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Dr. Pakhuri Mehta
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Enigmatic Histamine Receptor H4 for Potential Treatment of Multiple Inflammatory, Autoimmune, and Related Diseases
P Mehta, P Miszta, P Rzodkiewicz, O Michalak, P Krzeczyński, S Filipek
Life 10 (4), 50, 2020
262020
Structure-based screening, ADMET profiling, and molecular dynamic studies on mGlu2 receptor for identification of newer antiepileptic agents
R Malik, P Mehta, S Srivastava, BS Choudhary, M Sharma
Journal of Biomolecular Structure and Dynamics 35 (16), 3433-3448, 2017
172017
Identification of chemically diverse GABAA agonists as potential anti-epileptic agents using structure-guided virtual screening, ADMET, quantum mechanics and clinical …
P Mehta, S Srivastava, M Sharma, I Singh, R Malik
International journal of biological macromolecules 119, 1113-1128, 2018
142018
Identification of novel acetylcholinesterase inhibitors through e-pharmacophore-based virtual screening and molecular dynamics simulations
R Malik, BS Choudhary, S Srivastava, P Mehta, M Sharma
Journal of Biomolecular Structure and Dynamics 35 (15), 3268-3284, 2017
132017
Development and validation of related substances method by HPLC for analysis of naproxen in naproxen tablet formulations
P Mehta, CS Sharma, D Nikam, MS Ranawat
International Journal of pharmaceutical sciences and drug research 4 (1), 63-69, 2012
132012
Molecular modeling of histamine receptors—Recent advances in drug discovery
P Mehta, P Miszta, S Filipek
Molecules 26 (6), 1778, 2021
122021
Pharmacophore modeling, 3D-QSAR, and in silico ADME prediction of N-pyridyl and pyrimidine benzamides as potent antiepileptic agents
R Malik, P Mehta, S Srivastava, BS Choudhary, M Sharma
Journal of Receptors and Signal Transduction 37 (3), 259-266, 2017
122017
High throughput virtual screening and in silico ADMET analysis for rapid and efficient identification of potential PAP248-286 aggregation inhibitors as anti-HIV agents
R Malik, D Bunkar, BS Choudhary, S Srivastava, P Mehta, M Sharma
Journal of Molecular Structure 1122, 239-246, 2016
112016
N-(4-Hydroxyphenyl)-3,4,5-trimethoxybenzamide derivatives as potential memory enhancers: synthesis, biological evaluation and molecular simulation studies
P Piplani, M Sharma, P Mehta, R Malik
Journal of Biomolecular Structure and Dynamics 36 (7), 1867-1877, 2018
102018
Development and validation of stability indicating uv spectrophotometric method for estimation of naproxen in pharmaceutical dosage form
P Mehta, CS Sharma, D Nikam, MS Ranawat
Asian J Biochem Pharm Res 2012; 1: 291 303, 2012
72012
Simultaneous Method Development and Validation of Anastrozole Along with Piperine: Degradation Studies and Degradants Characterization Using LC-QTOF-ESI-MS Along with In-silico …
KJ Susanna, R Gajbhiye, B Sarmah, SD Pawar, P Mehta, US Murty, ...
Current Drug Metabolism 23 (2), 113-130, 2022
62022
Computationally guided identification of Akt-3, a serine/threonine kinase inhibitors: Insights from homology modelling, structure-based screening, molecular dynamics and …
S Srivastava, P Mehta, O Sharma, M Sharma, R Malik
Journal of Biomolecular Structure and Dynamics 38 (14), 4179-4188, 2020
52020
Antioxidant activity of novel diosgenin derivatives: Synthesis, biological evaluation, and in silico ADME prediction
O Michalak, P Krzeczyński, A Jaromin, P Cmoch, M Cybulski, K Trzcińska, ...
Steroids 188, 109115, 2022
42022
Discovery and identification of putative adenosine kinase inhibitors as potential anti-epileptic agents from structural insights
P Mehta, R Malik
Journal of Biomolecular Structure and Dynamics 38 (18), 5320-5337, 2020
42020
Discovery of novel chemotypes for competitive AMPA receptor antagonists as potential antiepileptic agents through structure-based virtual screening of natural products library
P Mehta, S Srivastava, M Sharma, R Malik
Structural Chemistry 30, 1159-1172, 2019
42019
Molecular dynamics insights for PI3K-δ inhibition & structure guided identification of novel PI3K-δ inhibitors
S Srivastava, B Singh Choudhary, P Mehta, Sukanya, M Sharma, R Malik
Journal of Biomolecular Structure and Dynamics 37 (9), 2404-2414, 2019
42019
UHPLC-DAD Method Development and Validation: Degradation Kinetic, Stress Studies of Farnesol and Characterization of Degradation Products Using LC-QTOF-ESI-MS with in silico …
SK Moinuddin, RL Gajbhiye, P Mehta, B Sarmah, US Murty, ...
Journal of Chromatographic Science 60 (9), 817-831, 2022
32022
Discovery of thiazolidin-4-one analogue as selective GSK-3β inhibitor through structure based virtual screening
BS Choudhary, P Mehta, S Bach, S Ruchaud, T Robert, B Josselin, ...
Bioorganic & Medicinal Chemistry Letters 52, 128375, 2021
32021
Probing voltage sensing domain of KCNQ2 channel as a potential target to combat epilepsy: a comparative study
P Mehta, S Srivastava, BS Choudhary, M Sharma, R Malik
Journal of Receptors and Signal Transduction 37 (6), 578-589, 2017
32017
Identification of CNS compatible small molecules as glycogen synthase kinase-3β (GSK-3β) inhibitors through structure-based virtual screening
S Sukanya, BS Choudhary, P Mehta, S Filipek, R Malik
Medicinal Chemistry Research 31 (9), 1545-1557, 2022
12022
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