Therapeutic inflammatory monocyte modulation using immune-modifying microparticles DR Getts, RL Terry, MT Getts, C Deffrasnes, M Müller, C van Vreden, ... Science translational medicine 6 (219), 219ra7-219ra7, 2014 | 391 | 2014 |
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses M Koutsakos, LC Rowntree, L Hensen, BY Chua, CE Van De Sandt, ... Cell Reports Medicine 2 (3), 2021 | 151 | 2021 |
Humoral responses after second and third SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders on immunosuppressants: a cohort study L Wieske, KPJ van Dam, M Steenhuis, EW Stalman, LYL Kummer, ... The Lancet Rheumatology 4 (5), e338-e350, 2022 | 120 | 2022 |
Integration, exploration, and analysis of high‐dimensional single‐cell cytometry data using Spectre TM Ashhurst, F Marsh‐Wakefield, GH Putri, AG Spiteri, D Shinko, ... Cytometry Part A 101 (3), 237-253, 2022 | 120 | 2022 |
Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages DR Getts, RL Terry, MT Getts, M Müller, S Rana, C Deffrasnes, ... Journal of Neuroinflammation 9 (1), 246, 2012 | 75 | 2012 |
An updated guide for the perplexed: cytometry in the high-dimensional era T Liechti, LM Weber, TM Ashhurst, N Stanley, M Prlic, S Van Gassen, ... Nature Immunology 22 (10), 1190-1197, 2021 | 65 | 2021 |
Evaluating spectral cytometry for immune profiling in viral disease P Niewold, TM Ashhurst, AL Smith, NJC King Cytometry Part A 97 (11), 1165-1179, 2020 | 56 | 2020 |
Varicella zoster virus productively infects human natural killer cells and manipulates phenotype TM Campbell, BP McSharry, M Steain, TM Ashhurst, B Slobedman, ... PLoS pathogens 14 (4), e1006999, 2018 | 49 | 2018 |
The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes PK West, AN McCorkindale, B Guennewig, TM Ashhurst, B Viengkhou, ... Journal of neuroinflammation 19 (1), 96, 2022 | 45 | 2022 |
High‐dimensional fluorescence cytometry TM Ashhurst, AL Smith, NJC King Current protocols in immunology 119 (1), 5.8. 1-5.8. 38, 2017 | 40 | 2017 |
IRF9 Prevents CD8+ T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection M Huber, T Suprunenko, T Ashhurst, F Marbach, H Raifer, S Wolff, ... Journal of virology 91 (22), 10.1128/jvi. 01219-17, 2017 | 35 | 2017 |
The plasticity of inflammatory monocyte responses to the inflamed central nervous system TM Ashhurst, C van Vreden, P Niewold, NJC King Cellular immunology 291 (1-2), 49-57, 2014 | 34 | 2014 |
Antiviral macrophage responses in flavivirus encephalitis TM Ashhurst, C Van Vreden, L Munoz-Erazo, P Niewold, K Watabe, ... Indian Journal of Medical Research 138 (5), 632-647, 2013 | 33 | 2013 |
Zika virus encephalitis in immunocompetent mice is dominated by innate immune cells and does not require T or B cells E Hayashida, ZL Ling, TM Ashhurst, B Viengkhou, SR Jung, ... Journal of Neuroinflammation 16, 1-15, 2019 | 31 | 2019 |
Contribution of STAT1 to innate and adaptive immunity during type I interferon-mediated lethal virus infection SR Jung, TM Ashhurst, PK West, B Viengkhou, NJC King, IL Campbell, ... PLoS pathogens 16 (4), e1008525, 2020 | 27 | 2020 |
High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease AG Spiteri, RL Terry, CL Wishart, TM Ashhurst, IL Campbell, MJ Hofer, ... Journal of Neuroinflammation 18, 1-24, 2021 | 26 | 2021 |
IgG3+ B cells are associated with the development of multiple sclerosis F Marsh‐Wakefield, T Ashhurst, S Trend, HM McGuire, P Juillard, A Zinger, ... Clinical & translational immunology 9 (5), e1133, 2020 | 26 | 2020 |
Defective inflammatory monocyte development in IRF8-deficient mice abrogates migration to the West Nile virus-infected brain RL Terry, C Deffrasnes, DR Getts, C Minten, C Van Vreden, TM Ashhurst, ... Journal of innate immunity 7 (1), 102-112, 2014 | 26 | 2014 |
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity W Zhang, BY Chua, KJ Selva, L Kedzierski, TM Ashhurst, ER Haycroft, ... Nature Communications 13 (1), 2774, 2022 | 25 | 2022 |
ChronoClust: Density-based clustering and cluster tracking in high-dimensional time-series data GH Putri, MN Read, I Koprinska, D Singh, U Röhm, TM Ashhurst, ... Knowledge-Based Systems 174, 9-26, 2019 | 25 | 2019 |