| Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration ES Musiek, MM Lim, G Yang, AQ Bauer, L Qi, Y Lee, JH Roh, ... The Journal of clinical investigation 123 (12), 2013 | 467 | 2013 |
| Anti-ApoE antibody given after plaque onset decreases Aβ accumulation and improves brain function in a mouse model of Aβ amyloidosis F Liao, Y Hori, E Hudry, AQ Bauer, H Jiang, TE Mahan, KB Lefton, ... Journal of Neuroscience 34 (21), 7281-7292, 2014 | 131 | 2014 |
| Core features of frontotemporal dementia recapitulated in progranulin knockout mice N Ghoshal, JT Dearborn, DF Wozniak, NJ Cairns Neurobiology of disease 45 (1), 395-408, 2012 | 121 | 2012 |
| Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target Y Li, Y Xu, BA Benitez, MS Nagree, JT Dearborn, X Jiang, MA Guzman, ... Proceedings of the National Academy of Sciences 116 (40), 20097-20103, 2019 | 74 | 2019 |
| An anti-neuroinflammatory that targets dysregulated glia enhances the efficacy of CNS-directed gene therapy in murine infantile neuronal ceroid lipofuscinosis SL Macauley, AMS Wong, C Shyng, DP Augner, JT Dearborn, Y Pearse, ... Journal of Neuroscience 34 (39), 13077-13082, 2014 | 68 | 2014 |
| Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function LR Stein, DF Wozniak, JT Dearborn, S Kubota, RS Apte, Y Izumi, ... Journal of Neuroscience 34 (17), 5800-5815, 2014 | 64 | 2014 |
| Synergistic effects of treating the spinal cord and brain in CLN1 disease C Shyng, HR Nelvagal, JT Dearborn, J Tyynelä, RE Schmidt, MS Sands, ... Proceedings of the National Academy of Sciences 114 (29), E5920-E5929, 2017 | 56 | 2017 |
| A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation J Chen, ME Lambo, X Ge, JT Dearborn, Y Liu, KB McCullough, RG Swift, ... Neuron 109 (23), 3775-3792. e14, 2021 | 42 | 2021 |
| Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers JT Dearborn, SK Harmon, SC Fowler, KL O’Malley, GT Taylor, MS Sands, ... Scientific reports 5 (1), 12752, 2015 | 35 | 2015 |
| Hormones in the mentally disturbed brain: steroids and peptides in the development and treatment of psychopathology GT Taylor, S Maloney, J Dearborn, J Weiss Central Nervous System Agents in Medicinal Chemistry (Formerly Current …, 2009 | 34 | 2009 |
| Motivational disturbances and effects of L-dopa administration in neurofibromatosis-1 model mice DF Wozniak, KA Diggs-Andrews, S Conyers, CM Yuede, JT Dearborn, ... PLoS One 8 (6), e66024, 2013 | 26 | 2013 |
| Loss of RBPj in postnatal excitatory neurons does not cause neurodegeneration or memory impairments in aged mice C Sato, M Turkoz, JT Dearborn, DF Wozniak, R Kopan, MR Hass PloS one 7 (10), e48180, 2012 | 24 | 2012 |
| Spinal manifestations of CLN1 disease start during the early postnatal period HR Nelvagal, JT Dearborn, JR Ostergaard, MS Sands, JD Cooper Neuropathology and applied neurobiology 47 (2), 251-267, 2021 | 15 | 2021 |
| Bone marrow transplantation alters the tremor phenotype in the murine model of globoid-cell leukodystrophy AS Reddy, DF Wozniak, NB Farber, JT Dearborn, SC Fowler, MS Sands Journal of clinical medicine 1 (1), 1-14, 2012 | 13 | 2012 |
| Histochemical localization of palmitoyl protein thioesterase-1 activity JT Dearborn, S Ramachandran, C Shyng, JY Lu, J Thornton, SL Hofmann, ... Molecular genetics and metabolism 117 (2), 210-216, 2016 | 10 | 2016 |
| Impact of hepatitis C coinfection on cognitive outcomes in HIV-infected individuals R Paul, S Letendre, J Dearborn Current Hepatitis Reports 6, 145-152, 2007 | 10 | 2007 |
| Widespread expression of a membrane-tethered version of the soluble lysosomal enzyme palmitoyl protein thioesterase-1 C Shyng, SL Macauley, JT Dearborn, MS Sands JIMD Reports, Volume 36, 85-92, 2017 | 8 | 2017 |
| Cell-autonomous expression of the acid hydrolase galactocerebrosidase CR Mikulka, JT Dearborn, BA Benitez, A Strickland, L Liu, J Milbrandt, ... Proceedings of the National Academy of Sciences 117 (16), 9032-9041, 2020 | 7 | 2020 |
| Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep HR Nelvagal, SL Eaton, SH Wang, EM Eultgen, K Takahashi, SQ Le, ... The Journal of Clinical Investigation 132 (20), 2022 | 6 | 2022 |
| Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures JT Dearborn, HR Nelvagal, NR Rensing, K Takahashi, SM Hughes, ... Scientific reports 12 (1), 11286, 2022 | 6 | 2022 |
