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Francesca Rossiello
Francesca Rossiello
Staff scientist at the FIRC Institute of Molecular Oncology Foundation (IFOM), Milan
Verified email at ifom.eu
Title
Cited by
Cited by
Year
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
M Fumagalli, F Rossiello, M Clerici, S Barozzi, D Cittaro, JM Kaplunov, ...
Nature cell biology 14 (4), 355-365, 2012
8872012
Telomere dysfunction in ageing and age-related diseases
F Rossiello, D Jurk, JF Passos, F d’Adda di Fagagna
Nature Cell Biology 24 (2), 135-147, 2022
2632022
Stable cellular senescence is associated with persistent DDR activation
M Fumagalli, F Rossiello, C Mondello, FA di Fagagna
PloS one 9 (10), e110969, 2014
1692014
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing
F Rossiello, U Herbig, MP Longhese, M Fumagalli, FA di Fagagna
Current opinion in genetics & development 26, 89-95, 2014
1462014
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome
J Aguado, A Sola-Carvajal, V Cancila, G Revêchon, PF Ong, ...
Nature communications 10 (1), 4990, 2019
1032019
DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs
F Rossiello, J Aguado, S Sepe, F Iannelli, Q Nguyen, S Pitchiaya, ...
Nature communications 8, 13980, 2017
1012017
From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond
F Michelini, AP Jalihal, S Francia, C Meers, ZT Neeb, F Rossiello, U Gioia, ...
Chemical reviews 118 (8), 4365-4403, 2018
832018
Identification of fifteen novel germline variants in the BRCA1 3′ UTR reveals a variant in a breast cancer case that introduces a functional miR‐103 target site
BL Brewster, F Rossiello, JD French, SL Edwards, M Wong, A Wronski, ...
Human mutation 33 (12), 1665-1675, 2012
622012
Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury
AK Uryga, MOJ Grootaert, AM Garrido, S Oc, K Foote, J Chappell, ...
Communications Biology 4 (1), 611, 2021
352021
DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging
S Sepe, F Rossiello, V Cancila, F Iannelli, V Matti, G Cicio, M Cabrini, ...
EMBO reports 23 (2), e53658, 2022
302022
Target-enrichment sequencing for detailed characterization of small RNAs
Q Nguyen, J Aguado, F Iannelli, AM Suzuki, F Rossiello, ...
Nature protocols 13 (4), 768-786, 2018
92018
RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci
F Michelini, F Rossiello, F d’Adda di Fagagna, S Francia
Nature Protocols 14 (5), 1489-1508, 2019
82019
ImmunoFISH for Adherent Cultured Mammalian Cells
F Rossiello, M Fumagalli, FA di Fagagna
Bio-protocol 3 (24), e999-e999, 2013
12013
Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs
I Rosso, C Jones-Weinert, F Rossiello, M Cabrini, S Brambillasca, ...
Nature Communications 14 (1), 7086, 2023
2023
P1327: INHIBITING TELOMERIC DNA DAMAGE RESPONSE AS A NEW THERAPEUTIC STRATEGY TO REJUVENATE THE AGEING HEMATOPOIETIC SYSTEM
A Oppezzo, S Sepe, F Rossiello, A Conti, E Marinelli, S Boggio, ADI Lillo, ...
HemaSphere 7 (S3), e6000984, 2023
2023
Therapeutic oligonucleotides
FDA Di Fagagna, F Rossiello, J Aguado, C Jones-Weinert
US Patent App. 17/065,409, 2021
2021
RNA products and uses thereof
FDA Di Fagagna, S Francia, F Michelini, F Rossiello
US Patent 10,240,154, 2019
2019
Therapeutic oligonucleotides
FDA Di Fagagna, F Rossiello, J Aguado, C Jones-Weinert
US Patent App. 15/748,133, 2018
2018
STUDY ON THE GENETIC PREDISPOSITION TO BREAST CANCER AND THE DNA DAMAGE RESPONSE AT TELOMERES AND IN CELLULAR SENESCENCE
F Rossiello
Istituto Lombardo-Accademia di Scienze e Lettere-Rendiconti di Scienze, 2016
2016
PERSISTENT DNA DAMAGE AT TELOMERES, CAUSED BY TRF2-MEDIATED DNA REPAIR INHIBITION, TRIGGERS CELLULAR SENESCENCE AND IS ASSOCIATED WITH PRIMATES AGEING
F Rossiello
Università degli Studi di Milano, 2014
2014
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