Determining the mechanisms of lapatinib-induced diarrhoea using a rat model JM Bowen, BJ Mayo, E Plews, E Bateman, A Wignall, AM Stringer, ... Cancer chemotherapy and pharmacology 74, 617-627, 2014 | 32 | 2014 |
Enhancing the cellular uptake and antibacterial activity of rifampicin through encapsulation in mesoporous silica nanoparticles P Joyce, H Ulmefors, S Maghrebi, S Subramaniam, A Wignall, ... Nanomaterials 10 (4), 815, 2020 | 24 | 2020 |
Targeting neratinib-induced diarrhea with budesonide and colesevelam in a rat model KR Secombe, IA Ball, J Shirren, AD Wignall, J Finnie, D Keefe, ... Cancer chemotherapy and pharmacology 83, 531-543, 2019 | 20 | 2019 |
Enhancement of abiraterone acetate oral bioavailability by supersaturated-silica lipid hybrids HB Schultz, AD Wignall, N Thomas, CA Prestidge International journal of pharmaceutics 582, 119264, 2020 | 19 | 2020 |
Development and in vitro evaluation of 5-fluorouracil-eluting stents for the treatment of colorectal cancer and cancer-related obstruction M Arafat, P Fouladian, A Wignall, Y Song, A Parikh, H Albrecht, ... Pharmaceutics 13 (1), 17, 2020 | 18 | 2020 |
The GLP-2 analogue elsiglutide reduces diarrhoea caused by the tyrosine kinase inhibitor lapatinib in rats BJ Mayo, KR Secombe, AD Wignall, E Bateman, D Thorpe, C Pietra, ... Cancer chemotherapy and pharmacology 85, 793-803, 2020 | 16 | 2020 |
Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report JK Coller, JM Bowen, IA Ball, HR Wardill, YZA van Sebille, ... Cancer chemotherapy and pharmacology 79, 431-434, 2017 | 14 | 2017 |
Investigation of effect of nutritional drink on chemotherapy-induced mucosal injury and tumor growth in an established animal model E Bateman, J Bowen, A Stringer, B Mayo, E Plews, A Wignall, ... Nutrients 5 (10), 3948-3963, 2013 | 14 | 2013 |
Serum-derived bovine immunoglobulin/protein isolate in the alleviation of chemotherapy-induced mucositis E Bateman, E Weaver, G Klein, A Wignall, B Wozniak, E Plews, B Mayo, ... Supportive Care in Cancer 24, 377-385, 2016 | 13 | 2016 |
Protein adsorption determines pulmonary cell uptake of lipid-based nanoparticles S Subramaniam, P Joyce, L Donnellan, C Young, A Wignall, P Hoffmann, ... Journal of Colloid and Interface Science 641, 36-47, 2023 | 11 | 2023 |
An ex vivo investigation of the intestinal uptake and translocation of nanoparticles targeted to Peyer’s patches microfold cells Z Jia, A Wignall, C Prestidge, B Thierry International Journal of Pharmaceutics 594, 120167, 2021 | 10 | 2021 |
Liquid Crystal Nanoparticles Enhance Tobramycin Efficacy in a Murine Model of Pseudomonas aeruginosa Biofilm Wound Infection CR Thorn, A Wignall, Z Kopecki, A Kral, CA Prestidge, N Thomas ACS Infectious Diseases 8 (4), 841-854, 2022 | 9 | 2022 |
Antibiotic treatment targeting gram negative bacteria prevents neratinib-induced diarrhea in rats KR Secombe, IA Ball, AD Wignall, E Bateman, DM Keefe, JM Bowen Neoplasia 30, 100806, 2022 | 8 | 2022 |
Contrasting anti-obesity effects of smectite clays and mesoporous silica in Sprague-Dawley rats P Joyce, TJ Dening, TR Meola, A Wignall, H Ulmefors, M Kovalainen, ... ACS Applied Bio Materials 3 (11), 7779-7788, 2020 | 8 | 2020 |
Selective MMP inhibition, using AZD3342, to reduce gastrointestinal toxicity and enhance chemoefficacy in a rat model RJ Gibson, YZA Van Sebille, HR Wardill, A Wignall, J Shirren, IA Ball, ... Chemotherapy 63 (5), 284-292, 2019 | 8 | 2019 |
Vascular endothelial growth factor (VEGF), transforming growth factor beta (TGFβ), angiostatin, and endostatin are increased in radiotherapy-induced gastrointestinal toxicity RL Stansborough, EH Bateman, N Al-Dasooqi, JM Bowen, A Wignall, ... International Journal of Radiation Biology 94 (7), 645-655, 2018 | 8 | 2018 |
Liquid crystal nanoparticle platform for increased efficacy of cationic antimicrobials against biofilm infections CR Thorn, Z Kopecki, A Wignall, A Kral, CA Prestidge, N Thomas Nanomedicine: Nanotechnology, Biology and Medicine 42, 102536, 2022 | 7 | 2022 |
Harnessing the potential of nanostructured formulations to mimic the food effect of lurasidone TR Meola, P Joyce, A Wignall, KE Bremmell, CA Prestidge International Journal of Pharmaceutics 608, 121098, 2021 | 7 | 2021 |
Effects of a novel toll-like receptor 4 antagonist IAXO-102 in a murine model of chemotherapy-induced gastrointestinal toxicity JSY Tam, EE Crame, AS Elz, JK Coller, A Wignall, CA Prestidge, ... Cancer Chemotherapy and Pharmacology 90 (3), 267-278, 2022 | 6 | 2022 |
Pathophysiology of neratinib-induced diarrhea in male and female rats: microbial alterations a potential determinant KR Secombe, IA Ball, J Shirren, AD Wignall, DM Keefe, JM Bowen Breast Cancer 28, 99-109, 2021 | 6 | 2021 |