Mary Speir
Mary Speir
Hudson Institute of Medical Research
Verified email at
Cited by
Cited by
Flipping the dogma–phosphatidylserine in non-apoptotic cell death
I Shlomovitz, M Speir, M Gerlic
Cell Communication and Signaling 17 (1), 1-12, 2019
Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis
M Speir, KE Lawlor, SP Glaser, G Abraham, S Chow, A Vogrin, ...
Nature microbiology 1 (3), 1-9, 2016
Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation
P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhelm, S Dhital, ...
Nature Microbiology 5 (11), 1418-1427, 2020
The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils
AA D’Cruz, M Speir, M Bliss-Moreau, S Dietrich, S Wang, AA Chen, ...
Science signaling 11 (546), eaao1716, 2018
Necroptosis directly induces the release of full‐length biologically active IL‐33 in vitro and in an inflammatory disease model
I Shlomovitz, Z Erlich, M Speir, S Zargarian, N Baram, M Engler, ...
The FEBS Journal 286 (3), 507-522, 2019
Antibiotic regimen based on population analysis of residing persister cells eradicates Staphylococcus epidermidis biofilms
S Yang, ID Hay, DR Cameron, M Speir, B Cui, F Su, AY Peleg, T Lithgow, ...
Scientific reports 5 (1), 1-11, 2015
Ptpn6 inhibits caspase-8-and Ripk3/Mlkl-dependent inflammation
M Speir, CJ Nowell, AA Chen, JA O’Donnell, IS Shamie, PR Lakin, ...
Nature immunology 21 (1), 54-64, 2020
RIP-roaring inflammation: RIPK1 and RIPK3 driven NLRP3 inflammasome activation and autoinflammatory disease
M Speir, KE Lawlor
Seminars in Cell & Developmental Biology 109, 114-124, 2021
Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins
M Speir, A Authier-Hall, CR Brooks, KJ Farrand, BJ Compton, ...
Scientific reports 7 (1), 1-12, 2017
Legionella pneumophila Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of Flagellin
M Speir, A Vogrin, A Seidi, G Abraham, S Hunot, Q Han, GW Dorn, ...
Frontiers in cellular and infection microbiology 7, 35, 2017
Engaging natural killer T cells as ‘Universal Helpers’ for vaccination
M Speir, IF Hermans, R Weinkove
Drugs 77 (1), 1-15, 2017
Programmed cell death in Legionella infection
M Speir, JE Vince, T Naderer
Future Microbiology 9 (1), 107-118, 2014
Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist
BJ Compton, KJ Farrand, C Tang, TL Osmond, M Speir, A Authier-Hall, ...
Organic & Biomolecular Chemistry 17 (5), 1225-1237, 2019
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
DS Simpson, J Pang, A Weir, IY Kong, M Fritsch, M Rashidi, JP Cooney, ...
Immunity 55 (3), 423-441. e9, 2022
Targeting RIP kinases in chronic inflammatory disease
M Speir, TM Djajawi, SA Conos, H Tye, KE Lawlor
Biomolecules 11 (5), 646, 2021
The Australasian Cell Death Society (ACDS): celebrating 50 years of Australasian cell death research
M Speir, AH Chan, DS Simpson, T Khan, TL Saunders, IKH Poon, ...
Immunology and Cell Biology 100 (1), 9-14, 2022
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