|Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance|
A Burgess, S Vigneron, E Brioudes, JC Labbé, T Lorca, A Castro
Proceedings of the National Academy of Sciences 107 (28), 12564-12569, 2010
|Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events|
RA McCloy, S Rogers, CE Caldon, T Lorca, A Castro, A Burgess
Cell Cycle 13 (9), 1400-1412, 2014
|The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A|
A Gharbi-Ayachi, JC Labbé, A Burgess, S Vigneron, JM Strub, E Brioudes, ...
Science 330 (6011), 1673-1677, 2010
|Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells|
L Qiu, A Burgess, DP Fairlie, H Leonard, PG Parsons, BG Gabrielli
Molecular biology of the cell 11 (6), 2069-2083, 2000
|Clinical overview of MDM2/X-targeted therapies|
A Burgess, KM Chia, S Haupt, D Thomas, Y Haupt, E Lim
Frontiers in oncology 6, 7, 2016
|Up-regulation of p21WAF1/CIP1 by histone deacetylase inhibitors reduces their cytotoxicity|
AJ Burgess, S Pavey, R Warrener, LJK Hunter, TJ Piva, EA Musgrove, ...
Molecular pharmacology 60 (4), 828-837, 2001
|Greatwall maintains mitosis through regulation of PP2A|
S Vigneron, E Brioudes, A Burgess, JC Labbé, T Lorca, A Castro
The EMBO journal 28 (18), 2786-2793, 2009
|Tumor cell‐specific cytotoxicity by targeting cell cycle checkpoints|
R Warrener, H Beamish, A Burgess, NJ Waterhouse, N Giles, DP Fairlie, ...
The FASEB journal 17 (11), 1-21, 2003
|Histone deacetylase inhibitors specifically kill nonproliferating tumour cells|
A Burgess, A Ruefli, H Beamish, R Warrener, N Saunders, R Johnstone, ...
Oncogene 23 (40), 6693-6701, 2004
|Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis|
C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ...
Science translational medicine 9 (384), 2017
|Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts|
H Brinkmann, AL Dahler, C Popa, MM Serewko, PG Parsons, BG Gabrielli, ...
Journal of Biological Chemistry 276 (25), 22491-22499, 2001
|Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle|
T Lorca, C Bernis, S Vigneron, A Burgess, E Brioudes, JC Labbé, ...
Journal of Cell Science 123 (13), 2281-2291, 2010
|The EBNA-3 gene family proteins disrupt the G2/M checkpoint|
KG Krauer, A Burgess, M Buck, J Flanagan, TB Sculley, B Gabrielli
Oncogene 23 (7), 1342-1353, 2004
|Mechanism of mitosis-specific activation of MEK1|
A Harding, N Giles, A Burgess, JF Hancock, BG Gabrielli
Journal of Biological Chemistry 278 (19), 16747-16754, 2003
|Chfr interacts and colocalizes with TCTP to the mitotic spindle|
A Burgess, JC Labbe, S Vigneron, N Bonneaud, JM Strub, ...
Oncogene 27 (42), 5554-5566, 2008
|Pin1 stabilizes Emi1 during G2 phase by preventing its association with SCFβtrcp|
C Bernis, S Vigneron, A Burgess, JC Labbé, D Fesquet, A Castro, T Lorca
EMBO reports 8 (1), 91-98, 2007
|Quantitative live imaging of endogenous DNA replication in mammalian cells|
A Burgess, T Lorca, A Castro
PloS one 7 (9), e45726, 2012
|Characterization of the mechanisms controlling Greatwall activity|
S Vigneron, A Gharbi-Ayachi, AA Raymond, A Burgess, JC Labbé, ...
Molecular and Cellular Biology 31 (11), 2262-2275, 2011
|Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer|
A Chou, D Froio, AM Nagrial, A Parkin, KJ Murphy, VT Chin, D Wohl, ...
Gut 67 (12), 2142-2155, 2018
|Global phosphoproteomic mapping of early mitotic exit in human cells identifies novel substrate dephosphorylation motifs|
RA McCloy, BL Parker, S Rogers, R Chaudhuri, V Gayevskiy, NJ Hoffman, ...
Molecular & Cellular Proteomics 14 (8), 2194-2212, 2015