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Hisham Abdelmotilib, MD, PhD
Hisham Abdelmotilib, MD, PhD
Neurology resident at University of Iowa Hospitals and Clinics
Verified email at uiowa.edu
Title
Cited by
Cited by
Year
Leucine-rich repeat kinase 2 (LRRK2) pharmacological inhibition abates α-synuclein gene-induced neurodegeneration
JPL Daher, HA Abdelmotilib, X Hu, LA Volpicelli-Daley, MS Moehle, ...
Journal of Biological Chemistry 290 (32), 19433-19444, 2015
2122015
G2019S-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons
LA Volpicelli-Daley, H Abdelmotilib, Z Liu, L Stoyka, JPL Daher, ...
Journal of Neuroscience 36 (28), 7415-7427, 2016
1952016
α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration
H Abdelmotilib, T Maltbie, V Delic, Z Liu, X Hu, KB Fraser, MS Moehle, ...
Neurobiology of disease 105, 84-98, 2017
1702017
The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins
MS Moehle, JPL Daher, TD Hull, R Boddu, HA Abdelmotilib, J Mobley, ...
Human molecular genetics 24 (15), 4250-4267, 2015
792015
Sensitivity and specificity of Phospho‐Ser129 α‐synuclein monoclonal antibodies
V Delic, S Chandra, H Abdelmotilib, T Maltbie, S Wang, D Kem, HJ Scott, ...
Journal of Comparative Neurology 526 (12), 1978-1990, 2018
672018
Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain
E Xu, R Boddu, HA Abdelmotilib, A Sokratian, K Kelly, Z Liu, N Bryant, ...
Molecular Neurodegeneration 17, 1-19, 2022
472022
COVID-19-associated necrotizing encephalopathy presenting without active respiratory symptoms: a case report with histopathology
LA Rettenmaier, L Abdel-Wahed, H Abdelmotilib, KS Conway, ...
Journal of neurovirology 28 (1), 172-176, 2022
122022
Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain
K Kelly, A Chang, L Hastings, H Abdelmotilib, AB West
Brain research 1759, 147372, 2021
102021
Breathing new life into an old target: pulmonary disease drugs for Parkinson’s disease therapy
H Abdelmotilib, AB West
Genome Medicine 9, 1-3, 2017
72017
Cortical alpha-synuclein preformed fibrils do not affect interval timing in mice
Q Zhang, H Abdelmotilib, T Larson, C Keomanivong, M Conlon, ...
Neuroscience letters 765, 136273, 2021
52021
Corrigendum to" α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration"[Neurobiol. Dis., Volume 105 (2017) Article 84, 98]
H Abdelmotilib, T Maltbie, V Delic, Z Liu, X Hu, KB Fraser, MS Moehle, ...
Neurobiology of disease 159, 105506, 2021
12021
Pathologic α-Synuclein Species Activate LRRK2 in Pro-Inflammatory Monocyte and Macrophage Responses
E Xu, R Boddu, HA Abdelmotilib, K Kelly, A Sokratian, AS Harms, ...
bioRxiv, 2020.05. 04.077065, 2020
12020
Alpha-Synuclein Pre-Formed Fibrils Injected into Prefrontal Cortex Primarily Spread to Cortical and Subcortical Structures
MA Weber, G Kerr, R Thangavel, MM Conlon, SB Gumusoglu, K Gupta, ...
Journal of Parkinson's disease, 1-14, 2024
2024
G2019S-LRRK2 Expression Augments a-Synuclein Sequestration into Inclusions in Neurons (vol 36, pg 7415, 2016)
LA Volpicelli-Daley, H Abdelmotilib, ZLL Stoyka, JPL Daher, ...
JOURNAL OF NEUROSCIENCE 42 (4), 718-718, 2022
2022
alpha-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration (vol 105, 84, 98, 2017)
H Abdelmotilib, T Maltbie, V Delic, Z Liu, X Hu, KB Fraser, MS Moehle, ...
NEUROBIOLOGY OF DISEASE 159, 2021
2021
Mechanisms Of Leucine-Rich Repeat Kinase 2 And Alphα-Synuclein In Pathogenesis Of Parkinson Disease
H Abdelmotilib
2018
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Articles 1–16