Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis M Speir, KE Lawlor, SP Glaser, G Abraham, S Chow, A Vogrin, ... Nature microbiology 1 (3), 1-9, 2016 | 41 | 2016 |
Antibiotic regimen based on population analysis of residing persister cells eradicates Staphylococcus epidermidis biofilms S Yang, ID Hay, DR Cameron, M Speir, B Cui, F Su, AY Peleg, T Lithgow, ... Scientific reports 5 (1), 1-11, 2015 | 31 | 2015 |
Flipping the dogma–phosphatidylserine in non-apoptotic cell death I Shlomovitz, M Speir, M Gerlic Cell Communication and Signaling 17 (1), 1-12, 2019 | 26 | 2019 |
Necroptosis directly induces the release of full‐length biologically active IL‐33 in vitro and in an inflammatory disease model I Shlomovitz, Z Erlich, M Speir, S Zargarian, N Baram, M Engler, ... The FEBS journal 286 (3), 507-522, 2019 | 21 | 2019 |
The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils AA D’Cruz, M Speir, M Bliss-Moreau, S Dietrich, S Wang, AA Chen, ... Science signaling 11 (546), 2018 | 16 | 2018 |
Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin M Speir, A Vogrin, A Seidi, G Abraham, S Hunot, Q Han, GW Dorn, ... Frontiers in cellular and infection microbiology 7, 35, 2017 | 12 | 2017 |
Engaging natural killer T cells as ‘Universal Helpers’ for vaccination M Speir, IF Hermans, R Weinkove Drugs 77 (1), 1-15, 2017 | 11 | 2017 |
Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins M Speir, A Authier-Hall, CR Brooks, KJ Farrand, BJ Compton, ... Scientific reports 7 (1), 1-12, 2017 | 10 | 2017 |
Programmed cell death in Legionella infection M Speir, JE Vince, T Naderer Future microbiology 9 (1), 107-118, 2014 | 10 | 2014 |
Ptpn6 inhibits caspase-8-and Ripk3/Mlkl-dependent inflammation M Speir, CJ Nowell, AA Chen, JA O’Donnell, IS Shamie, PR Lakin, ... Nature immunology 21 (1), 54-64, 2020 | 6 | 2020 |
Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist BJ Compton, KJ Farrand, C Tang, TL Osmond, M Speir, A Authier-Hall, ... Organic & biomolecular chemistry 17 (5), 1225-1237, 2019 | 3 | 2019 |
Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhelm, S Dhital, ... Nature Microbiology 5 (11), 1418-1427, 2020 | 2 | 2020 |
RIP-roaring inflammation: RIPK1 and RIPK3 driven NLRP3 inflammasome activation and autoinflammatory disease M Speir, KE Lawlor Seminars in Cell & Developmental Biology, 2020 | | 2020 |