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Lachlan D. Rash
Lachlan D. Rash
Associate Professor, School of Biomedical Sciences, The University of Queensland
Verified email at uq.edu.au - Homepage
Title
Cited by
Cited by
Year
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid‐sensitive channel in sensory neurons
S Diochot, A Baron, LD Rash, E Deval, P Escoubas, S Scarzello, ...
The EMBO journal 23 (7), 1516-1525, 2004
4332004
Pharmacology and biochemistry of spider venoms
LD Rash, WC Hodgson
Toxicon 40 (3), 225-254, 2002
4272002
The concise guide to pharmacology 2019/20: Ion channels
SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ...
British journal of pharmacology 176, S142-S228, 2019
3422019
Spider-venom peptides as therapeutics
NJ Saez, S Senff, JE Jensen, SY Er, V Herzig, LD Rash, GF King
Toxins 2 (12), 2851-2871, 2010
3332010
Tarantulas: eight-legged pharmacists and combinatorial chemists
P Escoubas, L Rash
Toxicon 43 (5), 555-574, 2004
2472004
Venomics: a new paradigm for natural products-based drug discovery
I Vetter, JL Davis, LD Rash, R Anangi, M Mobli, PF Alewood, RJ Lewis, ...
Amino acids 40, 15-28, 2011
2452011
The concise guide to pharmacology 2021/22: Ion channels
SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ...
British Journal of Pharmacology 178, S157-S245, 2021
2292021
Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a
IR Chassagnon, CA McCarthy, YKY Chin, SS Pineda, A Keramidas, ...
Proceedings of the National Academy of Sciences 114 (14), 3750-3755, 2017
1942017
Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes
F Bosmans, L Rash, S Zhu, S Diochot, M Lazdunski, P Escoubas, J Tytgat
Molecular pharmacology 69 (2), 419-429, 2006
1772006
Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli
JK Klint, S Senff, NJ Saez, R Seshadri, HY Lau, NS Bende, EAB Undheim, ...
PloS one 8 (5), e63865, 2013
1732013
The diversity of venom: the importance of behavior and venom system morphology in understanding its ecology and evolution
V Schendel, LD Rash, RA Jenner, EAB Undheim
Toxins 11 (11), 666, 2019
1682019
Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy
C Simons, LD Rash, J Crawford, L Ma, B Cristofori-Armstrong, D Miller, ...
Nature genetics 47 (1), 73-77, 2015
1452015
NaV1. 7 as a pain target–from gene to pharmacology
I Vetter, JR Deuis, A Mueller, MR Israel, H Starobova, A Zhang, LD Rash, ...
Pharmacology & therapeutics 172, 73-100, 2017
1342017
Inhibition of voltage‐gated Na+ currents in sensory neurones by the sea anemone toxin APETx2
MG Blanchard, LD Rash, S Kellenberger
British journal of pharmacology 165 (7), 2167-2177, 2012
1052012
A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a
NJ Saez, M Mobli, M Bieri, IR Chassagnon, AK Malde, R Gamsjaeger, ...
Molecular pharmacology 80 (5), 796-808, 2011
1022011
The receptor site of the spider toxin PcTx1 on the proton‐gated cation channel ASIC1a
M Salinas, LD Rash, A Baron, G Lambeau, P Escoubas, M Lazdunski
The Journal of physiology 570 (2), 339-354, 2006
1012006
Acid-sensing ion channel (ASIC) structure and function: Insights from spider, snake and sea anemone venoms
B Cristofori-Armstrong, LD Rash
Neuropharmacology 127, 173-184, 2017
922017
Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity
M Rouault, D Lachlan, P Escoubas, E Boilard, J Bollinger, B Lomonte, ...
Biochemistry 45 (18), 5800-5816, 2006
812006
Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin‐2
CI Schroeder, LD Rash, X Vila‐Farrés, KJ Rosengren, M Mobli, GF King, ...
Angewandte Chemie International Edition 53 (4), 1017-1020, 2014
792014
PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a
CA McCarthy, LD Rash, IR Chassagnon, GF King, RE Widdop
Neuropharmacology 99, 650-657, 2015
662015
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