Graham Jackson
Graham Jackson
UCL Institute of Prion Diseases
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Cited by
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Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples
AF Hill, RJ Butterworth, S Joiner, G Jackson, MN Rossor, DJ Thomas, ...
The Lancet 353 (9148), 183-189, 1999
Location and properties of metal-binding sites on the human prion protein
GS Jackson, I Murray, LLP Hosszu, N Gibbs, JP Waltho, AR Clarke, ...
Proceedings of the National Academy of Sciences 98 (15), 8531-8535, 2001
Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations
GS Jackson, LLP Hosszu, A Power, AF Hill, J Kenney, H Saibil, ...
Science 283 (5409), 1935-1937, 1999
Strain-specific prion-protein conformation determined by metal ions
JDF Wadsworth, AF Hill, S Joiner, GS Jackson, AR Clarke, J Collinge
Nature cell biology 1 (1), 55-59, 1999
Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: implications for the mechanism of assisted protein folding
GS Jackson, RA Staniforth, DJ Halsall, T Atkinson, JJ Holbrook, ...
Biochemistry 32 (10), 2554-2563, 1993
Disease-associated prion protein oligomers inhibit the 26S proteasome
M Kristiansen, P Deriziotis, DE Dimcheff, GS Jackson, H Ovaa, ...
Molecular cell 26 (2), 175-188, 2007
Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates
A Dalrymple, EJ Wild, R Joubert, K Sathasivam, M Bj÷rkqvist, ┼ PetersÚn, ...
Journal of proteome research 6 (7), 2833-2840, 2007
Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay
JA Edgeworth, M Farmer, A Sicilia, P Tavares, J Beck, T Campbell, ...
The Lancet 377 (9764), 487-493, 2011
Structural mobility of the human prion protein probed by backbone hydrogen exchange
LLP Hosszu, NJ Baxter, GS Jackson, A Power, AR Clarke, JP Waltho, ...
Nature structural biology 6 (8), 740-743, 1999
Superoxide Dismutase 1 and tgSOD1G93A Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis
R Chia, MH Tattum, S Jones, J Collinge, EMC Fisher, GS Jackson
PloS one 5 (5), e10627, 2010
Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin
S Cronier, N Gros, MH Tattum, GS Jackson, AR Clarke, J Collinge, ...
Biochemical Journal 416 (2), 297-305, 2008
XAFS study of the high-affinity copper-binding site of human PrP91–231 and its low-resolution structure in solution
SS Hasnain, LM Murphy, RW Strange, JG Grossmann, AR Clarke, ...
Journal of molecular biology 311 (3), 467-473, 2001
Regional heterogeneity of cellular prion protein isoforms in the mouse brain
V Beringue, G Mallinson, M Kaisar, M Tayebi, Z Sattar, G Jackson, ...
Brain 126 (9), 2065-2073, 2003
Multiple folding pathways for heterologously expressed human prion protein
GS Jackson, AF Hill, C Joseph, L Hosszu, A Power, JP Waltho, AR Clarke, ...
Biochimica et Biophysica Acta (BBA)-Protein Structure and Moleculará…, 1999
Crystal structure of human prion protein bound to a therapeutic antibody
SV Antonyuk, CR Trevitt, RW Strange, GS Jackson, D Sangar, ...
Proceedings of the National Academy of Sciences 106 (8), 2554-2558, 2009
Mammalian prion proteins
GS Jackson, AR Clarke
Current opinion in structural biology 10 (1), 69-74, 2000
An enzyme–detergent method for effective prion decontamination of surgical steel
GS Jackson, E McKintosh, E Flechsig, K Prodromidou, P Hirsch, ...
Journal of General Virology 86 (3), 869-878, 2005
The role of the cellular prion protein in the immune system
JD Isaacs, GS Jackson, DM Altmann
Clinical & Experimental Immunology 146 (1), 1-8, 2006
Recombinant prion protein does not possess SOD-1 activity
S Jones, M Batchelor, D Bhelt, AR Clarke, J Collinge, GS Jackson
Biochemical Journal 392 (2), 309-312, 2005
Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4
MA Wells, C Jelinska, LLP Hosszu, CJ Craven, AR Clarke, J Collinge, ...
Biochemical Journal 400 (3), 501-510, 2006
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