cell populations identify miR-362-5p as an essential regulator of NK cell function
F Ni, C Guo, R Sun, B Fu, Y Yang, L Wu, S Ren, Z Tian, H Wei
Scientific Reports 5 (1), 9993, 2015
562015
Restoration of HBV-specific CD8+ T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-α therapy
D Wang, B Fu, X Shen, C Guo, Y Liu, J Zhang, R Sun, Y Ye, J Li, Z Tian, ...
Signal Transduction and Targeted Therapy 6 (1), 376, 2021
442021
Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes
N Liu, C Jiang, P Cai, Z Shen, W Sun, H Xu, M Fang, X Yao, L Zhu, X Gao, ...
Cell Reports 37 (1), 2021
372021
Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis
Q Liu, LC Zaba, AT Satpathy, M Longmire, W Zhang, K Li, J Granja, C Guo, ...
Nature communications 11 (1), 5843, 2020
292020
Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19
C Guo, M Wu, B Huang, R Zhao, L Jin, B Fu, P Wang, D Wang, M Zheng, ...
Genome medicine 14 (1), 46, 2022
212022
NKp30+ NK cells are associated with HBV control during pegylated-interferon-alpha-2b therapy of chronic hepatitis B
X Shen, B Fu, Y Liu, C Guo, Y Ye, R Sun, J Li, Z Tian, H Wei
Scientific reports 6 (1), 38778, 2016
202016
Immunomodulation induced during interferon-α therapy impairs the anti-HBV immune response through CD24+ CD38hi B cells
B Fu, D Wang, X Shen, C Guo, Y Liu, Y Ye, R Sun, J Li, Z Tian, H Wei
Frontiers in Immunology 11, 591269, 2020
162020
Single-cell transcriptome profiling and chromatin accessibility reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus
C Guo, Q Liu, D Zong, W Zhang, Z Zuo, Q Yu, Q Sha, L Zhu, X Gao, ...
Cell Reports 41 (6), 2022
142022
Single-cell heterogeneity of the liver-infiltrating lymphocytes in individuals with chronic Echinococcus multilocularis infection
T Jiang, W Sun, T Aji, Y Shao, C Guo, C Zhang, B Ran, J Hou, A Yasen, ...
Infection and immunity 90 (11), e00177-22, 2022
82022
CD3brightCD56+ T cells associate with pegylated interferon-alpha treatment nonresponse in chronic hepatitis B patients
C Guo, X Shen, B Fu, Y Liu, Y Chen, F Ni, Y Ye, R Sun, J Li, Z Tian, H Wei
Scientific reports 6 (1), 25567, 2016
82016
Kir3Ds1/hla-B Bw4-80ile genotype is correlated with the iFn-α Therapy response in hepatitis B e antigen-Positive chronic hepatitis B
W Li, X Shen, B Fu, C Guo, Y Liu, Y Ye, R Sun, J Li, Z Tian, H Wei
Frontiers in Immunology 8, 1285, 2017
72017
Chromatin accessibility landscapes of immune cells in rheumatoid arthritis nominate monocytes in disease pathogenesis
D Zong, B Huang, Y Li, Y Lu, N Xiang, C Guo, Q Liu, Q Sha, P Du, Q Yu, ...
BMC biology 19, 1-15, 2021
52021
Single-cell analysis of severe COVID-19 patients reveals a monocyte-driven inflammatory storm attenuated by Tocilizumab
C Guo, B Li, H Ma, X Wang, P Cai, Q Yu, L Zhu, L Jin, C Jiang, J Fang, ...
42020
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