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Thomas M. Ashhurst
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Therapeutic inflammatory monocyte modulation using immune-modifying microparticles
DR Getts, RL Terry, MT Getts, C Deffrasnes, M Müller, C van Vreden, ...
Science translational medicine 6 (219), 219ra7-219ra7, 2014
3702014
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses
M Koutsakos, LC Rowntree, L Hensen, BY Chua, CE Van De Sandt, ...
Cell Reports Medicine 2 (3), 2021
1272021
Humoral responses after second and third SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders on immunosuppressants: a cohort study
L Wieske, KPJ van Dam, M Steenhuis, EW Stalman, LYL Kummer, ...
The Lancet Rheumatology 4 (5), e338-e350, 2022
992022
Integration, exploration, and analysis of high‐dimensional single‐cell cytometry data using Spectre
TM Ashhurst, F Marsh‐Wakefield, GH Putri, AG Spiteri, D Shinko, ...
Cytometry Part A 101 (3), 237-253, 2022
872022
Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages
DR Getts, RL Terry, MT Getts, M Müller, S Rana, C Deffrasnes, ...
Journal of neuroinflammation 9, 1-8, 2012
722012
Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages
DR Getts, RL Terry, MT Getts, M Müller, S Rana, C Deffrasnes, ...
Journal of Neuroinflammation 9 (1), 246, 2012
722012
An updated guide for the perplexed: cytometry in the high-dimensional era
T Liechti, LM Weber, TM Ashhurst, N Stanley, M Prlic, S Van Gassen, ...
Nature Immunology 22 (10), 1190-1197, 2021
482021
Evaluating spectral cytometry for immune profiling in viral disease
P Niewold, TM Ashhurst, AL Smith, NJC King
Cytometry Part A 97 (11), 1165-1179, 2020
482020
Varicella zoster virus productively infects human natural killer cells and manipulates phenotype
TM Campbell, BP McSharry, M Steain, TM Ashhurst, B Slobedman, ...
PLoS pathogens 14 (4), e1006999, 2018
452018
High‐dimensional fluorescence cytometry
TM Ashhurst, AL Smith, NJC King
Current protocols in immunology 119 (1), 5.8. 1-5.8. 38, 2017
382017
IRF9 Prevents CD8+ T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection
M Huber, T Suprunenko, T Ashhurst, F Marbach, H Raifer, S Wolff, ...
Journal of virology 91 (22), 10.1128/jvi. 01219-17, 2017
322017
The plasticity of inflammatory monocyte responses to the inflamed central nervous system
TM Ashhurst, C van Vreden, P Niewold, NJC King
Cellular immunology 291 (1-2), 49-57, 2014
312014
Antiviral macrophage responses in flavivirus encephalitis
TM Ashhurst, C Van Vreden, L Munoz-Erazo, P Niewold, K Watabe, ...
Indian Journal of Medical Research 138 (5), 632-647, 2013
292013
The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes
PK West, AN McCorkindale, B Guennewig, TM Ashhurst, B Viengkhou, ...
Journal of Neuroinflammation 19 (1), 96, 2022
272022
Zika virus encephalitis in immunocompetent mice is dominated by innate immune cells and does not require T or B cells
E Hayashida, ZL Ling, TM Ashhurst, B Viengkhou, SR Jung, ...
Journal of Neuroinflammation 16, 1-15, 2019
262019
Defective inflammatory monocyte development in IRF8-deficient mice abrogates migration to the West Nile virus-infected brain
RL Terry, C Deffrasnes, DR Getts, C Minten, C Van Vreden, TM Ashhurst, ...
Journal of innate immunity 7 (1), 102-112, 2014
252014
High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease
AG Spiteri, RL Terry, CL Wishart, TM Ashhurst, IL Campbell, MJ Hofer, ...
Journal of Neuroinflammation 18, 1-24, 2021
232021
IgG3+ B cells are associated with the development of multiple sclerosis
F Marsh‐Wakefield, T Ashhurst, S Trend, HM McGuire, P Juillard, A Zinger, ...
Clinical & translational immunology 9 (5), e1133, 2020
232020
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity
W Zhang, BY Chua, KJ Selva, L Kedzierski, TM Ashhurst, ER Haycroft, ...
Nature communications 13 (1), 2774, 2022
222022
ChronoClust: Density-based clustering and cluster tracking in high-dimensional time-series data
GH Putri, MN Read, I Koprinska, D Singh, U Röhm, TM Ashhurst, ...
Knowledge-Based Systems 174, 9-26, 2019
222019
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