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Joshua A. Mitchell
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Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS
WH Zhang, MK Herde, JA Mitchell, JH Whitfield, AB Wulff, V Vongsouthi, ...
Nature chemical biology 14 (9), 861-869, 2018
612018
T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein
CR Fisher, HJ Sutton, JA Kaczmarski, HA McNamara, B Clifton, J Mitchell, ...
PLoS pathogens 13 (7), e1006469, 2017
472017
Structural and evolutionary approaches to the design and optimization of fluorescence-based small molecule biosensors
JA Kaczmarski, JA Mitchell, MA Spence, V Vongsouthi, CJ Jackson
Current Opinion in Structural Biology 57, 31-38, 2019
312019
Trends in U.S. Ambulatory Cardiovascular Care 2013 to 2017: JACC Review Topic of the Week
TM Maddox, Y Song, J Allen, PS Chan, A Khan, JJ Lee, J Mitchell, ...
Journal of the American College of Cardiology 75 (1), 93-112, 2020
292020
Rangefinder: A semisynthetic FRET sensor design algorithm
JA Mitchell, JH Whitfield, WH Zhang, C Henneberger, H Janovjak, ...
Acs Sensors 1 (11), 1286-1290, 2016
112016
Open Force Field BespokeFit: Automating Bespoke Torsion Parametrization At Scale
JT Horton, S Boothroyd, J Wagner, JA Mitchell, T Gokey, DL Dotson, ...
Journal of Chemical Information and Modeling 62 (22), 5622-5633, 2022
102022
A Rationally and Computationally Designed Fluorescent Biosensor for d-Serine
V Vongsouthi, JH Whitfield, P Unichenko, JA Mitchell, B Breithausen, ...
ACS sensors 6 (11), 4193-4205, 2021
72021
Computational design and experimental characterisation of a stable human heparanase variant
C Whitefield, N Hong, JA Mitchell, CJ Jackson
RSC Chemical Biology 3 (3), 341-349, 2022
52022
A computationally designed fluorescent biosensor for D-serine
V Vongsouthi, JH Whitfield, P Unichenko, JA Mitchell, B Breithausen, ...
bioRxiv, 2020.08. 18.255380, 2020
42020
Method for developing optical sensors using a synthetic dye-fluorescent protein FRET pair and computational modeling and assessment
JA Mitchell, WH Zhang, MK Herde, C Henneberger, H Janovjak, ...
Synthetic Protein Switches: Methods and Protocols, 89-99, 2017
32017
Development and benchmarking of an open, self-consistent force field for proteins and small molecules from the open force field initiative
CE Cavender, PK Behara, S Boothroyd, DL Dotson, JT Horton, JA Mitchell, ...
Biophysical Journal 122 (3), 421a, 2023
12023
Capturing the Dynamics of a Spring-Loaded Protein
JA Mitchell, ML O’Mara
Structure 25 (7), 963-964, 2017
12017
OpenMM 8: Molecular Dynamics Simulation with Machine Learning Potentials
P Eastman, R Galvelis, RP PelŠez, CRA Abreu, SE Farr, E Gallicchio, ...
arXiv preprint arXiv:2310.03121, 2023
2023
Early Increases in Blood Pressure and Major Adverse Cardiovascular Events in Patients With Renal Cell Carcinoma and Thyroid Cancer Treated With VEGFR TKIs
V Narayan, T Liu, Y Song, J Mitchell, JR Sicks, I Gareen, L Sun, ...
Journal of the National Comprehensive Cancer Network 21 (10), 1039-1049. e10, 2023
2023
HYPERTENSION, CARDIOVASCULAR EVENTS AND SURVIVAL IN RENAL CELL CARCINOMA AND THYROID CANCER PATIENTS TREATED WITH VEGFR TYROSINE KINASE INHIBITORS
V Narayan, T Liu, Y Song, J Mitchell, J Sicks, IF Gareen, L Sun, ...
Journal of the American College of Cardiology 81 (8_Supplement), 2378-2378, 2023
2023
Molecular Dynamics for Synthetic Biology
JA Mitchell
PQDT-Global, 2022
2022
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