| CRISPR interference-based platform for multimodal genetic screens in human iPSC-derived neurons R Tian, MA Gachechiladze, CH Ludwig, MT Laurie, JY Hong, D Nathaniel, ... Neuron 104 (2), 239-255. e12, 2019 | 333 | 2019 |
| DHCR7: A vital enzyme switch between cholesterol and vitamin D production AV Prabhu, W Luu, D Li, LJ Sharpe, AJ Brown Progress in lipid research 64, 138-151, 2016 | 159 | 2016 |
| Cholesterol-mediated degradation of 7-dehydrocholesterol reductase switches the balance from cholesterol to vitamin D synthesis AV Prabhu, W Luu, LJ Sharpe, AJ Brown Journal of Biological Chemistry 291 (16), 8363-8373, 2016 | 133 | 2016 |
| New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis V Howe, LJ Sharpe, AV Prabhu, AJ Brown Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017 | 77 | 2017 |
| The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis AV Prabhu, LJ Sharpe, AJ Brown Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 40 | 2014 |
| Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis AV Prabhu, W Luu, LJ Sharpe, AJ Brown The Journal of Steroid Biochemistry and Molecular Biology 165, 363-368, 2017 | 36 | 2017 |
| Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features P Robbe, KE Ridout, DV Vavoulis, H Dréau, B Kinnersley, N Denny, ... Nature genetics 54 (11), 1675-1689, 2022 | 30 | 2022 |
| Overexpression of a key regulator of lipid homeostasis, Scap, promotes respiration in prostate cancer cells AV Prabhu, JR Krycer, AJ Brown FEBS letters 587 (7), 983-988, 2013 | 25 | 2013 |
| Twin enzymes, divergent control: the cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally IM Capell-Hattam, LJ Sharpe, L Qian, G Hart-Smith, AV Prabhu, AJ Brown Journal of Biological Chemistry 295 (9), 2850-2865, 2020 | 24 | 2020 |
| Functional annotation of lncRNA in high-throughput screening CW Yip, DM Sivaraman, AV Prabhu, JW Shin Essays in biochemistry 65 (4), 761-773, 2021 | 15 | 2021 |
| Antisense-oligonucleotide-mediated perturbation of long non-coding RNA reveals functional features in stem cells and across cell types CW Yip, CC Hon, K Yasuzawa, DM Sivaraman, JA Ramilowski, ... Cell reports 41 (13), 2022 | 12 | 2022 |
| A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 AV Prabhu, I Kang, R De Pace, CA Wassif, H Fujiwara, P Kell, X Jiang, ... BMC biology 19, 1-12, 2021 | 11 | 2021 |
| Navigating the shallows and rapids of cholesterol synthesis downstream of HMGCR LJ Sharpe, V Howe, AV Prabhu, W Luu, AJ Brown Journal of nutritional science and vitaminology 61 (Supplement), S154-S156, 2015 | 5 | 2015 |
| Measuring activity of cholesterol synthesis enzymes using gas chromatography/mass spectrometry AV Prabhu, W Luu, AJ Brown Cholesterol Homeostasis: Methods and Protocols, 211-219, 2017 | 3 | 2017 |
| The high-throughput perturbation of long non-coding RNA reveals functional features in stem cells and across cell-types CW Yip, CC Hon, K Yasuzawa, DM Sivaraman, JA Ramilowski, ... bioRxiv, 2022.02. 16.480297, 2022 | 1 | 2022 |
| Cholesterol‐Mediated Degradation of 7‐Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis LJ Sharpe, AV Prabhu, W Luu, AJ Brown The FASEB Journal 30, 1064.1-1064.1, 2016 | 1 | 2016 |
| The interplay between cholesterol and vitamin D biosynthesis A Prabhu, W Luu, L Sharpe, A Brown The FASEB Journal 29, 568.36, 2015 | 1 | 2015 |
| The regulation of DHCR7-a key enzyme in cholesterol synthesis A Prabhu UNSW Sydney, 2016 | | 2016 |
Laura SharpeUniversity of New South WalesVerified email at unsw.edu.au
