| Noninvasive MR imaging–guided focal opening of the blood-brain barrier in rabbits K Hynynen, N McDannold, N Vykhodtseva, FA Jolesz Radiology 220 (3), 640-646, 2001 | 1626 | 2001 |
| A randomized trial of focused ultrasound thalamotomy for essential tremor WJ Elias, N Lipsman, WG Ondo, P Ghanouni, YG Kim, W Lee, M Schwartz, ... New England Journal of Medicine 375 (8), 730-739, 2016 | 1037 | 2016 |
| Apparatus and method for intra-cardiac ablation of arrhythmias FI Marcus, KH Hynynen US Patent 5,295,484, 1994 | 911 | 1994 |
| MR imaging-guided focused ultrasound surgery of fibroadenomas in the breast: a feasibility study K Hynynen, O Pomeroy, DN Smith, PE Huber, NJ McDannold, ... Radiology 219 (1), 176-185, 2001 | 852 | 2001 |
| Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound N Lipsman, Y Meng, AJ Bethune, Y Huang, B Lam, M Masellis, ... Nature communications 9 (1), 2336, 2018 | 830 | 2018 |
| Overview of therapeutic ultrasound applications and safety considerations DL Miller, NB Smith, MR Bailey, GJ Czarnota, K Hynynen, IRS Makin, ... Journal of ultrasound in medicine 31 (4), 623-634, 2012 | 822 | 2012 |
| MR imaging–guided focused ultrasound surgery of uterine leiomyomas: a feasibility study CMC Tempany, EA Stewart, N McDannold, BJ Quade, FA Jolesz, ... Radiology 226 (3), 897-905, 2003 | 808 | 2003 |
| Local and reversible blood–brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications K Hynynen, N McDannold, NA Sheikov, FA Jolesz, N Vykhodtseva Neuroimage 24 (1), 12-20, 2005 | 788 | 2005 |
| Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood–brain barrier disruption M Kinoshita, N McDannold, FA Jolesz, K Hynynen Proceedings of the National Academy of Sciences 103 (31), 11719-11723, 2006 | 747 | 2006 |
| Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles N Sheikov, N McDannold, N Vykhodtseva, F Jolesz, K Hynynen Ultrasound in medicine & biology 30 (7), 979-989, 2004 | 705 | 2004 |
| Transcranial magnetic resonance imaging–guided focused ultrasound surgery of brain tumors: initial findings in 3 patients N McDannold, GT Clement, P Black, F Jolesz, K Hynynen Neurosurgery 66 (2), 323-332, 2010 | 669 | 2010 |
| MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study N Lipsman, ML Schwartz, Y Huang, L Lee, T Sankar, M Chapman, ... The Lancet Neurology 12 (5), 462-468, 2013 | 628 | 2013 |
| Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI‐guided focused ultrasound LH Treat, N McDannold, N Vykhodtseva, Y Zhang, K Tam, K Hynynen International journal of cancer 121 (4), 901-907, 2007 | 615 | 2007 |
| A non-invasive method for focusing ultrasound through the human skull GT Clement, K Hynynen Physics in medicine & biology 47 (8), 1219, 2002 | 567 | 2002 |
| Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium N Sheikov, N McDannold, S Sharma, K Hynynen Ultrasound in medicine & biology 34 (7), 1093-1104, 2008 | 551 | 2008 |
| Demonstration of potential noninvasive ultrasound brain therapy through an intact skull K Hynynen, FA Jolesz Ultrasound in medicine & biology 24 (2), 275-283, 1998 | 537 | 1998 |
| Blood-brain barrier opening in primary brain tumors with non-invasive MR-guided focused ultrasound: a clinical safety and feasibility study T Mainprize, N Lipsman, Y Huang, Y Meng, A Bethune, S Ironside, ... Scientific reports 9 (1), 321, 2019 | 522 | 2019 |
| Targeted disruption of the blood–brain barrier with focused ultrasound: association with cavitation activity N McDannold, N Vykhodtseva, K Hynynen Physics in Medicine & Biology 51 (4), 793, 2006 | 521 | 2006 |
| The threshold for thermally significant cavitation in dog's thigh muscle in vivo K Hynynen Ultrasound in medicine & biology 17 (2), 157-169, 1991 | 513 | 1991 |
| Chemotherapy delivery issues in central nervous system malignancy: a reality check LL Muldoon, C Soussain, K Jahnke, C Johanson, T Siegal, QR Smith, ... Journal of clinical oncology 25 (16), 2295-2305, 2007 | 477 | 2007 |
