| Mixed-linkage ubiquitin chains send mixed messages MA Nakasone, N Livnat-Levanon, MH Glickman, RE Cohen, D Fushman Structure 21 (5), 727-740, 2013 | 113 | 2013 |
| Unique structural, dynamical, and functional properties of k11-linked polyubiquitin chains CA Castañeda, TR Kashyap, MA Nakasone, S Krueger, D Fushman Structure 21 (7), 1168-1181, 2013 | 78 | 2013 |
| Linkage via K27 bestows ubiquitin chains with unique properties among polyubiquitins CA Castaneda, EK Dixon, O Walker, A Chaturvedi, MA Nakasone, ... Structure 24 (3), 423-436, 2016 | 64 | 2016 |
| A general strategy for discovery of inhibitors and activators of RING and U-box E3 ligases with ubiquitin variants M Gabrielsen, L Buetow, MA Nakasone, SF Ahmed, GJ Sibbet, BO Smith, ... Molecular cell 68 (2), 456-470. e10, 2017 | 59 | 2017 |
| Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases C Chatrin, M Gabrielsen, L Buetow, MA Nakasone, SF Ahmed, ... Science Advances 6 (38), eabc0418, 2020 | 55 | 2020 |
| Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6 W Mansour, MA Nakasone, M von Delbrück, Z Yu, D Krutauz, N Reis, ... Journal of Biological Chemistry 290 (8), 4688-4704, 2015 | 54 | 2015 |
| Polyubiquitin-photoactivatable crosslinking reagents for mapping ubiquitin interactome identify Rpn1 as a proteasome ubiquitin-associating subunit M Chojnacki, W Mansour, DS Hameed, RK Singh, F El Oualid, ... Cell chemical biology 24 (4), 443-457. e6, 2017 | 40 | 2017 |
| Chemical synthesis of phosphorylated ubiquitin and diubiquitin exposes positional sensitivities of E1‐E2 enzymes and deubiquitinases S Bondalapati, W Mansour, MA Nakasone, SK Maity, MH Glickman, A Brik Chemistry–A European Journal 21 (20), 7360-7364, 2015 | 38 | 2015 |
| Extended ubiquitin species are protein-based DUB inhibitors D Krutauz, N Reis, MA Nakasone, P Siman, D Zhang, DS Kirkpatrick, ... Nature chemical biology 10 (8), 664-670, 2014 | 37 | 2014 |
| Base-CP proteasome can serve as a platform for stepwise lid formation Z Yu, N Livnat-Levanon, O Kleifeld, W Mansour, MA Nakasone, ... Bioscience reports 35 (3), e00194, 2015 | 24 | 2015 |
| Structure of UBE2K–Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension MA Nakasone, KA Majorek, M Gabrielsen, GJ Sibbet, BO Smith, ... Nature chemical biology 18 (4), 422-431, 2022 | 22 | 2022 |
| Proteomic identification and analysis of K63-linked ubiquitin conjugates J Cannon, M Nakasone, D Fushman, C Fenselau Analytical chemistry 84 (22), 10121-10128, 2012 | 21 | 2012 |
| Structural basis for the inhibitory effects of ubistatins in the ubiquitin-proteasome pathway MA Nakasone, TA Lewis, O Walker, A Thakur, W Mansour, CA Castañeda, ... Structure 25 (12), 1839-1855. e11, 2017 | 20 | 2017 |
| Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer VH Villar, MF Allega, R Deshmukh, T Ackermann, MA Nakasone, ... Nature Chemical Biology 19 (3), 292-300, 2023 | 9 | 2023 |
| An intramolecular bivalent degrader glues an intrinsic BRD4-DCAF16 interaction O Hsia bioRxiv, 2023 | 8 | 2023 |
| Characterizing polyubiquitinated forms of the neurodegenerative ubiquitin mutant UBB+1 M Chojnacki, D Zhang, M Talarowska, P Gałecki, J Szemraj, D Fushman, ... FEBS letters 590 (24), 4573-4585, 2016 | 8 | 2016 |
| Ubiquitination accomplished: E1 and E2 enzymes were not necessary MA Nakasone, DT Huang Molecular Cell 62 (6), 807-809, 2016 | 8 | 2016 |
| Targeted protein degradation via intramolecular bivalent glues O Hsia, M Hinterndorfer, AD Cowan, K Iso, T Ishida, R Sundaramoorthy, ... Nature, 1-8, 2024 | 7 | 2024 |
| Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function D Kowalczyk, MA Nakasone, BO Smith, DT Huang Life science alliance 5 (12), 2022 | 5 | 2022 |
| Mechanism of degrader-targeted protein ubiquitinability C Crowe, M Nakasone, S Chandler, MH Tatham, N Makukhin, RT Hay, ... bioRxiv, 2024.02. 05.578957, 2024 | 1 | 2024 |
David FushmanVerified email at umd.edu
