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Paul O'Callaghan
Paul O'Callaghan
Dept. Medical Cell Biology, Uppsala University, Sweden
Verified email at mcb.uu.se - Homepage
Title
Cited by
Cited by
Year
Animal models of amyloid‐β‐related pathologies in Alzheimer’s disease
O Philipson, A Lord, A Gumucio, P O’Callaghan, L Lannfelt, LNG Nilsson
The FEBS journal 277 (6), 1389-1409, 2010
1362010
Heparan sulfate mediates amyloid-beta internalization and cytotoxicity
E Sandwall, P O'Callaghan, X Zhang, U Lindahl, L Lannfelt, JP Li
Glycobiology 20 (5), 533-541, 2010
1172010
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates
J Rostami, T Mothes, M Kolahdouzan, O Eriksson, M Moslem, J Bergström, ...
Journal of neuroinflammation 18 (1), 124, 2021
1062021
Heparan sulfate accumulation with Aβ deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells
P O'Callaghan, E Sandwall, JP Li, H Yu, R Ravid, ZZ Guan, ...
Brain pathology 18 (4), 548-561, 2008
962008
Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein
F Noborn, P O'Callaghan, E Hermansson, X Zhang, JB Ancsin, ...
Proceedings of the National Academy of Sciences 108 (14), 5584-5589, 2011
892011
Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain
X Zhang, B Wang, P O’Callaghan, E Hjertström, J Jia, F Gong, E Zcharia, ...
Acta neuropathologica 124, 465-478, 2012
762012
Microglial heparan sulfate proteoglycans facilitate the cluster-of-differentiation 14 (CD14)/Toll-like receptor 4 (TLR4)-dependent inflammatory response
P O'Callaghan, JP Li, L Lannfelt, U Lindahl, X Zhang
Journal of Biological Chemistry 290 (24), 14904-14914, 2015
562015
SPECT imaging of distribution and retention of a brain-penetrating bispecific amyloid-β antibody in a mouse model of Alzheimer’s disease
T Gustavsson, S Syvänen, P O’Callaghan, D Sehlin
Translational Neurodegeneration 9 (1), 37, 2020
432020
Heparan sulfate proteoglycans as relays of neuroinflammation
P O’Callaghan, X Zhang, JP Li
Journal of Histochemistry & Cytochemistry 66 (4), 305-319, 2018
352018
MicroRNA-24 suppression of N-deacetylase/N-sulfotransferase-1 (NDST1) reduces endothelial cell responsiveness to vascular endothelial growth factor A (VEGFA)
Z Kasza, PF Fuchs, C Tamm, AS Eriksson, P O'Callaghan, F Heindryckx, ...
Journal of Biological Chemistry 288 (36), 25956-25963, 2013
342013
Modular microfluidic systems cast from 3D-printed molds for imaging leukocyte adherence to differentially treated endothelial cultures
R Hernández Vera, P O’Callaghan, N Fatsis-Kavalopoulos, J Kreuger
Scientific reports 9 (1), 11321, 2019
212019
Vascular sprouts induce local attraction of proangiogenic neutrophils
G Christoffersson, J Lomei, P O'Callaghan, J Kreuger, S Engblom, ...
Journal of leukocyte biology 102 (3), 741-751, 2017
212017
FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation
J Heldin, P O'Callaghan, R Hernández Vera, PF Fuchs, P Gerwins, ...
Cellular Signalling 40 (December 2017), 125-132, 2017
202017
The β-cell primary cilium is an autonomous Ca2+ compartment for paracrine GABA signaling
GM Sanchez, TC Incedal, J Prada, P O’Callaghan, O Dyachok, ...
Journal of Cell Biology 222 (1), e202108101, 2022
162022
Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways
P O’Callaghan, F Noborn, D Sehlin, J Li, L Lannfelt, U Lindahl, X Zhang
Amyloid 21 (2), 76-87, 2014
152014
Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution
N Fatsis-Kavalopoulos, P O'Callaghan, B Xie, RH Vera, O Idevall-Hagren, ...
Lab on a Chip 19 (6), 1071-1081, 2019
132019
Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells
P O'Callaghan, A Engberg, O Eriksson, N Fatsis-Kavalopoulos, C Stelzl, ...
Journal of Cell Science 135 (7), jcs258809, 2022
122022
An open source extrusion bioprinter based on the E3D motion system and tool changer to enable FRESH and multimaterial bioprinting
A Engberg, C Stelzl, O Eriksson, P O’Callaghan, J Kreuger
Scientific Reports 11 (1), 21547, 2021
112021
Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: Relevance to Alzheimer’s disease
X Zhang, P O’Callaghan, H Li, Y Tan, G Zhang, U Barash, X Wang, ...
Acta neuropathologica communications 9 (1), 84, 2021
82021
Conference: Heparan sulphate/heparin binds transthyretin and promotes its fibrillogenesis
F Noborn, P O'Callaghan, I Dacklin, JB Ancsin, A Damas, E Lundgren, ...
Amyloid-Journal of Protein Folding Disorders 17, 40-40, 2010
32010
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