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Pablo Pelegrin
Pablo Pelegrin
Other namesORCID: 0000-0002-9688-1804
Biomedical Research Institute of Murcia (ror: 05m5has32), University of Murcia (ror: 03p3aeb86)
Verified email at um.es - Homepage
Title
Cited by
Cited by
Year
Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor
P Pelegrin, A Surprenant
The EMBO journal 25 (21), 5071-5082, 2006
16992006
Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor
P Pelegrin, A Surprenant
The EMBO journal 25 (21), 5071-5082, 2006
16992006
The gasdermins, a protein family executing cell death and inflammation
P Broz, P Pelegrín, F Shao
Nature Reviews Immunology 20 (3), 143-157, 2020
9562020
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
A Baroja-Mazo, F Martín-Sánchez, AI Gomez, CM Martínez, ...
Nature immunology 15 (8), 738-748, 2014
8372014
P2X7 receptor differentially couples to distinct release pathways for IL-1β in mouse macrophage
P Pelegrin, C Barroso-Gutierrez, A Surprenant
The Journal of Immunology 180 (11), 7147-7157, 2008
4792008
Cell volume regulation modulates NLRP3 inflammasome activation
V Compan, A Baroja-Mazo, G López-Castejón, AI Gomez, CM Martínez, ...
Immunity 37 (3), 487-500, 2012
4162012
Pannexin-1 couples to maitotoxin-and nigericin-induced interleukin-1β release through a dye uptake-independent pathway
P Pelegrin, A Surprenant
Journal of Biological Chemistry 282 (4), 2386-2394, 2007
3772007
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells
W Ma, H Hui, P Pelegrin, A Surprenant
Journal of Pharmacology and Experimental Therapeutics 328 (2), 409-418, 2009
3232009
MCC950 closes the active conformation of NLRP3 to an inactive state
A Tapia-Abellán, D Angosto-Bazarra, H Martínez-Banaclocha, ...
Nature chemical biology 15 (6), 560-564, 2019
3162019
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
S Gaul, A Leszczynska, F Alegre, B Kaufmann, CD Johnson, LA Adams, ...
Journal of hepatology 74 (1), 156-167, 2021
3062021
Dynamics of macrophage polarization reveal new mechanism to inhibit IL‐1β release through pyrophosphates
P Pelegrin, A Surprenant
The EMBO journal 28 (14), 2114-2127, 2009
2922009
Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense
J Garaude, R Acín-Pérez, S Martínez-Cano, M Enamorado, M Ugolini, ...
Nature immunology 17 (9), 1037-1045, 2016
2832016
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation
F Martín-Sánchez, C Diamond, M Zeitler, AI Gomez, A Baroja-Mazo, ...
Cell Death & Differentiation 23 (7), 1219-1231, 2016
2632016
AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3
A Denes, G Coutts, N Lénárt, SM Cruickshank, P Pelegrin, J Skinner, ...
Proceedings of the National Academy of Sciences 112 (13), 4050-4055, 2015
2562015
The participation of plasma membrane hemichannels to purinergic signaling
A Baroja-Mazo, M Barberŕ-Cremades, P Pelegrín
Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (1), 79-93, 2013
2392013
NLRP3 and pyroptosis blockers for treating inflammatory diseases
RC Coll, K Schroder, P Pelegrín
Trends in pharmacological sciences 43 (8), 653-668, 2022
2202022
P2X7 receptor activation enhances SK3 channels-and cystein cathepsin-dependent cancer cells invasiveness
B Jelassi, A Chantome, F Alcaraz-Perez, A Baroja-Mazo, ML Cayuela, ...
Oncogene 30 (18), 2108-2122, 2011
2202011
The NLRP3 and pyrin inflammasomes: implications in the pathophysiology of autoinflammatory diseases
C de Torre-Minguela, P Mesa del Castillo, P Pelegrín
Frontiers in immunology 8, 246244, 2017
2152017
The P2X7 receptor–pannexin connection to dye uptake and IL-1β release
P Pelegrin, A Surprenant
Purinergic signalling 5, 129-137, 2009
1992009
Inflammasomes in liver fibrosis
F Alegre, P Pelegrin, AE Feldstein
Seminars in liver disease 37 (02), 119-127, 2017
1882017
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