Differential GLP-1R binding and activation by peptide and non-peptide agonists X Zhang, MJ Belousoff, P Zhao, AJ Kooistra, TT Truong, SY Ang, ... Molecular Cell 80 (3), 485-500. e7, 2020 | 121 | 2020 |
Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity … YL Liang, MJ Belousoff, MM Fletcher, X Zhang, M Khoshouei, G Deganutti, ... ACS pharmacology & translational science 3 (2), 263-284, 2020 | 74 | 2020 |
Engineering of Candida glabrata Ketoreductase 1 for Asymmetric Reduction of α-Halo Ketones F Qin, B Qin, T Mori, Y Wang, L Meng, X Zhang, X Jia, I Abe, S You ACS Catalysis 6 (9), 6135-6140, 2016 | 57 | 2016 |
Studies on the stability of salvianolic acid B as potential drug material LN Zhou, X Zhang, WZ Xu, XN Ma, Z Jia, YM Zheng, S You Phytochemical Analysis 22 (4), 378-384, 2011 | 44 | 2011 |
Routine sub-2.5 Å cryo-EM structure determination of GPCRs R Danev, M Belousoff, YL Liang, X Zhang, F Eisenstein, D Wootten, ... Nature Communications 12 (1), 4333, 2021 | 42 | 2021 |
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation G Deganutti, YL Liang, X Zhang, M Khoshouei, L Clydesdale, ... Nature Communications 13 (1), 92, 2022 | 40 | 2022 |
Evolving cryo-EM structural approaches for GPCR drug discovery X Zhang, RM Johnson, I Drulyte, L Yu, A Kotecha, R Danev, D Wootten, ... Structure 29 (9), 963-974. e6, 2021 | 39 | 2021 |
Prelog and anti-Prelog stereoselectivity of two ketoreductases from Candida glabrata P Liang, B Qin, M Mu, X Zhang, X Jia, S You Biotechnology letters 35, 1469-1473, 2013 | 36 | 2013 |
Structure and dynamics of semaglutide-and taspoglutide-bound GLP-1R-Gs complexes X Zhang, MJ Belousoff, YL Liang, R Danev, PM Sexton, D Wootten Cell reports 36 (2), 2021 | 33 | 2021 |
Directed evolution of Candida antarctica lipase B for kinetic resolution of profen esters B Qin, P Liang, X Jia, X Zhang, M Mu, XY Wang, GZ Ma, DN Jin, S You Catalysis Communications 38, 1-5, 2013 | 33 | 2013 |
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide R Chang, X Zhang, A Qiao, A Dai, MJ Belousoff, Q Tan, L Shao, L Zhong, ... Journal of Biological Chemistry 295 (28), 9313-9325, 2020 | 31 | 2020 |
Cytochalasin B induces apoptosis through the mitochondrial apoptotic pathway in HeLa human cervical carcinoma cells J Hwang, M Yi, X Zhang, Y Xu, JH Jung, DK Kim Oncology reports 30 (4), 1929-1935, 2013 | 29 | 2013 |
Synthesis, optical properties and preliminary in vitro photodynamic effect of pyridyl and quinoxalyl substituted chlorins J Li, X Zhang, Y Liu, I Yoon, DK Kim, JG Yin, JJ Wang, YK Shim Bioorganic & Medicinal Chemistry 23 (8), 1684-1690, 2015 | 21 | 2015 |
An insight into the curdione biotransformation pathway by Aspergillus niger Y Chen, L Zhang, B Qin, X Zhang, X Jia, X Wang, D Jin, S You Natural Product Research 28 (7), 454-460, 2014 | 21 | 2014 |
Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor RM Johnson, X Zhang, SJ Piper, TJ Nettleton, TH Vandekolk, ... Biochemical and Biophysical Research Communications 578, 84-90, 2021 | 19 | 2021 |
New insights into the structure and function of class B1 GPCRs BP Cary, X Zhang, J Cao, RM Johnson, SJ Piper, EJ Gerrard, D Wootten, ... Endocrine reviews 44 (3), 492-517, 2023 | 17 | 2023 |
A novel bispidinone analog induces S‑phase cell cycle arrest and apoptosis in HeLa human cervical carcinoma cells X Yi, X Zhang, H Jeong, YM Shin, DH Park, S You, DK Kim Oncology reports 33 (3), 1526-1532, 2015 | 11 | 2015 |
“Mirror-image” manipulation of curdione stereoisomer scaffolds by chemical and biological approaches: development of a sesquiterpenoid library B Qin, Y Li, L Meng, J Ouyang, D Jin, L Wu, X Zhang, X Jia, S You Journal of Natural Products 78 (2), 272-278, 2015 | 11 | 2015 |
A novel cromakalim analogue induces cell cycle arrest and apoptosis in human cervical carcinoma HeLa cells through the caspase-and mitochondria-dependent pathway X Zhang, J Zhao, S Kang, M Yi, S You, DS Shin, DK Kim International journal of oncology 39 (6), 1609-1617, 2011 | 11 | 2011 |
Effect of a bispidinone analog on mitochondria‑mediated apoptosis in HeLa cells M Yi, P Parthiban, J Hwang, X Zhang, H Jeong, DH Park, DK Kim International Journal of Oncology 44 (1), 327-335, 2014 | 10 | 2014 |