| Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics RL Summers, MN Nash, RE Martin Cellular and Molecular Life Sciences 69, 1967-1995, 2012 | 96 | 2012 |
| Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter RL Summers, A Dave, TJ Dolstra, S Bellanca, RV Marchetti, MN Nash, ... Proceedings of the National Academy of Sciences 111 (17), E1759-E1767, 2014 | 77 | 2014 |
| Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum … VK Zishiri, MC Joshi, R Hunter, K Chibale, PJ Smith, RL Summers, ... Journal of medicinal chemistry 54 (19), 6956-6968, 2011 | 77 | 2011 |
| Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents S Gemma, C Camodeca, M Brindisi, S Brogi, G Kukreja, S Kunjir, ... Journal of medicinal chemistry 55 (23), 10387-10404, 2012 | 70 | 2012 |
| The natural function of the malaria parasite’s chloroquine resistance transporter SH Shafik, SA Cobbold, K Barkat, SN Richards, NS Lancaster, M Llinás, ... Nature communications 11 (1), 3922, 2020 | 68 | 2020 |
| Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure–activity relationships, in vivo studies, and preliminary toxicity profiling S Gemma, C Camodeca, S Sanna Coccone, BP Joshi, M Bernetti, ... Journal of medicinal chemistry 55 (15), 6948-6967, 2012 | 52 | 2012 |
| Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites S Bellanca, RL Summers, M Meyrath, A Dave, MN Nash, M Dittmer, ... Journal of Biological Chemistry 289 (52), 36336-36351, 2014 | 48 | 2014 |
| Quinine Dimers Are Potent Inhibitors of the Plasmodium falciparum Chloroquine Resistance Transporter and Are Active against Quinoline-Resistant P. falciparum CA Hrycyna, RL Summers, AM Lehane, MM Pires, H Namanja, K Bohn, ... ACS chemical biology 9 (3), 722-730, 2014 | 44 | 2014 |
| Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ... Cell chemical biology 29 (2), 191-201. e8, 2022 | 41 | 2022 |
| Biochemical characterization and chemical inhibition of PfATP4-associated Na+-ATPase activity in Plasmodium falciparum membranes JEO Rosling, MC Ridgway, RL Summers, K Kirk, AM Lehane Journal of Biological Chemistry 293 (34), 13327-13337, 2018 | 41 | 2018 |
| Functional characteristics of the malaria parasite's" chloroquine resistance transporter": implications for chemotherapy RL Summers, RE Martin Virulence 1 (4), 304-308, 2010 | 35 | 2010 |
| A series of structurally simple chloroquine chemosensitizing dibemethin derivatives that inhibit chloroquine transport by PfCRT VK Zishiri, R Hunter, PJ Smith, D Taylor, R Summers, K Kirk, RE Martin, ... European journal of medicinal chemistry 46 (5), 1729-1742, 2011 | 34 | 2011 |
| Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's … DA van Schalkwyk, MN Nash, SH Shafik, RL Summers, AM Lehane, ... The Journal of infectious diseases 213 (5), 800-810, 2016 | 31 | 2016 |
| 1H-NMR metabolite profiles of different strains of Plasmodium falciparum R Teng, AM Lehane, M Winterberg, SH Shafik, RL Summers, RE Martin, ... Bioscience reports 34 (6), e00150, 2014 | 30 | 2014 |
| Chlorpheniramine Analogues Reverse Chloroquine Resistance in Plasmodium falciparum by Inhibiting PfCRT KJ Deane, RL Summers, AM Lehane, RE Martin, RA Barrow ACS medicinal chemistry letters 5 (5), 576-581, 2014 | 26 | 2014 |
| Inferring a complete genotype-phenotype map from a small number of measured phenotypes ZR Sailer, SH Shafik, RL Summers, A Joule, A Patterson-Robert, ... PLoS computational biology 16 (9), e1008243, 2020 | 12 | 2020 |
| Quantitative imaging of intraerythrocytic hemozoin by transient absorption microscopy AJ Chen, KC Huang, S Bopp, R Summers, P Dong, Y Huang, C Zong, ... Journal of Biomedical Optics 25 (1), 014507-014507, 2020 | 8 | 2020 |
| Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation S Bopp, CFA Pasaje, RL Summers, P Magistrado-Coxen, KA Schindler, ... Nature Communications 14 (1), 1455, 2023 | 7 | 2023 |
| Synthesis and biological evaluation of benzhydryl-based antiplasmodial agents possessing Plasmodium falciparum chloroquine resistance transporter (PfCRT) inhibitory activity N Relitti, S Federico, L Pozzetti, S Butini, S Lamponi, D Taramelli, ... European Journal of Medicinal Chemistry 215, 113227, 2021 | 6 | 2021 |
| Identification of the Plasmodium falciparum acetyl-CoA synthetase as an emerging antiplasmodial drug target RL Summers, M Vanaerschot, JM Murithi, CF Pasaje, MR Luth, ... American Journal Of Tropical Medicine And Hygiene 101, 476-477, 2019 | 1 | 2019 |
Rowena MartinThe Australian National UniversityVerified email at anu.edu.au
