| Inhibition of the cGAS‐STING pathway ameliorates the premature senescence hallmarks of Ataxia‐Telangiectasia brain organoids J Aguado, HK Chaggar, C Gómez‐Inclán, MR Shaker, HC Leeson, ... Aging Cell 20 (9), e13468, 2021 | 62 | 2021 |
| P2X7 receptors regulate phagocytosis and proliferation in adult hippocampal and SVZ neural progenitor cells: implications for inflammation in neurogenesis HC Leeson, MA Kasherman, T Chan-Ling, MD Lovelace, JC Brownlie, ... Stem Cells 36 (11), 1764-1777, 2018 | 44 | 2018 |
| P2X7 receptor signaling during adult hippocampal neurogenesis HC Leeson, T Chan-Ling, MD Lovelace, JC Brownlie, BJ Gu, MW Weible Neural Regeneration Research 14 (10), 1684-1694, 2019 | 29 | 2019 |
| The hallmarks of aging in Ataxia-Telangiectasia J Aguado, C Gómez-Inclán, HC Leeson, MF Lavin, Y Shiloh, ... Ageing Research Reviews 79, 101653, 2022 | 26 | 2022 |
| Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses DA Ovchinnikov, SL Withey, HC Leeson, UW Lei, A Sundarrajan, ... Human Molecular Genetics 29 (6), 990-1001, 2020 | 17 | 2020 |
| Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell types MR Shaker, A Kahtan, R Prasad, JH Lee, G Pietrogrande, HC Leeson, ... Frontiers in cell and developmental biology 10, 803061, 2022 | 12 | 2022 |
| Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution A Taherian Fard, HC Leeson, J Aguado, G Pietrogrande, D Power, ... GeroScience 46 (1), 999-1015, 2024 | 8 | 2024 |
| Reprogramming of human olfactory neurosphere-derived cells from olfactory mucosal biopsies of a control cohort HC Leeson, Z Hunter, HK Chaggar, A Mackay-Sim, EJ Wolvetang Stem Cell Research 56, 102527, 2021 | 5 | 2021 |
| Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutations HC Leeson, Z Hunter, HK Chaggar, MF Lavin, A Mackay-Sim, ... Stem Cell Research 56, 102528, 2021 | 4 | 2021 |
| Real-time live-cell flow cytometry to investigate calcium influx, pore formation, and phagocytosis by P2X7 receptors in adult neural progenitor cells HC Leeson, T Chan-Ling, MD Lovelace, JD Brownlie, MW Weible II, ... JoVE (Journal of Visualized Experiments), e59313, 2019 | 3 | 2019 |
| Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress HC Leeson, J Aguado, C Gómez-Inclán, HK Chaggar, AT Fard, Z Hunter, ... Neurobiology of Disease, 106562, 2024 | 2 | 2024 |
| Generation of iPSC lines from hereditary spastic paraplegia 56 (SPG56) patients and family members carrying CYP2U1 mutations HC Leeson, D Goh, D Coman, EJ Wolvetang Stem Cell Research 64, 102917, 2022 | 2 | 2022 |
| Deconstructing replicative senescence heterogeneity of human mesenchymal stem cells at single cell resolution reveals therapeutically targetable senescent cell sub-populations AT Fard, H Leeson, JA Perez, G Pietrogrande, D Power, CLG Inclan, ... bioRxiv, 2022.01. 24.476823, 2022 | 2 | 2022 |
| Superior Induced Pluripotent Stem Cell Generation through Phactr3-Driven Mechanomodulation of Both Early and Late Phases of Cell Reprogramming MM Chowdhury, S Zimmerman, H Leeson, CM Nefzger, JC Mar, A Laslett, ... Biomaterials Research 28, 0025, 2024 | 1 | 2024 |
| Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening ZL Hunter, HC Leeson, MR Shaker, EJ Wolvetang, L Vadlamudi Stem Cell Research 60, 102673, 2022 | 1 | 2022 |
| CD146-assisted isolation and multi-omics characterisation of human pluripotent stem cell derived cranial Schwann cell precursor-like cells. E Wolvetang, A Balachandran, K Dave, K Tiwari, C Gomez-Inclan, ... | | 2023 |
| Substrate stiffness facilitates improved induced pluripotent stem cell production through modulation of both early and late phases of cell reprogramming MM Chowdhury, S Zimmerman, H Leeson, CM Nefzger, JC Mar, A Laslett, ... bioRxiv, 2023.02. 27.530366, 2023 | | 2023 |
| Thyroid hormone and ALK5 inhibitor improve maturation of human pluripotent stem cell derived hepatocytes S Withey, D Gerrard, H Leeson, R Atkinson-Dell, S Harrison, M Baxter, ... bioRxiv, 2022.04. 28.489845, 2022 | | 2022 |
| Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patients ZL Hunter, HC Leeson, MR Shaker, EJ Wolvetang, L Vadlamudi Stem Cell Research 56, 102564, 2021 | | 2021 |
| Thyroid hormone and TGF-? inhibition drive functional maturation of human pluripotent stem cell-derived hepatocytes S Withey, D Gerrard, H Leeson, R Atkinson-Dell, S Harrison, M Baxter, ... Journal of Hepatology 73 (s1), S247-S248, 2020 | | 2020 |
