Andrew John Brown
Andrew John Brown
Professor of Biochemistry, University of New South Wales
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Cited by
Cited by
Oxysterols and atherosclerosis
AJ Brown, W Jessup
Atherosclerosis 142 (1), 1-28, 1999
ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I
IC Gelissen, M Harris, KA Rye, C Quinn, AJ Brown, M Kockx, S Cartland, ...
Arteriosclerosis, thrombosis, and vascular biology 26 (3), 534-540, 2006
Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism
AJ Brown, L Sun, JD Feramisco, MS Brown, JL Goldstein
Molecular cell 10 (2), 237-245, 2002
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast
W Fei, G Shui, B Gaeta, X Du, L Kuerschner, P Li, AJ Brown, MR Wenk, ...
Journal of Cell Biology 180 (3), 473-482, 2008
Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)
LJ Sharpe, AJ Brown
Journal of Biological Chemistry 288 (26), 18707-18715, 2013
A role for phosphatidic acid in the formation of “supersized” lipid droplets
W Fei, G Shui, Y Zhang, N Krahmer, C Ferguson, TS Kapterian, RC Lin, ...
PLoS genetics 7 (7), e1002201, 2011
Oxysterols: sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis
AJ Brown, W Jessup
Molecular aspects of medicine 30 (3), 111-122, 2009
The Akt–SREBP nexus: cell signaling meets lipid metabolism
JR Krycer, LJ Sharpe, W Luu, AJ Brown
Trends in Endocrinology & Metabolism 21 (5), 268-276, 2010
A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking
X Du, J Kumar, C Ferguson, TA Schulz, YS Ong, W Hong, WA Prinz, ...
Journal of Cell Biology 192 (1), 121-135, 2011
7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque.
AJ Brown, SL Leong, RT Dean, W Jessup
Journal of lipid research 38 (9), 1730-1745, 1997
Persistent changes in the fatty acid composition of erythrocyte membranes after moderate intake of n− 3 polyunsaturated fatty acids: study design implications
AJ Brown, E Pang, DC Roberts
The American journal of clinical nutrition 54 (4), 668-673, 1991
Sterol regulators of cholesterol homeostasis and beyond: the oxysterol hypothesis revisited and revised
S Gill, R Chow, AJ Brown
Progress in lipid research 47 (6), 391-404, 2008
Cholesterol-dependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase
S Gill, J Stevenson, I Kristiana, AJ Brown
Cell metabolism 13 (3), 260-273, 2011
Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages.
AJ Brown, RT Dean, W Jessup
Journal of lipid research 37 (2), 320-335, 1996
Dietary cosupplementation with vitamin E and coenzyme Q10 inhibits atherosclerosis in apolipoprotein E gene knockout mice
SR Thomas, SB Leichtweis, K Pettersson, KD Croft, TA Mori, AJ Brown, ...
Arteriosclerosis, thrombosis, and vascular biology 21 (4), 585-593, 2001
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis
JM Upston, X Niu, AJ Brown, R Mashima, H Wang, R Senthilmohan, ...
The American journal of pathology 160 (2), 701-710, 2002
Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis
X Du, I Kristiana, J Wong, AJ Brown
Molecular biology of the cell 17 (6), 2735-2745, 2006
Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux
J Wong, CM Quinn, AJ Brown
Arteriosclerosis, thrombosis, and vascular biology 24 (12), 2365-2371, 2004
SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR
J Wong, CM Quinn, AJ Brown
Biochemical Journal 400 (3), 485-491, 2006
Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol
IC Gelissen, AJ Brown, EL Mander, L Kritharides, RT Dean, W Jessup
Journal of Biological Chemistry 271 (30), 17852-17860, 1996
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