Michael Robert Beard
Michael Robert Beard
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Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein
M Okuda, K Li, MR Beard, LA Showalter, F Scholle, SM Lemon, ...
Gastroenterology 122 (2), 366-375, 2002
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus
H Lerat, M Honda, MR Beard, K Loesch, J Sun, Y Yang, M Okuda, ...
Gastroenterology 122 (2), 352-365, 2002
A phylogenetically conserved stem-loop structure at the 5′ border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation
M Honda, MR Beard, LH Ping, SM Lemon
Journal of virology 73 (2), 1165-1174, 1999
Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees
CB Bigger, B Guerra, KM Brasky, G Hubbard, MR Beard, BA Luxon, ...
Journal of virology 78 (24), 13779-13792, 2004
Large deletions induced by Cas9 cleavage
F Adikusuma, S Piltz, MA Corbett, M Turvey, SR McColl, KJ Helbig, ...
Nature 560 (7717), E8-E9, 2018
Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector
KJ Helbig, DTY Lau, L Semendric, HAJ Harley, MR Beard
Hepatology 42 (3), 702-710, 2005
HIV-1 infection of human macrophages directly induces viperin which inhibits viral production
N Nasr, S Maddocks, SG Turville, AN Harman, N Woolger, KJ Helbig, ...
Blood, The Journal of the American Society of Hematology 120 (4), 778-788, 2012
The role of viperin in the innate antiviral response
KJ Helbig, MR Beard
Journal of molecular biology 426 (6), 1210-1219, 2014
The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A
KJ Helbig, NS Eyre, E Yip, S Narayana, K Li, G Fiches, EM McCartney, ...
Hepatology 54 (5), 1506-1517, 2011
Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin
KJ Helbig, JM Carr, JK Calvert, S Wati, JN Clarke, NS Eyre, SK Narayana, ...
PLoS neglected tropical diseases 7 (4), e2178, 2013
Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection
FJ Ryan, CM Hope, MG Masavuli, MA Lynn, ZA Mekonnen, AEL Yeow, ...
BMC medicine 20, 1-23, 2022
Interferon-stimulated genes as enhancers of antiviral innate immune signaling
KM Crosse, EA Monson, MR Beard, KJ Helbig
Journal of innate immunity 10 (2), 85-93, 2018
The interferon-induced transmembrane proteins, IFITM1, IFITM2, and IFITM3 inhibit hepatitis C virus entry
SK Narayana, KJ Helbig, EM McCartney, NS Eyre, RA Bull, A Eltahla, ...
Journal of Biological Chemistry 290 (43), 25946-25959, 2015
Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells
K Otani, M Korenaga, MR Beard, K Li, T Qian, LA Showalter, AK Singh, ...
Gastroenterology 128 (1), 96-107, 2005
An infectious molecular clone of a Japanese genotype 1b hepatitis C virus
MR Beard, G Abell, M Honda, A Carroll, M Gartland, B Clarke, K Suzuki, ...
Hepatology 30 (1), 316-324, 1999
Expression of the CXCR3 ligand I‐TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation
KJ Helbig, A Ruszkiewicz, L Semendric, HAJ Harley, SR McColl, ...
Hepatology 39 (5), 1220-1229, 2004
CD4+ T-Cell Deficiency in HIV Patients Responding to Antiretroviral Therapy Is Associated With Increased Expression of Interferon-Stimulated Genes in CD4+ T …
S Fernandez, S Tanaskovic, K Helbig, R Rajasuriar, M Kramski, ...
The Journal of infectious diseases 204 (12), 1927-1935, 2011
Cellular response to conditional expression of hepatitis C virus core protein in Huh7 cultured human hepatoma cells
K Li, T Prow, SM Lemon, MR Beard
Hepatology 35 (5), 1237-1246, 2002
Viperin is an important host restriction factor in control of Zika virus infection
KH Van der Hoek, NS Eyre, B Shue, O Khantisitthiporn, K Glab-Ampi, ...
Scientific reports 7 (1), 4475, 2017
Dengue virus infection induces upregulation of GRP78, which acts to chaperone viral antigen production
S Wati, ML Soo, P Zilm, P Li, AW Paton, CJ Burrell, M Beard, JM Carr
Journal of virology 83 (24), 12871-12880, 2009
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