Ludwig Dubois
Ludwig Dubois
Verified email at maastrichtuniversity.nl
Title
Cited by
Cited by
Year
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
KMA Rouschop, T Van Den Beucken, L Dubois, H Niessen, J Bussink, ...
The Journal of clinical investigation 120 (1), 127-141, 2010
6302010
Disparity between in vivo EGFR expression and 89Zr-labeled cetuximab uptake assessed with PET
HJWL Aerts, L Dubois, L Perk, P Vermaelen, GAMS van Dongen, ...
Journal of Nuclear Medicine 50 (1), 123-131, 2009
1972009
Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model
L Dubois, NG Lieuwes, A Maresca, A Thiry, CT Supuran, A Scozzafava, ...
Radiotherapy and Oncology 92 (3), 423-428, 2009
1762009
Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies
P Ebbesen, EO Pettersen, TA Gorr, G Jobst, K Williams, J Kieninger, ...
Journal of enzyme inhibition and medicinal chemistry 24 (sup1), 1-39, 2009
1672009
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation
L Dubois, S Peeters, NG Lieuwes, N Geusens, A Thiry, S Wigfield, F Carta, ...
Radiotherapy and Oncology 99 (3), 424-431, 2011
1632011
Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors
L Dubois, K Douma, CT Supuran, RK Chiu, MAMJ van Zandvoort, ...
Radiotherapy and oncology 83 (3), 367-373, 2007
1522007
How do changes in the mtDNA and mitochondrial dysfunction influence cancer and cancer therapy? Challenges, opportunities and models
MW Van Gisbergen, AM Voets, MHW Starmans, IFM De Coo, R Yadak, ...
Mutation Research/Reviews in Mutation Research 764, 16-30, 2015
1292015
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
KM Rouschop, LJ Dubois, TG Keulers, T van den Beucken, P Lambin, ...
Proceedings of the National Academy of Sciences 110 (12), 4622-4627, 2013
1292013
Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo
J Theys, O Pennington, L Dubois, G Anlezark, T Vaughan, A Mengesha, ...
British journal of cancer 95 (9), 1212-1219, 2006
1232006
Evaluation of hypoxia in an experimental rat tumour model by [18 F] fluoromisonidazole PET and immunohistochemistry
L Dubois, W Landuyt, K Haustermans, P Dupont, G Bormans, ...
British journal of cancer 91 (11), 1947-1954, 2004
1172004
A comparative study of the hypoxia PET tracers [18F] HX4,[18F] FAZA, and [18F] FMISO in a preclinical tumor model
SGJA Peeters, CML Zegers, NG Lieuwes, W van Elmpt, J Eriksson, ...
International Journal of Radiation Oncology* Biology* Physics 91 (2), 351-359, 2015
1122015
Preclinical evaluation and validation of [18F] HX4, a promising hypoxia marker for PET imaging
LJ Dubois, NG Lieuwes, MHM Janssen, WJM Peeters, AD Windhorst, ...
Proceedings of the National Academy of Sciences 108 (35), 14620-14625, 2011
1102011
PET imaging of hypoxia using [18F]HX4: a phase I trial
J van Loon, MHM Janssen, M Íllers, HJWL Aerts, L Dubois, ...
European journal of nuclear medicine and molecular imaging 37 (9), 1663-1668, 2010
1072010
Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia
V Akurathi, L Dubois, NG Lieuwes, SK Chitneni, BJ Cleynhens, D Vullo, ...
Nuclear medicine and biology 37 (5), 557-564, 2010
932010
Decision support systems for personalized and participative radiation oncology
P Lambin, J Zindler, BGL Vanneste, L Van De Voorde, D Eekers, ...
Advanced drug delivery reviews 109, 131-153, 2017
782017
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
EO Pettersen, P Ebbesen, RG Gieling, KJ Williams, L Dubois, P Lambin, ...
Journal of enzyme inhibition and medicinal chemistry 30 (5), 689-721, 2015
752015
TH-302 in combination with radiotherapy enhances the therapeutic outcome and is associated with pretreatment [18F] HX4 hypoxia PET imaging
SGJA Peeters, CML Zegers, R Biemans, NG Lieuwes, ...
Clinical Cancer Research 21 (13), 2984-2992, 2015
722015
Is there a causal relationship between genetic changes and radiomics-based image features? An in vivo preclinical experiment with doxycycline inducible GADD34 tumor cells
KM Panth, RTH Leijenaar, S Carvalho, NG Lieuwes, A Yaromina, ...
Radiotherapy and Oncology 116 (3), 462-466, 2015
692015
Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: a new concept of dual targeting drugs
L Dubois, SGJA Peeters, SJA van Kuijk, A Yaromina, NG Lieuwes, ...
Radiotherapy and Oncology 108 (3), 523-528, 2013
682013
Radiotherapy combined with the immunocytokine L19-IL2 provides long-lasting antitumor effects
CML Zegers, NH Rekers, DHF Quaden, NG Lieuwes, A Yaromina, ...
Clinical Cancer Research 21 (5), 1151-1160, 2015
642015
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