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Richard Gordon
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Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
R Gordon, EA Albornoz, DC Christie, MR Langley, V Kumar, S Mantovani, ...
Science translational medicine 10 (465), eaah4066, 2018
5722018
The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins
V Deora, JD Lee, EA Albornoz, L McAlary, CJ Jagaraj, AAB Robertson, ...
Glia 68 (2), 407-421, 2020
1562020
Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of Parkinson's disease
N Panicker, H Saminathan, H Jin, M Neal, DS Harischandra, R Gordon, ...
Journal of Neuroscience 35 (27), 10058-10077, 2015
1502015
The complement receptor C5aR controls acute inflammation and astrogliosis following spinal cord injury
FH Brennan, R Gordon, HW Lao, PJ Biggins, SM Taylor, RJM Franklin, ...
Journal of Neuroscience 35 (16), 6517-6531, 2015
1182015
Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes
M Neal, J Luo, DS Harischandra, R Gordon, S Sarkar, H Jin, ...
Glia 66 (10), 2137-2157, 2018
1032018
A simple magnetic separation method for high-yield isolation of pure primary microglia
R Gordon, CE Hogan, ML Neal, V Anantharam, AG Kanthasamy, ...
Journal of neuroscience methods 194 (2), 287-296, 2011
1002011
Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease
R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ...
Neurobiology of disease 93, 96-114, 2016
982016
Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation
R Gordon, V Anantharam, AG Kanthasamy, A Kanthasamy
Journal of neuroinflammation 9, 1-18, 2012
932012
Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation
W Chen, SS Foo, A Zaid, TS Teng, LJ Herrero, S Wolf, K Tharmarajah, ...
Nature microbiology 2 (10), 1435-1445, 2017
912017
Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration
R Gordon, ML Neal, J Luo, MR Langley, DS Harischandra, N Panicker, ...
Nature communications 7 (1), 12932, 2016
902016
An overview of sleep and circadian dysfunction in Parkinson's disease
S Mantovani, SS Smith, R Gordon, JD O'Sullivan
Journal of Sleep Research 27 (3), e12673, 2018
832018
Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood
S Mantovani, R Gordon, JK Macmaw, CMM Pfluger, RD Henderson, ...
Journal of Neuroimmunology 276 (1-2), 213-218, 2014
772014
Antiallodynic effects of alpha lipoic acid in an optimized RR‐EAE mouse model of MS‐neuropathic pain are accompanied by attenuation of upregulated BDNF‐TrkB‐ERK signaling in …
N Khan, R Gordon, TM Woodruff, MT Smith
Pharmacology research & perspectives 3 (3), e00137, 2015
482015
Neuroprotective effect of resveratrol against methamphetamine-induced dopaminergic apoptotic cell death in a cell culture model of neurotoxicity
K Kanthasamy, R Gordon, H Jin, V Anantharam, S Ali, A G Kanthasamy, ...
Current neuropharmacology 9 (1), 49-53, 2011
462011
Inflammasomes in CNS diseases
EA Albornoz, TM Woodruff, R Gordon
Inflammasomes: Clinical and Therapeutic Implications, 41-60, 2018
402018
The ketone body β-hydroxybutyrate does not inhibit synuclein mediated inflammasome activation in microglia
V Deora, EA Albornoz, K Zhu, TM Woodruff, R Gordon
Journal of Neuroimmune Pharmacology 12, 568-574, 2017
322017
Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice
S Mantovani, R Gordon, R Li, DC Christie, V Kumar, TM Woodruff
Human Molecular Genetics 25 (9), 1780-1791, 2016
292016
p73 gene in dopaminergic neurons is highly susceptible to manganese neurotoxicity
DS Kim, H Jin, V Anantharam, R Gordon, A Kanthasamy, AG Kanthasamy
Neurotoxicology 59, 231-239, 2017
182017
Neuroinflammation as a Therapeutic Target in Neurodegenerative Diseases
R Gordon, TM Woodruff
Disease-Modifying Targets in Neurodegenerative Disorders 1, 89-132, 2017
142017
Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function
M Idris, DJ Mitchell, R Gordon, NP Sidharthan, NJ Butcher, RF Minchin
Drug Metabolism and Disposition 48 (5), 337-344, 2020
102020
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Articles 1–20