Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 3826 | 2016 |
Pan-cancer analysis of whole genomes I The, TPCA of Whole, Genomes Consortium Nature 578 (7793), 82, 2020 | 1506 | 2020 |
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma M Krauthammer, Y Kong, BH Ha, P Evans, A Bacchiocchi, JP McCusker, ... Nature genetics 44 (9), 1006-1014, 2012 | 1322 | 2012 |
Whole-genome landscapes of major melanoma subtypes NK Hayward, JS Wilmott, N Waddell, PA Johansson, MA Field, K Nones, ... Nature 545 (7653), 175-180, 2017 | 1260 | 2017 |
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma S Yokoyama, SL Woods, GM Boyle, LG Aoude, S MacGregor, V Zismann, ... Nature 480 (7375), 99-103, 2011 | 553 | 2011 |
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing MS Stark, SL Woods, MG Gartside, VF Bonazzi, K Dutton-Regester, ... Nature genetics 44 (2), 165-169, 2012 | 218 | 2012 |
Melanoma cell invasiveness is regulated by miR‐211 suppression of the BRN2 transcription factor GM Boyle, SL Woods, VF Bonazzi, MS Stark, E Hacker, LG Aoude, ... Pigment cell & melanoma research 24 (3), 525-537, 2011 | 208 | 2011 |
Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell … RJ Young, K Waldeck, C Martin, JH Foo, DP Cameron, L Kirby, H Do, ... Pigment cell & melanoma research 27 (4), 590-600, 2014 | 204 | 2014 |
Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma JJ Gartner, SCJ Parker, TD Prickett, K Dutton-Regester, ML Stitzel, JC Lin, ... Proceedings of the National Academy of Sciences 110 (33), 13481-13486, 2013 | 198 | 2013 |
Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma LG Aoude, AL Pritchard, CD Robles-Espinoza, K Wadt, M Harland, J Choi, ... Journal of the National Cancer Institute 107 (2), dju408, 2015 | 188 | 2015 |
The genomic landscape of cutaneous melanoma T Zhang, K Dutton‐Regester, KM Brown, NK Hayward Pigment cell & melanoma research 29 (3), 266-283, 2016 | 180 | 2016 |
MC1R is a potent regulator of PTEN after UV exposure in melanocytes J Cao, L Wan, E Hacker, X Dai, S Lenna, C Jimenez-Cervantes, Y Wang, ... Molecular cell 51 (4), 409-422, 2013 | 161 | 2013 |
Recurrent inactivating RASA2 mutations in melanoma R Arafeh, N Qutob, R Emmanuel, A Keren-Paz, J Madore, A Elkahloun, ... Nature genetics 47 (12), 1408-1410, 2015 | 123 | 2015 |
BRAF mutation status is an independent prognostic factor for resected stage IIIB and IIIC melanoma: implications for melanoma staging and adjuvant therapy AP Barbour, YH Tang, N Armour, K Dutton-Regester, L Krause, KA Loffler, ... European Journal of Cancer 50 (15), 2668-2676, 2014 | 80 | 2014 |
Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes JC Tiffen, D Gunatilake, SJ Gallagher, K Gowrishankar, A Heinemann, ... Oncotarget 6 (29), 27023, 2015 | 79 | 2015 |
Artificial intelligence in research M Musib, F Wang, MA Tarselli, R Yoho, KH Yu, RM Andrés, ... Science 357 (6346), 28-30, 2017 | 70 | 2017 |
Melanomas of unknown primary have a mutation profile consistent with cutaneous sun‐exposed melanoma K Dutton‐Regester, H Kakavand, LG Aoude, MS Stark, MG Gartside, ... Pigment cell & melanoma research 26 (6), 852-860, 2013 | 65 | 2013 |
Reviewing the somatic genetics of melanoma: from current to future analytical approaches K Dutton‐Regester, NK Hayward Pigment cell & melanoma research 25 (2), 144-154, 2012 | 63 | 2012 |
BRAF/NRAS wild-type melanoma, NF1 status and sensitivity to trametinib M Ranzani, C Alifrangis, D Perna, K Dutton-Regester, A Pritchard, ... Pigment cell & melanoma research 28 (1), 117, 2015 | 58 | 2015 |
A highly recurrent RPS27 5'UTR mutation in melanoma K Dutton-Regester, JJ Gartner, R Emmanuel, N Qutob, MA Davies, ... Oncotarget 5 (10), 2912, 2014 | 56 | 2014 |