Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2626* | 2018 |
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses A Okbay, BML Baselmans, JE De Neve, P Turley, MG Nivard, MA Fontana, ... Nature genetics 48 (6), 624-633, 2016 | 1046 | 2016 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1044 | 2019 |
Meta-analysis of genome-wide association studies of anxiety disorders T Otowa, K Hek, M Lee, EM Byrne, SS Mirza, MG Nivard, T Bigdeli, ... Molecular psychiatry 21 (10), 1391-1399, 2016 | 509 | 2016 |
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits AE Justice, TW Winkler, MF Feitosa, M Graff, VA Fisher, K Young, L Barata, ... Nature communications 8 (1), 14977, 2017 | 215 | 2017 |
Major depressive disorder working group of the psychiatric genomics consortium DM Howard, MJ Adams, WD Hill, TK Clarke, MJ Adams, TK Clarke, ... Nat. Commun 11, 230, 2020 | 185 | 2020 |
Psychiatric epidemiology in Turkey: main advances in recent studies and future directions. T Binbay, N Direk, T Aker, Y Akvardar, K Alptekin, C Cimilli, B Cam, ... Turk Psikiyatri Dergisi 25 (4), 2014 | 163* | 2014 |
Anxiety disorders and salivary cortisol levels in older adults: a population-based study K Hek, N Direk, RS Newson, A Hofman, WJG Hoogendijk, CL Mulder, ... Psychoneuroendocrinology 38 (2), 300-305, 2013 | 150 | 2013 |
Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin JL Bolton, C Hayward, N Direk, JG Lewis, GL Hammond, LA Hill, ... PLoS genetics 10 (7), e1004474, 2014 | 146 | 2014 |
The genetics of the mood disorder spectrum: genome-wide association analyses of more than 185,000 cases and 439,000 controls JRI Coleman, HA Gaspar, J Bryois, EM Byrne, AJ Forstner, PA Holmans, ... Biological psychiatry 88 (2), 169-184, 2020 | 145 | 2020 |
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors N Mullins, JE Kang, AI Campos, JRI Coleman, AC Edwards, H Galfalvy, ... Biological psychiatry 91 (3), 313-327, 2022 | 140 | 2022 |
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ... Biological psychiatry 90 (9), 611-620, 2021 | 134 | 2021 |
Thyroid function within the normal range and the risk of depression: a population-based cohort study M Medici, N Direk, WE Visser, TIM Korevaar, A Hofman, TJ Visser, ... The Journal of Clinical Endocrinology & Metabolism 99 (4), 1213-1219, 2014 | 122 | 2014 |
24‐hour activity rhythm and sleep disturbances in depression and anxiety: A population‐based study of middle‐aged and older persons AI Luik, LA Zuurbier, N Direk, A Hofman, EJW Van Someren, H Tiemeier Depression and anxiety 32 (9), 684-692, 2015 | 120 | 2015 |
Does childhood trauma moderate polygenic risk for depression? A meta-analysis of 5765 subjects from the psychiatric genomics consortium WJ Peyrot, S Van der Auwera, Y Milaneschi, CV Dolan, PAF Madden, ... Biological psychiatry 84 (2), 138-147, 2018 | 118 | 2018 |
The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study O Giannakopoulou, K Lin, X Meng, MH Su, PH Kuo, RE Peterson, ... JAMA psychiatry 78 (11), 1258-1269, 2021 | 105 | 2021 |
Sexual activity and physical tenderness in older adults: cross-sectional prevalence and associated characteristics R Freak-Poli, M Kirkman, G De Castro Lima, N Direk, OH Franco, ... The journal of sexual medicine 14 (7), 918-927, 2017 | 100 | 2017 |
Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel … AT Amare, A Vaez, YH Hsu, N Direk, Z Kamali, DM Howard, AM McIntosh, ... Molecular psychiatry 25 (7), 1420-1429, 2020 | 92 | 2020 |
An analysis of two genome-wide association meta-analyses identifies a new locus for broad depression phenotype N Direk, S Williams, JA Smith, S Ripke, T Air, AT Amare, N Amin, ... Biological psychiatry 82 (5), 322-329, 2017 | 91 | 2017 |
Sex-dependent shared and nonshared genetic architecture across mood and psychotic disorders GAM Blokland, J Grove, CY Chen, C Cotsapas, S Tobet, R Handa, ... Biological psychiatry 91 (1), 102-117, 2022 | 78 | 2022 |